Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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Category: Weight Loss

So You Want to Take Alli?

The oily spotting continues. Healthbolt has the money quote on new diet drug Alli:

“You can also bet your bottom dollar that GSK will be running ads of fabulous looking people living skinny-happy lives on alli in a field of wheat somewhere. They sure as hell won?t be running ads about 16 year old girls, malnourished as-is because of eating disorders (and this is who?s buying over the counter diet pills) passing out in gym class because they have no vitamins in their body…”

There will also no doubt be a floppy-eared puppy somewhere in that field of wheat – though I’m betting on a field of buttercups and violets myself.

For further consideration: at best, this new wonder drug will yield you a 5-10 pound weight loss…after 6 months! And that’s if you diet. And if you exercise. And that number may not be right, anyway, because the study was so shoddy.

I could lose 5 pounds on a bet in a week and it would still be healthier and safer than the Alli method.

If you work out for just 30 minutes a day and simultaneously cut just 200 calories from your daily intake (we’re talking a soda or a latte or just one standard serving of carbs, Apples), you’ll lose 5-10 pounds in one month. Yes. ONE MONTH. And that’s without a drug.

It should never take six months to lose 5 pounds. It should take about two weeks, and you certainly don’t need a drug to do that.

Among things that will take off 5 pounds in far less time than Alli:

(bear in mind this study isn’t totally proven, but then neither is Alli’s)

Yawning

Stretching in your chair

Rolling over one extra time in bed

Smiling at the mailman for once

Thinking about losing weight

Wondering if your friends are thinking about losing weight

Not thinking about losing weight

Remembering you need to put the clothes in the dryer

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[tags]Healthbolt, GSK, Alli, eating disorders, diet drug[/tags]

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And This Is What I Call a Deal-Breaker

I’m sure you’ve heard the headlines about Orlistat, the obesity drug, being approved for OTC use. What you may not have heard about are the side effects of this fat-blocking drug. Orlistat, which will still be distributed by Rx as Xenical for morbidly obese patients, will now be sold as Alli in drugstores nationwide. A magic pill it ain’t, Apples. I have a big (pardon the pun) problem with this drug, for several reasons. 1. How It Works I have no doubt that Alli is going to fly off the shelves faster than bananas in a monkey farm. People want to lose weight without making changes, and that’s the unfortunate truth. Some of us are lazy; some are depressed; some don’t have the information; and like children believing in Santa, many simply want to believe in a magic cure. These folks are the ones GlaxoSmithKline is banking on. Drug companies love a sucker. Alli “works” (and even this is highly debatable) by blocking fat absorption. This is problematic, to put it lightly. First of all, fat does not make you fat. The human body was meant to operate in a fat-burning metabolic state. Whether you believe in God or cite Darwin or both, there’s absolutely no disputing this fact. The advent of grain agriculture is a new thing for humans, relatively speaking, and the transition from a flesh-and-vegetable diet to a grain-and-sugar diet has humans suffering in a glucose-burning state. The side effects of this high-sugar diet are horrendous: inflammation, heart disease, depression, insomnia, diabetes, mental degeneration, aging, obesity and cancer. Do you still really want to block fat? People I coach are shocked when I put them on a higher-fat diet because mainstream wisdom still worships at the altar of low-fat. Know what happens? Infections clear, cholesterol drops, energy increases, anxiety dissipates, skin glows, and the pounds melt away. Second, reducing fat deprives your body of vital nutrients, vitamins and antioxidants, which all need fat to metabolize. Blocking fat means you can’t properly absorb critical nutrients, which is why Alli has to be taken with a multivitamin to offset some of the damage. 2. The Law of Unintended Consequences: Oily Stools? Alli is available under conditional approval. This is the same FDA approval stamp that got us into the HRT and Cox-2 disasters. How many thousands of women suffered from breast cancer and how many people had heart attacks as a result of these reckless approvals? Conditional approval. As I mentioned the other day in an update on the FDA’s drug woes, conditional approval is a process by which the FDA essentially allows the burden of safety to rest with drug companies. (Yes: more often than you want to know, the FDA lets pharmaceutical companies begin marketing and selling a drug before lengthy testing has been conducted.) This tacit trust is just super-duper for drug companies eager to sop up years of product development costs with fast cash, but I’m stumped as to how this is beneficial for actual … Continue reading “And This Is What I Call a Deal-Breaker”

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Hoodia: So Much More Than Latin for ‘Hoodie’

The claims about hoodia are about as accurate as that headline.

