Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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Tag: immune health

Primal Action Point: The Mind-Body Connection & Thyroid Health

“I became aware of the power of positive thinking after solving my first bout of hypothyroidism. So when a Reverse T3 problem showed up, I actively filled my life with audiobooks, podcast interviews, and films related to spiritual healing, the power of positive thinking, and the power of the subconscious mind.

Make a vision board to hang in your house, or make a smaller version that you can keep private if you don’t want others in the household to see it. Devote the entire vision board to health and healing; it can be a continual source of inspiration and hope while also imprinting your subconscious mind with positive health affirmations every time you see it.

If you are experiencing hypothyroidism for the first time, just know that it is fixable. You have the highest chance of success if you dedicate yourself to learning all that you can about hypothyroidism while adopting a paleo/primal eating and lifestyle strategy to support your goals.

— Excerpts from The Paleo Thyroid Solution by Elle Russ

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Introducing The Gut Healing Protocol—With a Don’t Miss Deal!

Greetings readers, as you know, gut health has become the hottest of topics in ancestral health circles, and is also getting increased attention in mainstream medicine. More and more science is validating how a healthy gut microbiome has wide-reaching impact on general health, and that a damaged gut can set you up for all kinds of downstream health challenges. There are several helpful primers on gut health published here (1, 2, 3).

Today’s message, however, is something a little different and more personal. It comes from a dynamic young health expert from Australia named Kale Brock. We are pleased to bring his wildly popular grassroots gut health book, The Gut Healing Protocol: An 8-Week, Holistic Program to Rebalance Your Microbiome, to the U.S. market. Kale became an expert on gut health not from formal medical training, but rather the hard way. Like many thought leaders in the ancestral health community, Kale’s obsession with gut health was triggered by a serious health setback that was poorly addressed by traditional medicine.

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Dear Mark: New Coffee Study, Letting a Fever Run its Course, Collagen Dosage

For today’s edition of Dear Mark, I’m answering three questions from readers. First, I give my take on a new, big coffee study, which analyzed several meta-analyses of existing coffee and health data. Second, should you let a fever run its course or try to defeat it at all costs? The body obviously “wants” to get hotter in these situations. Is there a good reason? And finally, how much glycine do people need per day?

Let’s go:

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Dear Mark: Is Keto Ancestral, Ketone Breath, and Keto for Lupus?

For today’s edition of Dear Mark, I’m answering some questions about keto (hey, you folks keep asking!). First, is being on a ketogenic diet actually congruent with our ancestry? Is there historical precedent? Next, is bad breath really a reliable indication of being in ketosis? And finally, could going keto help treat the autoimmune disease lupus?

Let’s take a look:

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More on Adaptogens: Ashwagandha, Astragalus, and Holy Basil

Last week I waded into the adaptogen theme, examining the many ins and not-so-many outs of American and Asian ginseng. It got me thinking—why not keep the ball rolling? The ginseng varieties I mentioned are only two among many adaptogens after all.

Let’s dive right in and take up three additional adaptogen choices—along with some additional suggestions for discerning the safest and most potent formulations. 

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Adaptogen Effects: American and Asian Ginseng

I’ve been using adaptogens for quite some time, but in the last year I’ve been experimenting a little more with them. You may have caught my mention of a few adaptogenic varieties in one version of my daily big ass salad (not for a flavor hit). I’ve also briefly highlighted ashwagandha and holy basil, and I’ve always been a big believer (and user) of Rhodiola rosea for normalizing stress response.

All well and good. But what’s the backstory on adaptogens? What is there to gain? And what about the other options? 

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How Your Oral Biome Influences Your Overall Health

In response to my post on oral health a few weeks ago, one reader offered a comment about the oral biome, and it’s a worthy follow-up, I’d say.

The human oral cavity is home to hundreds of microorganisms. Latest estimates place the number of bacterial species in your mouth at close to 700, with the odd fungus, protozoa and even virus thrown in for good measure. This oral microbiome isn’t a whole lot different than that of our gut, but where things get interesting is when we consider the diverse range of habitats within the mouth: teeth, tongue, cheeks, gums, tonsils. All provide different living conditions for those microorganisms that colonize them, but that diversity of habitats also encourages a diversity of species.

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The Language of Microbial Culture: Explaining Prebiotics, Probiotics, Synbiotics and Postbiotics

It’s no secret that it’s one of my favorite subjects—the burgeoning field of human gastrointestinal microbiology. I know…it’s easy to get caught up in the comparative excitement of it all.

The microbiota is familiar territory to most Primal types, but with time and research, we come to understand the nuances of the terrain a little better. New terms pop up. Novel discoveries grab our attention. Promising connections become apparent. It feels like a good day to go over a bit of the latest—to provide a little refresher for those who’ve joined us recently and most of all to offer some additional perspective on what we’re learning as studies branch into new depths. 

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5 Unconventional Ways to Extend Your Life

I’ve written about extending your life by slowing down the apparent passage of time. I’ve written about some interesting predictors—but not necessarily causes—of longevity, and the common characteristics of centenarians. Today, I’m going to describe several unconventional causal means of extending your life.

I’m talking about cold, hard days, weeks, and months. Ticks on a clock. Objective measurements of time. Not just the perception of time, although that matters too.

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How to Exercise with An Autoimmune Condition

Autoimmune diseases really throw the body for a loop. You’re attacking your own tissues. Your inflammation is sky high. What’s usually good for you—like boosting the immune system—can make it worse. You’ll often restrict eating certain foods that, on paper, appear healthy and nutrient-dense. You take nothing for granted, measure and consider everything before eating or doing it. Sometimes it feels like almost everything has the potential to be a trigger.

Is it true for exercise, too? Must people with autoimmune diseases also change how they train?

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