Resveratrol Does It Again

Seriously, how can we not love this stuff? The potent little antioxidant has been hailed for years as anti-inflammatory, anti-atherogenic and even anti-cancer. And, as for the cancer part, the news just keeps getting better. Research out of the University of Rochester Medical Center shows that resveratrol is doubly effective in treating the exceptionally problematic pancreatic cancer.

[Resveratrol] can help destroy pancreatic cancer cells by reaching to the cell’s core energy source, or mitochondria, and crippling its function. The discovery is critical because, like the cell nucleus, the mitochondria contains its own DNA and has the ability to continuously supply the cell with energy when functioning properly. Stopping the energy flow theoretically stops the cancer. …The new study also showed that when the pancreatic cancer cells were doubly assaulted — pre-treated with the antioxidant, resveratrol, and irradiated — the combination induced a type of cell death called apoptosis, an important goal of cancer therapy. In fact, the research suggests resveratrol not only reaches its intended target, injuring the nexus of malignant cells, but at the same time protects normal tissue from the harmful effects of radiation.

via Science Daily

In the words of lead author, Paul Okunieff, “Resveratrol seems to have a therapeutic gain by making tumor cells more sensitive to radiation and making normal tissue less sensitive.” Resveratrol’s sabotage of the cell’s energy flow is also especially important for chemotherapy because it decreases the cell’s ability to simply “pump” out administered chemotherapy treatment.

The results themselves are fascinating and promising for those who face the difficulty of a pancreatic cancer diagnosis. But we also found ourselves talking about the broader context of this research: the power of a natural antioxidant as a complementary therapy with a conventional treatment.

We talk a lot about the role of exercise and diet/supplementation in prevention here, which makes sense. No one wants to find themselves faced with a critical diagnosis to begin with. But there’s a whole new branch of research unfolding that hopes to harness the best of traditional medicine and nutrient potential. We hope to bring you more along this vein in the future.

In the meantime, send us your thoughts and perspectives.

Homemade Flickr Photo (CC)

Further Reading:

Resveratrol Reduces Signs of Aging

Wine Prevents Cavities

Smart Fuel: Wine

Subscribe to Mark’s Daily Apple feeds

Sponsor note:
This post was brought to you by the Damage Control Master Formula, independently proven as the most comprehensive high-potency antioxidant multivitamin available anywhere. With the highest antioxidant per dollar value and a complete anti-aging, stress, and cognition profile, the Master Formula is truly the only multivitamin supplement you will ever need. Toss out the drawers full of dozens of different supplements with questionable potency and efficacy and experience the proven Damage Control difference!

About the Author

If you'd like to add an avatar to all of your comments click here!

19 thoughts on “Resveratrol Does It Again”

Leave a Reply

Your email address will not be published. Required fields are marked *

  1. I’ll drink to that as well. I love it when something truly healthy is also a great way to indulge.

  2. Sadly, I’m probably going to have to let this great anti-oxidant be a infrequent one. I’d rather get my resveratrol from drinking wine instead of a capsule.

    But like others have also mentioned in comments on a previous post, I can’t ignore anymore that my tolerance for alcohol is so greatly reduced now. I hadn’t thought about it being due to LC, but that sounds reasonable. Unless it’s at at a party or somewhere really stimulating, one glass of wine at home in the evening will slow me down or put me to sleep on the sofa not long after dinner (& before the kitchen is cleaned up!). I really hated to think such a small amount of wine had that much effect, but now that I have gone a few weeks without wine with dinner (except some weekends), I can really see a difference. I’ve also lost just about 5 pounds from my middle section and I can’t think of any other reason for that.

  3. Muscadine grapes are very high in resveratrol, and North Carolina Duplin muscadine wine is very affordable at $7.50 a bottle at my local supermarket. A four-ounce glass leaves a mildly sweet taste on the palate after dinner.

  4. Resveratrol can help you to lead a long and healthy life so says Dr. Oz.

    Resveratrol Supplements can help you control your weight naturally
    by increasing energy, reducing cravings, and limiting your appetite.
    According to Wikipedia, Consumer Lab, an independent dietary
    supplement and over the counter products evaluation organization,
    published a report on 13 November 2007 on the popular resveratrol
    supplements. The organization reported that there exists a wide range
    in quality, dose, and price among the 13 resveratrol products
    evaluated. The actual amount of resveratrol contained in the
    different brands range from 2.2mg for Revatrol, which claimed to have
    400mg of “Red Wine Grape Complex”, to 500mg for Transmax,
    which is consistent with the amount claimed on the product’s label.
    Prices per 100mg of resveratrol ranged from less than $.30 for
    products made by, jarrow, and country life, to a high of
    $45.27 for the Revatrol brand. None of the products tested were found
    to have significant levels of heavy metals or other contaminants.

  5. Nancy, I’m envious.. it seems wine is a lot cheaper everywhere in Europe. In Germany I could get a good S. African red wine for about 5 euro, the same bottle is $10-15 in the USA.

  6. I am definetly interested in this superior product but without the alcohol. To actually achieve the results they are talking about, you would need to consume a 1000 bottles of red wine a day. Impossible, right? So check out this website and you can find resveratrol here in its best consumable form.
    health & nutrition, find Isotonix Resveratrol.

  7. The allometric scaling of metabolism models all the results obtained, and the reason for and limitations of caloric restriction’s effects on longevity. It is based upon the electrochemistry and thermodynamics of organic bonds of biomass. It also suggests extant ideas about mitochondrial energy generation and oxidants is preposterous, and that oxidative stress is not an issue in aging, that at the cellular level and smaller oxygen is not an electron donor,but instead an electron acceptor. That means no oxidation, but instead the generation of hydrogen peroxide, the creation of hydrogen and peptide bonds. This is about energy, not chemistry. And it bears upon the difference between basal and field metabolic rate. Resveratrol’s effects might work in a petri dish or on a lab rat, but they are harmful for large mammal, especially humans.