Don’t get hoodiawinked. Here’s the truth about this alleged weight-loss miracle cactus (Latin for…well, cactus).

Does Hoodia Work?

In a word, no. There’s no proof that hoodia works to help you lose weight – not even a little. Myths, legends, stories and anecdotes are convincing because they resonate with emotional desires (which is why any profitable scam manages to make money). Hoodia is no exception – this new fat-reduction fad product has no scientific evidence to support the claims. Do a little digging around, and you’ll learn that the hoodia being sold is not even the real thing anyway.

Hoodia is a cactus from South Africa. There are 20 types, but gordonii is the only one that actually quells hunger. Here’s the catch: this version of hoodia is endangered and therefore protected by law. It’s not allowed to be harvested and can only be exported to botanists for study.

Now, the chow-suppressing molecule in gordonii hoodia is called P57. Right now, a company called Phytofarm owns it, and you won’t be getting your hands on it anytime soon. Unilever and Pfizer both paid big sums to Phytopharm to toy with hoodia over the last three years, to no avail. Why? Because it doesn’t work for weight loss.

Hoodia products on the market are not real hoodia (and there have been a flurry of government cease-and-desist orders in attempts to stop this scam). Even real hoodia doesn’t work when it’s powdered, processed or the P57 molecule is extracted. You have to eat actual pieces of the plant. Moreover, hoodia does not burn fat – its function is to slow the metabolism, which often has the reverse desired effect. Your body thinks it’s starving, so it hangs on to fat stores even more aggressively.

Web it out:

Clickativity

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[tags]Hoodia, cactus, gordonii, fat reduction, Phytofarm[/tags]

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The Tuesday 10

The Top 10 Tips for: Getting Fit Wanna get fit? If you’re just starting out, keep in mind it’s not going to happen overnight…but you can be lookin’ pretty good by next month with these tips. The reason most get-ripped regimens fail is because we simply expect way too much, way too soon. Big changes in your body require big changes in your lifestyle. Period. It took your whole life to be the way you are now, right? It’s going to take more than two days to start making changes to that. But these 10 pointers will get you started – and you’ll notice some very pleasant effects if you stick with them. You’ll be surprised that very few of them have anything to do with lifting so much as a finger. Fitness is many factors coming together – it’s a lot more than just hitting the gym (thank goodness). 1. Cut calories the lazy way. To shape up, you must reduce your fat so your muscles can start doing their thing. This is actually very, very easy to do: every time you go to put something in your mouth, don’t. No, no, just kidding! You have to eat. Here’s what to do: – in restaurants, eat half the plate and get the rest to go. Don’t eat it when you get home – let the dog or the neighbor kid with hollow legs enjoy it. – immediately run out and get yourself some 7″ plates. Those are now your dinner plates. Preso, portion sizes reduced. – Don’t eat anything crunchy, creamy, pale or fried. This pretty much takes care of all high-calorie, unhealthy foods. Examples: chips, ranch dressing, bread sticks, chicken nuggets. We know, veggies are crunchy. It’s not an absolute rule. Just a guide. – Switch all snacks to cherry tomatoes, carrot sticks or broccoli florets. Depending on how much you snack, you’ll save 200 to 600 calories a day doing this. 2. Don’t drink your calories. A little coffee or tea is one thing. But soda, shakes, iced coffee drinks, juices and energy drinks are overflowing with calories, which you don’t want, right? Don’t waste precious caloric intake on liquids that don’t fill you up. 3. Absolutely no drive-through or delivery food. McDonald’s likes to run those “Mommy and me” ads that show slender young Mommy eating salad while her ringlet-bedecked tutu-wearing darling is busy dipping apples into some sweet sap. Please. This stuff is generally more marketing than meaningful, so read the ingredients and avoid anything sweet or fried. Best to stick to fresher fare. 4. Move it! You don’t have to become a gym rat. You don’t have to sign up for the local 10K. But you need to move. Simply put, any movement that is more than you currently do is going to be effective. If you don’t ever work out, walking around the neighborhood for 20 minutes a day, 5 days a week is going to start having an impact after just two … Continue reading “The Tuesday 10”

