January 31 2016

Weekend Link Love – Edition 385

By Mark Sisson

Weekend Link Love

I had a great time on the Joe Rogan Experience podcast. Give it a listen.

Two cool pieces of Primal Blueprint Publishing news:

  1. A recent paper on hidradenitis suppurativa, the mysterious skin disorder and subject of Tara Grant’s The Hidden Plague: A Field Guide for Surviving and Overcoming Hidradenitis Suppurativa, mentioned Tara’s work on the dietary etiology of HS favorably.
  2. Tara will be speaking about hidradenitis suppurativa at the 74th Annual Meeting of the American Academy of Dermatology in early March.

Congratulations, Tara!

Research of the Week

Vegetarians and omnivores have similar mortality rates.

Putting standing desks in schools reduces time spent sitting, using screens, and even watching TV.

The New England Journal of Medicine explains why it opposes data sharing: “a new class of research person will emerge—people who had nothing to do with the design and execution of the study but use another group’s data for their own ends, possibly stealing from the research productivity planned by the data gatherers, or even use the data to try to disprove what the original investigators had posited.” Nope, wouldn’t want actual science happening!

People who value time over money are happier.

Two years on a paleo diet had a “significant and persistent” positive effect on liver fat.

New Primal Blueprint Podcasts


Episode 104: Simon Whitfield: Host Brad Kearns sits down with Simon Whitfield, world-famous Olympic triathlete, and Andrew MacNaughton, one of the greatest triathlon coaches in the world to discuss peak performance, the importance of lifelong learning, why an internal positive narrative is so necessary, the danger of getting too full of oneself, the restorative beauty of standup paddling, and much more.

Each week, select Mark’s Daily Apple blog posts are prepared as Primal Blueprint Podcasts. Need to catch up on reading, but don’t have the time? Prefer to listen to articles while on the go? Check out the new blog post podcasts below, and subscribe to the Primal Blueprint Podcast here so you never miss an episode.

Interesting Blog Posts

More bad news for statins (and statin-takers).

How “natural geoengineering” through re-introduction of animals and their predators into their respective ecosystems can counter climate change.

Muscle really is the key to healthy aging; just check out those MRI pics!

Media, Schmedia

Katy Bowman’s furniture-free home.

Elite sports teams are experimenting with higher-dose vitamin D supplementation.

Everything Else

A random dog casually placed 7th in a half-marathon without even trying. The dog, “lazy” according to its owner, beat almost everyone else despite taking frequent detours to inspect dead rabbits and sniff other dog butts.

Can viewing your brain in real time treat anxiety and depression?

When life gives you lemons, snowboard through Times Square.

A type of medicinal clay traditionally used by British Columbia’s Heiltsuk First Nation people has potent antibacterial activity against drug-resistant bacteria.

We’re catching way more fish than we think.

How to de-seed a pomegranate with a salad spinner and shuck clams quickly and cleanly.

Recipe Corner

Time Capsule

One year ago (Feb 2 – Feb 8)

Pic of the Week

Image of the Week

Comment of the Week

“Hey Dr. Oz, we booked Dr. Peter Attia to talk about the new outlook on saturated fats in the diet!”

“Great job team, he is a wealth of information on the topic. Let’s have him roll a bunch of balls down a stupid ramp to demonstrate the difference between small and large particle LDL! That’s a great use of our time with him!

– Legitimate laughter was had.

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21 thoughts on “Weekend Link Love – Edition 385”

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  1. Loved the Katy Bowman article. She is so cool! When I have to sit, I sit on the floor as much as
    possible. And when I get up I try to do so without using my hands or knees????

  2. Re: Joe Rogan, when you talked about why you think the longevity effect of wine isn’t well established, I think you should’ve cited Prof David Nutt:

    Physiologically, alcohol’s benefits have never been proven, but the idea that low levels of drinking are protective is a pervasive myth – and a very useful one for the industry. We know that, for a particular group of people (middle-aged men), those who drink small amounts, particularly of red wine, have slightly lower levels of heart disease than those who don’t drink at all. However, this may be because this group has more healthy lifestyles, or because of the “sick teetotaller effect” – where many people give up alcohol because they are ill (perhaps from some other disease); their worse health outcomes may have nothing to do with whether or not they drink, but do make the health statistics of non-drinkers appear worse. To know for sure if alcohol is actually preventing heart disease, we would need to do a randomized trial where some of this group drink no alcohol, others drink it in small amounts and others drink more heavily. Until this experiment has been done we don’t have proof that alcohol has health benefits.

