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16 Things That Affect Your Gut Bacteria

June 25 2014 - A couple months ago, we explored many of the ways our gut bacteria affect us, focusing on the lesser known effects like anti-nutrient nullification, vitamin manufacture, and neurotransmitter productio...

The Language of Microbial Culture: Explaining Prebiotics, Probiotics, Synbiotics and Postbiotics

May 02 2017 - It's no secret that it's one of my favorite subjects—the burgeoning field of human gastrointestinal microbiology. I know...it’s easy to get caught up in the comparative excitement of it all. Th...

Dear Mark: Ketosis and Cancer, Probiotic Dosing Patterns

September 07 2015 - For today's edition of Dear Mark, I'm answering two questions. First up, is the ketogenic diet an effective cancer treatment? There's a lot of hype in the media and online world about ketosis, but wha...

Doctors as Middlemen?: Direct-to-Consumer Online Testing Services and Other Consumer Health Trends

January 18 2011 - An alarming new health trend has medical professionals scurrying around issuing dire warnings of impending doom and death. As a recent piece in the Wall Street Journal relays, consumers are taking the...

I Am Finally on the Right Path to Optimum Health and Happiness

February 22 2013 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

What to Do About Maskne

March 03 2021 - Pandemic life comes with a lot of things to deal with that we've never had to think about before. One of those things is "maskne," or acne around the mouth and nose caused by wearing masks for prolong...

How Bad is Peanut Butter, Really?

May 17 2012 - Man, you guys really love your peanut butter. I get at least one email a week from a devoted reader of the blog who just can't shake the desire (that feels like a need) to eat peanut butter on a re...

6 Food Additives That Might Be Giving You Trouble

September 28 2021 - What’s a person to do when they’ve eliminated all the big allergens—gluten, dairy, eggs, nuts—and they’re still having mysterious symptoms that seem to be aggravated by their diet? Maybe you...

New Findings: The Link Between Cancer and Exercise

December 06 2008 - Lance Armstrong has always been seen as the exception, rather than the rule. Conventional wisdom told us that he succeeded in spite of his cancer; that exercise is the realm of the healthy, rather tha...

Heritage Turkey and Mashed Parsnips

November 10 2019 - Thanksgiving is only a couple weeks away and in the United States this means one thing: turkey. Few other foods seem to dominate a holiday like this bird with a mind-boggling demand of 45+ million tur...

16 Things That Affect Your Gut Bacteria

June 25 2014 - A couple months ago, we explored many of the ways our gut bacteria affect us, focusing on the lesser known effects like anti-nutrient nullification, vitamin manufacture, and neurotransmitter productio...

The Language of Microbial Culture: Explaining Prebiotics, Probiotics, Synbiotics and Postbiotics

May 02 2017 - It's no secret that it's one of my favorite subjects—the burgeoning field of human gastrointestinal microbiology. I know...it’s easy to get caught up in the comparative excitement of it all. Th...

Dear Mark: Ketosis and Cancer, Probiotic Dosing Patterns

September 07 2015 - For today's edition of Dear Mark, I'm answering two questions. First up, is the ketogenic diet an effective cancer treatment? There's a lot of hype in the media and online world about ketosis, but wha...

How Bad is Peanut Butter, Really?

May 17 2012 - Man, you guys really love your peanut butter. I get at least one email a week from a devoted reader of the blog who just can't shake the desire (that feels like a need) to eat peanut butter on a re...

6 Food Additives That Might Be Giving You Trouble

September 28 2021 - What’s a person to do when they’ve eliminated all the big allergens—gluten, dairy, eggs, nuts—and they’re still having mysterious symptoms that seem to be aggravated by their diet? Maybe you...

6 Older Studies That Got No Love but Should Have

March 06 2018 - "Back in my day, science came harder. We may not have had your fancy longitudinal data analyzing software, your iterated pool of available data upon which to build, or your worldwide network of instan...

How to Establish a Healthy Gut in Your Primal Baby

May 07 2014 - Yes, folks: it's another post about the gut. But today's advice is geared toward all the Primal babies out there in preconception, in utero, and in diapers. Because for the first few years, they're p...

