Dear Mark: Primal Blueprint Superiority?

Dear Mark,

If you’ll bear with me for 4 paragraphs, I’ll get to the question which is the purpose of this email!

My name is Greg, and I’ve followed your blog for a few months now. I’m grateful for the knowledge you’ve shared about nutrition. Thanks to you, I’ve eliminated virtually all white flour and processed sugar from my diet, and I’ve dramatically reduced my intake of carbs. I’m still relatively indiscriminate with fruits and dairy, so I wouldn’t say I’m a Blueprinter yet, but I’m significantly closer than when I first started reading your posts.

I came to your site with no “symptoms” from my previous lifestyle. I wasn’t carrying excess weight, my sugar intake wasn’t egregious, and I was a pretty fit 40-year old. Having said that, I was open to challenging my “default” food choices, and some of my fellow CrossFitters swore they saw performance gains after going Caveman (along with Paleo and Atkins).

My only reservation about the Blueprint was – and still is – the science. It’s not that I don’t appreciate the enormous lengths you’ve gone to base your system on above-board studies and peer reviewed literature. (I’m deeply impressed by the education you’ve amassed on your own.) It’s more that I wonder whether current science is sophisticated enough to unlock the potentially nuanced relationship between our bodies and our food. Yes, transfats are poison. And processed foods are certainly less nutritious/more harmful than whole foods. (Although no one seems to have a problem with supplements, which aren’t “whole”…)

But have we really unlocked the secret of how the body is “ideally” fueled? And is there only one answer? I don’t think so – but I do know that people thirst for the assurance that they are following “the one true way”. To me, that explains why certain diets attract cult/religious-like followings. For example, my wife works with people who swear by the blood-type diet. That’s absurd, right? But so is the literal narrative behind most religions – and that doesn’t stop people from having faith. As long as there’s no irrefutable way to isolate dietary choices from the myriad of other variables that affect a test population’s health, people will develop all sorts of (flawed) theories and support them with incomplete/misleading research. (I know how much that bugs you – since you love to tear apart poorly executed “academic” studies and papers.)

And this (finally!) brings me to my question: Why aren’t Italians all dying at 57? To be less cute: if the Blueprint is definitively superior to other modes of eating, why don’t we see populations that eat high levels of wheat-based carbs falling prey to illness and/or early death? We could single out Italians, Chinese (with their gluten), or many other long-thriving cultures that don’t eat Primal. My (totally unproven) hypothesis is that multiple foods interact with our system in ways we don’t fully comprehend. Maybe the dangers of that first plate of penne are counter-acted by the traditional second plate of animal protein. Or maybe it’s the salad, wine, olive oil, etc…

Anyway, I’m really interested in your reaction. (I’m not Italian, so don’t worry about insulting penne!) I find your Grok narrative/metaphor to be a very appealing and seemingly intuitive model for making food choices. But I can’t quite square that with counter-indicating models that don’t seem to be suffering from their “Grok ignorance”.

Thanks again for sharing your knowledge. I really appreciate the thoughtful and valuable contributions you make to this field of study.

Best regards,


Los Angeles, CA



1) There is no right answer – only choices. I just want to know the ramifications of my choices. That’s what drives me to look further.

2) Whether you eat Primally or Vegan, Mediterranean or SAD, you’ll still probably live a relatively long, relatively healthy life if you exercise. 80 years or 100. Who’s counting? The rest is more about nuances and small percentage changes in overall risk factors. Oh, and lean mass.

3) Italians may not eat as much pasta as you think (or as Italian Americans eat), they may eat more olive oil and healthy animal fats, they may walk more, they may handle stress better as a culture. Chinese don’t eat as much rice as you think. They eat a ton of vegetables and a fair amount of animal products. Having said that, they may both have a large percentage that react poorly to gluten, but who don’t report it. Who knows?

4) Anyone (including me) can find some research that supports their theory. Science is always full of holes. I love poking holes in other peoples’ science. Especially the China Study. Eat Right 4 was a neat concept that had no basis in reality after about 200 years ago. But it caught on with a bunch of people. Sometimes the scientists are so close to the method that they miss the big picture. Sadly, most of those who do the focused studies are not real visionaries. They are almost mutually exclusive concepts.

5) So MDA is my opportunity to put it all out there and see what people think. I may not be right (I think I am, though), but few people are in a position like me to combine solid experiences in endurance training, coaching, nutrition, research, drug-testing, supplement design and writing…and then synthesize those all into a world-view that makes pretty good sense in the context of evolution.

Take what you like from our posts, comment when you have a chance, disregard whatever doesn’t resonate with you, and tell your friends about MDA!!



I’d love to hear your thoughts on this, readers. Hit me up with a comment in the board!

Further Reading:

Dear Mark: Don’t Call It a Diet

Dear Mark: Ketosis

Dear Mark: Pondering Protein

About the Author

Mark Sisson is the founder of Mark’s Daily Apple, godfather to the Primal food and lifestyle movement, and the New York Times bestselling author of The Keto Reset Diet. His latest book is Keto for Life, where he discusses how he combines the keto diet with a Primal lifestyle for optimal health and longevity. Mark is the author of numerous other books as well, including The Primal Blueprint, which was credited with turbocharging the growth of the primal/paleo movement back in 2009. After spending three decades researching and educating folks on why food is the key component to achieving and maintaining optimal wellness, Mark launched Primal Kitchen, a real-food company that creates Primal/paleo, keto, and Whole30-friendly kitchen staples.

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