  3. Mark, you never cease to impress me. You’re this generations Jack LaLanne and I’m stoked you brought your message to another large audience. Rogan is a passionate person and I’m off to listen. (Now if we can get Tom Woods with Joe Rogan…)

  4. Karrington Moudry-Cooper, CNC wrote on December 17th, 2015:

    “Mark, have you ever considered being a guest on the Joe Rogan Experience podcast? I think you’d fit in perfectly, as a lot people in your world have been on there (Robb Wolf, Dave Asprey, Dennis McKenna (brother of Terence), ect…) Plus Joe lives right down the street from you in L.A. (another Hint, Hint..)”

    This makes me very happy 🙂

  5. Ludivine. LOL. just goes to show ya, slow and easy training wins the race. I had a really good laugh. thank you.

  6. Way to go Tara,

    Thank you Mark for helping her, and giving her a platform to launch from.

    Tara’s book helped me immensely with my condition.
    I had doctors etc. tell me all kinds of nonsense that just made me feel like I was dirty and there was no hope. Not very helpful when you’re sick and depressed.
    I’m so glad she is educating them to recogize firstly what it is, and secondly how to treat it.
    If any of you are suffering with this, read her book stat!

    Many thanks again to Tara for improving the quality of my life.

    I was sad to read that Tara lost her house in the Cobb mountain fire recently, I live fairly close by and the fire looked like a volcano from my vantage point.

    I hope you’re doing well Tara and getting your housing and life back in order.

    Big Hugs and Roses to You,


  7. Awesome podcast with Joe Rogan, I hope he gives primal a good shot. I was wondering if you could go into more detail about not refilling glycogen in the muscles after working-out to take advantage of gh production. Thanks 🙂

  8. Hey Mark loved your appearance on the JRE.
    Learnt so much from your audiobooks, your not too sharp on the ears and I sense your passion in most issues of conventional eating vs primal.
    What’s the most and recommended grams of carbs you should have in one sitting?
    Thankyou for redesigning the way I’m going to live awesome from here on out!

  9. “The New England Journal of Medicine explains why it opposes data sharing…”

    No, in fact the editorial linked to comes down in favor of data sharing. The Journal’s piece was a bit clumsily written (and that part about “disprov[ing] what the original investigators had posited” in particular could have been handled better), but here’s a little more context to clear things up:

    “A second concern held by some is that a new class of research person will emerge — people who had nothing to do with the design and execution of the study but use another group’s data for their own ends, possibly stealing from the research productivity planned by the data gatherers, or even use the data to try to disprove what the original investigators had posited. There is concern among some front-line researchers that the system will be taken over by what some researchers have characterized as ‘research parasites.’

    “This issue of the Journal offers a product of data sharing that is exactly the opposite…”

  10. Mark, I’m dying to know your view on SOYLENT, a new 400 cal ‘meal’ in a jug, that’s meant to provide well rounded nutritious ingredients. Looks like processed, non-primal food to me, with some fancy branding…..?

  11. Long time reader, first time commenter, but wanted to address the data sharing issue discussed in the New England Journal of Medicine. I fully support data sharing requirements, but there is certainly a legitimate argument to the contrary, that does not involve greed.

    First, different research projects have vastly different durations, but grant cycles are typically all pretty similar. Hiring and promotion committees look at publication records to make decisions, and projects of longer duration generally do not produce the number of publications that these committees appreciate, especially for young investigators. As such, there is already a strong incentive to do shorter, less informative studies.

    A successful long term study must result in multiple publications. Due to funding, these publications cannot all come out at the end of the study. Some results must be brought out earlier in the process, before all aspects of the data can be analyzed. If data sharing is forced, other groups will analyze this data, and publish the results before the group that had generated the data. Once this happens, these results cannot be published by the group that generated the data, because the analysis and conclusions have already been published.

    In our current system this is career suicide for the investigator, and the investigator will inevitably choose to do the types of shorter studies that MDA readers routinely complain about. Pass out questionnaires. See how much cholesterol, refined carbs and o6 can be pumped into a mouse. etc. This prevents good science from happening, and until the system is revamped to the very top, some investigators will need to publish in journals that do not have data sharing requirements, or else find other work.

    1. Thanks for the thoughtful follow-up on the data sharing issue. As you show, it’s not as clear-cut as MDA’s snarky treatment would suggest.

      Unfortunately, MDA has badly misrepresented the issue not only in spirit but in fact as well. As I showed above, the article linked to did not even oppose data sharing in the first place. In addition, the Journal published the following a few days after the original article (full reprint below):

      “the Journal is committed to data sharing in the setting of clinical trials”

      Given its commitment to truth, health, and science, I hope that MDA will publish a correction as soon as possible.

