Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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July 08 2012

Weekend Link Love – Edition 197

By Mark Sisson
40 Comments

How a kind of bacteria carried by pet dogs can protect you from asthma. And no, this doesn’t mean you have to French kiss your pet to get the effect.

In a recent study, short, 8-second bursts of cycling sprints reduced belly fat in overweight men. They added muscle, too.

Why both diet and exercise are vitally important: calorie restriction for life extension doesn’t work very well without concomitant physical activity.

Glucose deprivation activates a feedback loop that kills cancer cells. Hmm, now how would one go about depriving one’s cancerous cells of glucose?

For all you fat-adapted readers out there: adding sprint intervals to low level cardio increased glycogen depletion without lowering fat oxidation or increasing hunger. Win-win-win!

If you’re gonna stretch before a workout, dynamic beats the pants off static. Here’s why.

How protein satiates.

A Facebook Group called Paleo Nursing Donors has been created by paleo-enthusiast Rachel Huizenga Jennings that is “dedicated to helping babies in need of grain, legume, and dairy free breastmilk find donors. There are many babies with special needs who can benefit from milk donations made by a Mom on a paleo diet!”

Strawberry season isn’t for much longer (at least in California). Here’s yet another reason to take advantage of it.

Recipe Corner

Time Capsule

One year ago (July 8 – July 14)

Comment of the Week

Vegans and PB followers might both wear Vibrams but there are other distinguishing characteristics.if they look like the person working in the health food store, they are probably vegan. If they look tanned, buff, and vibrant they are most likely Primal.

– Well said, Dave.

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40 thoughts on “Weekend Link Love – Edition 197”

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  1. Very interested in the asthma research. The key in getting rid of my own asthma came down to giving up grains and dairy.

    1. For me it was walking a lot and sleeping on a firm surface (without mattress). Some research suggests that also intermittent fasting can help some.

    2. Agreed. I was on Sadvair for two years until we went Paleo/Primal. I can have a rare beer, but just one. Any more wheat/grains than that and I’m wheezing myself to sleep. But that’s Ok, there are so many other wonderful natural things to eat such as the two gigantic buckets of organic blueberries the wife and I picked this weekend. Half will be dried for pemmican and snacks and the other half frozen. (maybe some blueberry mead?)

      -Tim

  2. I just picked ten pounds of strawberries yesterday, hmmm!!! Good news, besides the fat-phobia in the piece.

  3. Will starving cancer cells of glucose be a potential treatment for cancer? or will the american public finally understand that its the glucose that is giving us the cancer in the first place? So interesting.

    Also, How does one “starve” cells of glucose? Doesn’t our body produce its own glucose?

    1. Our brains use a certain amount of glucose a day. (That’s why we produce it.) I think the massively excessive glucose is the problem.

      1. Yah, that’s sort of what I was thinking also. Wanted to see if anyone could come up with a really sciency answer

      2. I forgot where, but I read that the brain will happily adapt to using ketones for up to 60% of its functioning.

    2. Max,

      The researchers mention potential use for this discovery in treating cancer: “In addition, the authors showed the possibility of exploiting this positive feedback loop for therapeutic intervention. Combining short-term glucose deprivation with an inhibitor of tyrosine phosphatases, they demonstrated synergistic cell death in a cancer cell line.”

      It seems that an obvious implication of this study is for cancer patients to eat a low-carb diet. The question that occurred to me was “Does lowering consumption of glucose inhibit cancer?” That’s a much tougher question to answer. Cancer has so many contributing factors that it might be impossible to even design, much less fund and carry out, a clinical trial to test this idea.

      1. Does lowering consumption of glucose, lower the concentration of blood glucose? Fruitarians claim the opposite.
        Is there any evidence on either side?
        That is, is there any evidence that with two healthy diets, the one with more glucose increases leads to the highest blood sugar?

        We would get mad if someone simply assumed that eating fat directly leads to clogged arteries.

        1. We totally WOULD get about that! What a great question. I’d love to see some research on this too.

    3. I’m sure some enterprising pharma company is working on a drug that will do this as we type….

  4. If they have a fine downy growth of hair on their face and smell of pickles they are probably vegan. What’s up with that?

    1. humans have fine downy hair growth when we are starving. i can’t help you with the pickle aroma thing, although i’m sure it’s related to the whole starving thing.

