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Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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August 26 2018

Weekend Link Love — Edition 518

By Mark Sisson
14 Comments

Research of the Week

Olympic gold medalists die earlier than silver medalists (on average).

Despite increased HPV vaccine uptake, HPV-related cancers are on the rise.

Cardio and weight lifting have different effects on our hormones (so do both).

If you’re sensitive to alcohol, you might be sensitive to sleep deprivation, too.

Sun exposure alters gut bacteria independent of vitamin D.

New Primal Blueprint Podcasts

Episode 273: Seamus Mullen: Host Elle Russ chats with Seamus Mullen, an award-winning New York chef and cookbook author who used diet to cure his rheumatoid arthritis.

Each week, select Mark’s Daily Apple blog posts are prepared as Primal Blueprint Podcasts. Need to catch up on reading, but don’t have the time? Prefer to listen to articles while on the go? Check out the new blog post podcasts below, and subscribe to the Primal Blueprint Podcast here so you never miss an episode.

Interesting Blog Posts

Parenting an infant can be scary, but at least you know not to give your teething kid opium.

An interesting hypothesis for why those paleolithic Venus statues were so curvaceous.

Don’t count out Monsanto just yet.

Media, Schmedia

Veganism isn’t the answer.

Is a diverse diet actually important (or helpful)?

Everything Else

A Denisovan and a Neanderthal, sittin’ in a cave

Kanye gets it.

It works in monkeys. Now, researchers are going to try reprogrammed stem cells in human Parkinson’s patients.

Army of ticks…”

Teens prefer texting to books.

Things I’m Up to and Interested In

Study I’m reading: Health coaching works.

Analysis I enjoyed: Regarding the effects drinking (and not drinking) has on mortality.

Concept I’m pondering: Does purported longevity drug rapamycin slow down time?

Announcement I’m pleased to, well, announce: PETA has liberated the animals!

Interesting line in a study’s conclusion: “Hyperlipidemia is not an important cause of coronary atherosclerosis.”

Recipe Corner

Time Capsule

One year ago (Aug 19 – Aug 25)

Comment of the Week

“I know the ‘and his dog’ was meant as a joke, but our dog has bone cancer in her humerus. Rather than the recommended amputation, chemo and radiation treatment path, we have her on several holistic treatments and changed her diet to Keto. No glycogen to feed her cancer cells, and cancer cells (which need lots of energy) don’t do well on ketones. We are just months in, but she is enjoying life everyday.”

– That’s dogs for ya, Jan. Good luck!

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14 thoughts on “Weekend Link Love — Edition 518”

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  1. From the UV and mouse microbiome study, the authors write the following in the General Discussion:

    “Among Firmicutes, the genus Coprococcus was enriched with UVR exposure. This bacterium produces butyric acid, a short-chain fatty acid with known anti-inflammatory effects which is depleted in paediatric patients with active inflammatory bowel disease [31]. Interestingly, we recently reported the depletion of the genus Coprococcus with high vitamin D diets, which was also associated with more severe DSS colitis [7], again suggesting different effects of UVR versus dietary vitamin D on specific bacterial taxa.”

    It is interesting to consider the potential translational significance of this effect in humans. Could optimal sun exposure enhance the therapeutic effects of a ketogenic diet by increasing the colonic microbes that produce ketone body metabolites? And the contrast in the effect of dietary vitamin D and UV light exposure is intriguing.

  2. Re the Venuses: there’s something I’ve never been able to get past. If these Venuses were made by women looking down at their own bodies, how did they manage the intricate detailing in the crown of the head – as with Willendorf – and the view of the back?

    Further, women can usually manage to see their feet! Even if their bellies are so huge that they can’t see past them when standing, they know jolly well that they have feet. They know as well that they have hands, and bellies and boobs don’t block the view of the hands. If they can’t see their backs or the tops of their heads, but nevertheless sculpt them, why would they ignore their appendages?

    1. The back had the least accurate shape and proportions, the head was by fair the plainest (as generic as it gets), and the appendages wouldn’t interest someone who is studying the effects of pregnancy on her own physical constitution because they practically don’t change. The areas of the body best represented are the central ones; that fact matches the hypothesis (pregnant women exploring their bodies).

      It can also match the hypothesis that these statues are a sexual extended phenotype pursued by men of those eras, but that particular conjecture doesn’t cover how those men got the subjective proportions of a woman body right. Unless they beheaded women shorter than themselves and looked below from over the neck stump.

  3. “Hyperlipidemia is not an important cause of coronary atherosclerosis.”

    But what about the $30 billion/year spent on statins?

  4. On the Animal Crackers, the PETA move was pointlessly late. Possibly a merchandising change was already in work. Barnum’s folded its last tent last year. Much of the population was already at the point of not knowing what the package art was supposed to evoke.

    And the media hubbub rather misses the point. What needs to change in the product is the recipe. Those crackers are 75% net carb. The current ingredients list may contain only 5 minority items safe for routine human consumption: baking soda, salt, niacin, B1 and B2.

    Here’s the list: Unbleached Enriched Flour (Wheat Flour, Niacin, Reduced Iron, Thiamine Mononitrate Vitamin B1, Riboflavin Vitamin B2, Folic Acid), Sugar, Soybean And/Or Canola Oil, Yellow Corn Flour, Dextrose, Fructose, Calcium Carbonate (Source Of Calcium), Baking Soda, Soy Lecithin, Salt, Natural Flavor, Artificial Flavor.

  5. Interesting about the opium for teething kids. Growing up in a rural part of the country as a child I remember that Paregoric was widely used for teething infants. Wikipedia says it is 4 percent opium. Also, my own mother was saved from death in childbirth with me because the old country doc gave her castor oil to induce labor quickly as she was experiencing toxemia and could have died. (no C sections available then), and it worked. Tough labor but both of us survived and she is still living well at 85. So I wouldn’t be quite so quick to dismiss all those remedies. They may seem barbaric to us now, but they had their place. People used what they had to get by and they knew they weren’t always the best but here we are in part BECAUSE of them.

  6. The article about not eating everything in moderation sounded promising until I read the recommendation of what to eat. “The researchers recommend eating more plant-based foods, which includes fruit, beans, vegetables and whole grains. Additionally, they recommend adding low-fat dairy products, nuts, poultry, fish and vegetable oils to your diet. ” What else is new?

    1. Don’t forget, it’s also a good idea to avoid red meat as it’s more “problematic” than whole grains and vegetable oils…

    2. Yes, Time Traveler, I got to that point too, but I have wondered how diverse I really need to be. So, it’s like the initial question was valid but then they switched ideas mid-article and trailed off into other (pat) ideas.

  7. It seems to me that the Lancet study leaves open some important questions.

    1. What was the overall carb intake of the various groups? If all groups consumed equal amounts of carbs before adding (or not) alcohol, then we’d need to separate the influence of alcohol from that of the additional carbs. Without going through each permutation, I think there would be interesting answers no matter what the intakes were.

    2. We know that alcohol affects the brain. Aside from morbidity, does it cause permanent changes to the brain? Are these changes good or bad?

    3. What about the impact of alcohol on reproduction? Does it change sperm or egg cells in some way, good or bad?

  8. I’ve read that fasting is just as good an m-tor inhibitor as rapamycin and has none of the side effects

  9. I LOVE the ancient DNA story, and so happy for your recommendation earlier this year re the Insight podcast. Both great for anyone interested in DNA & deep human history.