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I Can’t Eat Anything!

Junior Apple Mike F. writes: “Mark, what can I eat? I hear dairy is bad, fat is bad, then fat is good, but some fat is bad, carbs are bad, but fiber is good. There is nothing left. I can’t even have milk in my tea now – not that I would be caught sipping tea. But if I wanted to is the point. What’s a guy supposed to eat?” Good question, Mike. The answer: just about everything. I am pretty disciplined (according to my kids, I’m a drill sergeant). I don’t really “do” carbs, I definitely avoid any junk or processed food, and I try to eat organic. But even being so careful about what goes on my plate, I’d say honestly I get a lot more flavor and variety than some people I know who insist on a steady diet of burgers, beers and pizzas. The truth is, “fun” foods like nachos, pizza and tacos all taste the same: the texture is usually a mix of creamy or crunchy, there’s a lot of salt, some meat-type seasoning, and sugar. Eat that stuff and you’re starving the next hour. You can eat salad and be a man about it. Seriously. I’m fitter, have more muscle mass and I’m in better shape than I’ve ever been at 5’10”, 165 lbs. and 8% body fat. I do it with a heavy supply of vegetables, of all things. I never worry too much about fat because I eat a lot of “good” fats, which really aren’t too hard to identify. More on that in a moment. But honestly, I never am deprived, hungry or suffer from any cravings. Actually, I refuse to eat something that isn’t delicious, period. To me, the relentlessly boring, salty, familiar flavor of most processed foods is not delicious. The fact that they’re also totally unhealthy is almost a side issue. This morning, for example, I had my cup of joe with a little organic H&H. I don’t always eat breakfast (there I go breaking all the holy grails of health). This morning I had some scrambled Omega-enhanced eggs, and sometimes I’ll have a piece of fruit or a protein smoothie. I confess I don’t eat a lot of fruit (my wife jokes that men like the idea of fruit but don’t always know what to do with it). I like to get my fiber from vegetables since they’re lower in sugar and have more nutrients than fruit. For a snack I’ll grab a piece of fruit, cherry tomatoes or some almonds. I completely avoid processed snacks like chips and candy. Fresh stuff just tastes better – but it will take your body some time to readjust its tastes if you’ve been a junk food kind of guy. For lunch (speaking of lunch…): I always eat a huge salad. I’ve done so for 20 years. But no regular salad – I add in seafood or turkey, mountains of colorful chopped up veggies, and drizzle some balsamic vinegar on … Continue reading “I Can’t Eat Anything!”

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Lose Weight, Lose Cancer?

A new study seems to confirm that losing even a few pounds can help reduce a man’s prostate cancer risk. But what’s most intriguing about the latest and greatest findings is the following:

The studies reinforce the notion that prostate cancer is not a single cancer but a family of diseases, each fueled by different chemicals…

Cancer, once thought to be a “single” disease, may in fact be more similar to a condition caused by an association of factors or culprits: stress, oxidation, cell mutation, even fungus. We certainly know now that even within types of cancers, the pathologies are incredibly complicated.

It’s an ongoing issue we’ll be getting into more deeply in the future. For now, give the article a click, and spread the word: weight loss is almost always a benefit to health.

What are your thoughts, Apples?

[tags] oncology, cancer risk, cell mutation, cancer etiology [/tags]

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