  5. Mark, all of your links dovetail perfectly with my current passions! And thank you for being such a kick-ass summarizer. Your validation of my lifestyle is so refreshing, like a fresh wet dog tongue!

  6. Otto Warburg must be spinning in his grave. Eighty years after his Nobel Prize, we read “Now, in a unique study, a UCLA research team…” investigates the effect of glucose deprivation on cancer cells.

    A small consolation to many of us.

  7. Those pork skin noodles sound brilliant!!!

    I must get to a butcher at once!

  8. According to DR Sardi, avoiding excess sugar in our diets, and chelating to remove excess iron from our bodies is the crucial way to avoid cancer.

  9. It takes 8-10 seconds for me to sprint up the hill in our backyard, depending on if it’s the first or twentieth run. Good to know that those short bursts can be useful.

  10. Regarding the assertion “calorie restriction for life extension doesn’t work very well without concomitant physical activity.”, you could have saved us a click by adding “in fruit flied.”

  11. I am just finishing up my first 24 hour Fast. I have taken 4 BG readings during the Fast and my #’s stayed the same at 90. I’m not sure if that is good or bad but I feel great.

  12. Fasting (IF) is not only simple and fun– it saves a whole lot of scheckles!!

    I find that when I am hungry for breakfast I eat three eggs/bacon/ and coffee..then I may fast til the next morning.

    That includes hill sprints for lunch and lawn mowing for dinner (no I don’t graze on the lawn).

  13. great links! just picked up 4 lbs organic local strawberries here in the bay area…mmmmm so good dipped in coconut cream 🙂

  14. We use pork skin for a snack fairly frequently. But we crisp it up so it’s like popcorn. I will have to try the noodles. It just means I have to cook the skin a lot less to get the noodle-like consistency.

  15. This pork skin sounds delicious, so gelatinous and collagenous!

    regarding sprinting, I also notice that i am getting more fat around my arms and belly since I’m doing less interval training exercises. (I’ve been doing more yoga and less interval training.) or it could be from drinking more beer…. well in the hot summer, it’s hard to resist.. lol

  16. So, if I’m reading the sprinting article right, the sprinters lost 4 pounds of fat while gaining 2.6 pounds of muscle. That is a pretty impressive ratio, even if it was over a 3-month period.

    I know most of Mark’s stuff mentions shorter sprinting session, and generally only once a week even, but the routine in the article seems like it would be interesting to give a shot.

  17. Otto Warburg is indeed spinning in his grave. He considered both glycolysis and lipolysis to be detrimental to the functioning of the cell. In his mind, oxidative metabolism was where it’s at (skeletal muscle excluded). Cancer cells accumulate and produce estrogen, which causes hypoxia. Change the histological environment and you change the cell.

    Warburg is not on your side. The same buildup of ROS in lypolytic cancer cells is the same buildup that happens in “normal cells”. They are equally damaging to the cellular environment.

  18. Re: Sprinting study for overweight males. Forgive me if I am incorrect, but 12 seconds seems like a mighty short recovery phase considering the duration of the exercise period in the study (20 minutes). A. Not sure I could even complete 20 minutes of continued sprinting for 8 seconds with only 12 seconds recovery. That would be 60 sprints. I typically do 30 second max effort (high intensity on a bike) with 60 second recovery just fine for 12-15 min (8 to 10 cycles). B. It does sound like a good set up for hill sprints, running up and then walking down hill, but 20 minutes? Am definitely going to integrate those. D. Wouldn’t the recovery period be ineffectual since it is so short? C. Also, not sure this study really applies to either sprinting or typical interval training. Even Tabata sprints (20 second max, 10 second recovery)last only 4 minutes and a rest period is recommended between rounds. D. As an aside, I almost sent the article to a loved one, but then I realized it basically would just reinforce his full-bore, high intensity, steady state cardio for 30 to 45 minutes every day with little if any strength work. I’ve recommended he interval train, even sent many articles, but he took it to mean shorten his workout from an hour to 30 to 45 minutes and work three times as hard for the duration, every day. He likes the shorter, harder workout better, but no change in body comp. I’ll take the PB approach; results, ease, flexibility, and sanity. E. Forgive the breadth of analysis and the outline format, I am taking the California Bar in two weeks.

    1. Ignore the typos in the Outline format, I apparently added more points and didn’t renumber(letter).