Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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January 07 2018

Weekend Link Love — Edition 485

By Mark Sisson
24 Comments

weekend_linklove in-lineResearch of the Week

Obese or overweight black people with vitamin deficiencies who took 4000 IUs of vitamin D—six times the recommended dose—saw rapid reductions in arterial stiffness.

Some people are immune to CRISPR gene modification.

Acetaldehyde, a toxic metabolite of alcohol, damages the DNA of stem cells.

A genetic predisposition toward greater insulin responses increases the risk of obesity.

New Primal Blueprint Podcasts


Episode 207: Mark Sisson and Robb Wolf: I get together with Robb to answer some listener questions and talk about what we’ve been up to.

Each week, select Mark’s Daily Apple blog posts are prepared as Primal Blueprint Podcasts. Need to catch up on reading, but don’t have the time? Prefer to listen to articles while on the go? Check out the new blog post podcasts below, and subscribe to the Primal Blueprint Podcast here so you never miss an episode.

Interesting Blog Posts

What’s the evolutionary purpose of gods?

The epigenetic power of postnatal contact. Or, why you should touch, nurse, carry, and wear your babies.

Media, Schmedia

Yet again, the best diets get ranked last in this year’s “Best Diets” list.

People in San Francisco are spending almost $40 for 2.5 gallons of untreated, unfiltered “raw” water.

Everything Else

You might remember the story of Leafy, the little girl who went keto to successfully treat her seizures. Now her parents want to help other families discover the power of food as medicine, and they need your help.

Florida man fills car with frozen iguanas, car warms up, iguanas come back to life and crash the car.

Any Lovecraft fans?

Just imagine this dementia treatment using virtual reality.

Fishing trip.

Here’s why the Chinese are so into drinking hot water.

Things I’m Up to and Interested In

Food I should eat more of: Mushrooms.

Sure would be nice to have: The gene variant that protects against Alzheimer’s even in the presence of other established genetic risk factors.

Article I’m pondering: The case for thinking of death as a process.

Fact I was surprised (and pleased) to learn: 40% of Hong Kong consists of nature preserves and county parks.

News I didn’t enjoy: Chocolate is set to go extinct in 40 years.

Recipe Corner

  • Go bigos or go home.
  • Make-ahead breakfasts are often the only way people these days can eat in the mornings. This chorizo frittata is a great example.

Time Capsule

One year ago (Jan 7– Jan 13)

Comment of the Week

I’m going to start by using proper grammar to live awesomely.

– You’re doing good so far, George P. Burdell.

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24 thoughts on “Weekend Link Love — Edition 485”

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  1. As I’m across the Bay from the rich tech-bros in San Fran, I shall start bottling the magical healing waters of Lake Merritt. DM me for shipping quotes

  2. I am amazed that Weight Watchers scored so high on the list of best diets. I’ve never known anyone who lost weight with Weight Watchers that didn’t put it all right back on again, and then some. Same for Jenny Craig and the like. The attitude always seems to be, “I’ll be glad when I lose this last 5 pounds so I can go back to eating whatever I want.”

    There’s probably nothing inherently wrong with a Dash or Mediterranean approach to eating if one does okay on grains. Problem is, most people don’t do okay. Certainly the infamous US food pyramid–with its 11 or so recommended daily servings of grain products–never did anyone much good. Also, the whole idea of messing around with points, exchanges, counting calories, etc. really turns me off. Obsessing over numbers is not something I care to bother with when it comes to food.

    I’m not surprised that the keto diet made the bottom of the list. It’s a medical diet that has become a fad. A few diehards might find it sustainable, but for most of us it’s way too restrictive to adopt as a permanent lifestyle–particularly when a healthy whole food Paleo approach accomplishes the same thing.

      1. Glad to hear that, Leigh. Keto does help a lot of people, usually on a temporary basis. It doesn’t work well for most of us with respect to being a permanent way to eat and live.

      2. Same here. I do not respond well to any amount of carbohydrates. Keto, with fairly long periods of straight-up carnivory, keeps me from completely detailing my health. The only reason it isn’t considered sustainable is that there is always a line of people telling you it isn’t sustainable or that it’ll kill you.
        I’ve found a permanent way to feel awesome, and social pressure will not change that.

      3. Glad to see keto has helped you, Leigh. My brother and I, on the other hand, did not respond well to the extremely low carbohydrate intake of keto. We both do better on a low-to-moderate-carb range (100-150g/day).

        Everyone is different.

    1. I wonder if Weight Watchers is one of the site’s advertisers. That can make a big difference in their ranking.

      Weight Watchers could not help me find healthy alternatives to the dairy, wheat, and legumes I have to avoid because of food allergies. Paleo/Primal/Low-to-No-Grain gives me a blueprint for eating healthy and avoid some of my food allergies (it doesn’t steer me clear of the cashew, pistachio, grape, or melon allergies, but I can work around those).

  3. Yes, the fans are here 🙂

    Ph’nglui mglw’nafh Cthulhu R’lyeh wgah-nagl fhtagn

    “In his house at R’lyeh dead Cthulhu waits dreaming.”

  4. Circumcision interrupts bonding and introduces pain and violence to a mind just hours hold. Ain’t that a nice lesson to learn right out of the chute, and yes, it does affect behavior. The research is clear. Circumcision is a barbaric habit and sexual assault. Prosecuted.

  5. The purpose of gods? To posit the ideal for man to aim for. And the bad guys? What not to be.

  6. Those iguanas are no joke. My daughter was bitten by one a few years ago in Mexico. I would steer clear even if they did fall out of a tree! And completely horrified by the thought of chocolate going extinct. I eat a little dark chocolate almost every day.

    1. Supply and demand will ensure it won’t go extinct. It just may cost $50 a bar.

  7. I was very surprised when I read “There are currently no interventions for Alzheimer’s disease” Prevention being one of these. I was under the impression that cutting out wheat and grains was a factor in in preventing Alzheimer’s. I am always surprised by how many highly intelligent people end up with the disease as it is suggested that keeping the brain active will help.

  8. Obviously, the Mars company is not aware of the 11th commandment: THOUGH SHALL NOT GENETICALLY MODIFY CHOCOLATE.

  9. Florida Man: not the hero we need, but the one we follow out of morbid curiosity.

  10. Mushrooms. They have another very interesting trait. They are an aromatase (an enzyme) inhibitor, a very effective one. Why does this matter? Well, aromatase converts hard won, valuable testosterone in men to estrodial, precursor to estrogen. Grrrrr. Yeah, we all talk about increasing, T, but what about stopping the T leak that is aromatase?

    So, as a kinda old guy interested in “men’s health” issues with a beautiful 20 year younger fiance, these things matter, ya know? Here’s a Bing search on the topic, you can see that this is not a Dr. Oz Shill Of The Week. https://www.bing.com/search?q=mushrooms+%22aromatase+inhibitor%22&pc=MOZI&form=MOZSBR

    What I do is buy a couple of pounds of sliced button mushrooms, put them on parchment paper (they stick to metal), and dry in the over at 200 degrees until very dry. Then I powder them in the blender.

    A teaspoon of the powder is the equivalent of eating 1.4 ounces of raw mushroom. Add to anything you want, especially salsas, on eggs, incredible in hamburgers, smoothies, whatever. Simply, you can’t go wrong.

    Of the many rabbit holes I’ve gone down to reverse age declination of testosterone, I swear that this one has made a noticeable difference, dose dependent.

    Ask Kirsten……………