      Full reprint of the Journal’s data sharing follow-up:

      “We want to clarify, given recent concern about our policy, that the Journal is committed to data sharing in the setting of clinical trials. As stated in the Institute of Medicine report from the committee on which I served and the recent editorial by the International Committee of Medical Journal Editors (ICMJE), we believe there is a moral obligation to the people who volunteer to participate in these trials to ensure that their data are widely and responsibly used. Journal policy will therefore follow that outlined in the ICMJE editorial and the IOM report: when appropriate systems are in place, we will require a commitment from authors to make available the data that underlie the reported results of their work within 6 months after we publish them.

      “In the process of formulating our policy, we spoke to clinical trialists around the world. Many were concerned that data sharing would require them to commit scarce resources with little direct benefit. Some of them spoke pejoratively in describing data scientists who analyze the data of others. To make data sharing successful, it is important to acknowledge and air those concerns. In our view, however, researchers who analyze data collected by others can substantially improve human health.

      “We need your help to move medicine forward and improve patient care. Our enemy is disease. By working in collaboration, as we have suggested, biologists, data scientists, and clinical trialists can advance the art, and everyone will gain. Clinical trial data are some of the highest quality data in medicine. They should be used responsibly and extensively to help alleviate suffering. We believe that we will all benefit most if this is done collaboratively, but the Journal’s data sharing policy will apply in all settings.”


      1. I still think the original editorial was problematic, even in light of the follow-up.

        It refers to scientists who use others’ data as “research parasites,” and it only supports “symbiotic” data-sharing—data-sharing done in concert with the original authors. So-called “parasitic” data-sharing, or reanalysis with the outcome and/or intent of refuting the original research, is just as important for free and honest science.

        You’d be hard pressed finding original authors who will collaborate on research that refutes their own research. It still needs to happen.

        1. We’re in agreement that the original editorial is problematic. But the fact remains that MDA introduced the item by claiming that “[t]he New England Journal of Medicine explains why it opposes data sharing” when in fact the Journal does no such thing. And the fact remains that the quote MDA pulled was taken wildly out of context. A correction is in order.

  12. Another useless “vegetarians and omnivores mortality” study

    …more interesting would be to see them compared to vegans: most vegeterians compansate the lack of meat with diary products and eggs/fish/tofu – another sources of bad proteins and toxins

  13. Sometimes the Universe just lines things up. I’ve been listening to the Joe Rogan Experience (JRE) since the beginning. Joe is one of my heroes on how to live with passion and purpose. I’ve been dabbling in Primal eating for about a year now, even if I didn’t call it that. I found MDA about 2 months ago and it has quickly become my first stop to “Google” things health related (I just researched seaweed this morning and didn’t need to leave MDA…a wealth of info was had !). Anyway, I was listening to an episode of JRE and he announced that he would have Mark Sisson on his next episode. I’m sure I would have looked up this blog and picked up Mark’s books after listening either way, but it was oddly comforting that someone I respect like Joe was also seeking knowledge and truth from someone like Mark. It was one of those moments where two of your worlds collide….like two of your good friends meeting each other. I look forward to learning more from Mark and this community. Currently reading Primal Blueprint and slowly getting my wife and family on board as well.

    It’s been a month since I really “dialed it in” and I feel great. I’ve lost 20+ lbs (it’s slowed to about 2 lbs a week but I was astonished that first couple weeks even if it was water and loss if inflammation) and I am thinking clearer, better mood, etc etc…most of you know. This post ended up longer than I wanted…but I haven’t been this passionate about a health and diet related subject in a long time even though I am a long-time student of health and nutrition. I always read some of the comments on each post and I hope to join the conversation.

  14. The statin piece is interesting. Commenter Bob Niland brought up the issue of those with hereditary lipid problems, but I haven’t seen any useful answers there so far. Anyone here care to comment?

    I had fairly good results in terms of blood test markers using full flush niacin. But it made me lightheaded and nauseous (besides the flushing), and sometimes resulted in spending up to about 5 hours of my day feeling unwell (due to twice per day dosing). I’d like to hear what other alternatives folks have tried.

  15. I found you through the Joe Rogan Experience. What an outstanding podcast and what an eye opener. I have several of your books including The Primal Blueprint and the 21 Day Challenge books in route as we speak. I look forward to immersing myself in this new data and have high hopes for my future health and well being. Thanks for everything you do.