Tag: Keto Recipes

Monday Musings: Torcetrapib Part Deux? and Keto Diets Seize the Day

Overburdened doctors sure do love tangible targets, like lipid numbers. They’re easy to hit with drugs. There’s no guesswork – statins and the like actually do lower cholesterol (whether that’s helpful or harmful is the question) – and that makes a physician’s life simpler. Oh, sure, lifestyle changes work, but most patients won’t bother trying them (especially when the changes you prescribe are founded in faulty science and no fun following). Doctors can usually get patients to take a pill.

There’s yet another cholesterol-busting wonder drug on the coming horizon called anacetrapib. A recent eighteen-month trial found that it boosted HDL (from 40 to 101) 138% greater than placebo and slashed LDL (from 81 to 45) 40% better than placebo in patients already taking statins by hampering the effects of the CETP enzyme. Another potent CETP-inhibitor – torcetrapib – made similar headlines in 2006 when it boosted HDL and reduced LDL like nothing else before it, but those headlines were overshadowed when 60% excess mortality occurred in people taking the drug versus those on placebo. So far, anacetrapib seems safe enough, but I’m not holding my breath. I tend to get a little uneasy when we change a single variable and mess with enzymatic pathways in a very complex closed system, with a single goal (raise that HDL, drop that LDL!) in mind. Focusing on numbers that are largely an indication of your lifestyle without doing anything about the lifestyle itself is like pissing into the wind: quite often, it’ll splash all over you, and you’re lucky if it’s just the shoes.

Read More

What About a Zero Carb Diet?

Zero carb is getting (relatively) popular. A handful of valued MDA forum members eat little-to-no-carb, and several others probably imagine it’s ideal even if they don’t personally follow it. I wanted to address this because there seems to be some confusion as to how a zero carb eating plan relates to the Primal Blueprint eating plan. To begin with: I think zero carb can be a viable option for some, but highly impractical for most. If one had access to and ate different animals, all range fed and without pollutants, and if one ate all offal (and stomach contents) it’s possible to approach zero carb… but again highly impractical. If you really, really love meat and fat and offal, and get genuine enjoyment from eating nothing but meat and fat and offal, have at it. On the other hand, if you are looking for a wider variety – and gustatory enjoyment – of the foods you eat, zero carb may be unenjoyable, impractical, unnecessary, and at worst (if not done just right) downright dangerous.

Let’s take a look at just a few of the reasons why vegetables are a part of The Primal Blueprint:

Read More

Dear Mark: Glycogen

Dear Mark,

I’m trying to understand how glucose that’s created by proteins and fats is used and stored. Is that ~200g of glycogen stored in the muscles to be used for exercise, or is it stored in the liver and used to fuel the brain and “day-to-day” functions? Also, if muscle glycogen is depleted, will ingested carbohydrates be used first to replenish muscle glycogen and then to fuel other daily functions, or are they used the other way around? I’d like to be able to use ketones to fuel my daily activity, but still have enough muscle glycogen stores to fuel intense exercise.

Read More

Dear Mark: Ketosis

Dear Mark,

What are ketones? How does ketosis play into the Primal Blueprint? Did our bodies evolve to run on ketones? If not, why do they exist?

Ketones, to put it briefly, are compounds created by the body when it burns fat stores for energy. When you consume a diet very low in carbohydrates, the body responds to the significantly lowered levels of blood sugar by flipping the switch to another power source. The body converts fatty acids in the liver to ketones. Ketones, then, become the main energy source as long as blood sugar levels remain low.

Read More

Latest Posts