Coca-Cola Cares About Your Health

November 04 2009 - It’s the stuff of quintessential irony. Paradox. An absurdity so egregious it’s painful to type, let alone view on the screen. (There’s actual smoke rising from my keyboard….) We’re talking ...

Will Eating Red Meat Kill You?

March 14 2012 - This is another special guest post from our favorite study-dismantler, Denise Minger. Read all of her previous Mark's Daily Apple articles here, here, here and here, pay her website a visit, and stay ...

Is Organic a Scam? – Biodiversity, Soil Health, Carbon Sequestration, Bee Activity, and Worker Health

October 16 2012 - At first glance, these may seem inconsequential to the casual reader. Biodiversity? That sounds like some fancy newspeak conjured up by Greenpeace! Soil health? How can soil be healthy? It's just a co...

New Findings: The Link Between Cancer and Exercise

December 06 2008 - Lance Armstrong has always been seen as the exception, rather than the rule. Conventional wisdom told us that he succeeded in spite of his cancer; that exercise is the realm of the healthy, rather tha...

15 Alternatives to Sitting Meditation

November 10 2015 - No longer the sole province of the hemp-swathed sprouting enthusiast, meditation's popularity has exploded across our collective faces. Tech companies have embraced mindfulness meditation as the ulti...

Dear Mark: Better Rest, and a Parent’s Nightmare: Tablets and Pickiness

January 29 2018 - For today's edition of Dear Mark, I'm answering two questions from readers. First, does "better rest" exist? I think it does, and I give the two "types" of rest I find to be the most effective. Second...

Dear Mark: Acrylamide, Sprint Alternatives, Gynoid Fat, and Adult Bed Sharing

January 21 2013 - In this week's edition of Dear Mark, I'll be covering three wide-ranging topics. First is acrylamide, the french fry toxin, the coffee carcinogen, the rat destroyer. It appears in almost every starchy...

15 Reasons Not to Trust That Latest Nutritional Study

April 06 2016 - Nutritional studies are often the best we've got. Without them, we'd be plucking anecdotes from a swirling vortex of hearsay, old wives' tales, and prejudices. Some actionable information would defini...

25 Ways to Improve Your Insulin Sensitivity

April 01 2015 - Insulin does a lot of important things for us. It pulls glucose from the blood and fritters it away into our cells to be burned for energy or stored as glycogen. It prevents hyperglycemic toxicity to...

Art and Mark on Doping, Endurance and Health

June 02 2007 - A few months back I exchanged a series of interesting letters with Art De Vany on fitness, doping, cardiovascular health and other issues related to health and to endurance athletes in particular. Her...

The A-to-Z Guide to Leading a Primal Lifestyle

October 07 2015 - Print this out. Bookmark it. Send it to friends who don’t quite get the Primal thing. Consider this a valuable resource for all-things Primal. It’s a nice, alphabetical encapsulation of what it me...

Should We Allow Drugs in Sports?

July 28 2008 - Dear Mark, I know you used to be involved in triathlon sports administration. I see so much written about "banned substances" and "cheating" going on in the world of professional sports these days,...

10 Baby Steps to Help You “Get Primal”

August 07 2009 - For this month?s 30-day challenge, we realize that everyone is starting from a different place. As much as we learn from our hardcore Grokkers, we welcome Primal newcomers with open arms and eager ear...

15 Alternatives to Sitting Meditation

November 10 2015 - No longer the sole province of the hemp-swathed sprouting enthusiast, meditation's popularity has exploded across our collective faces. Tech companies have embraced mindfulness meditation as the ulti...

The Mysterious World of Smell

April 27 2011 - What can you smell around you right now? Food? Coffee? Copier ink? Soil? Cleaners or chemicals? An office mate’s cologne from twenty feet away? It’s true we apprehend the world primarily through p...

7 Childhood Activities that Can Make You Healthier and Happier

August 19 2015 - Both my kids are grown now, but I still enjoy thinking back on the days when they were little. I can still see them covered in sand while digging on the beach, waiting enthusiastically for the next wa...

Dairy Intolerance: What It Is and How to Determine If You Have It

December 24 2013 - I often say that "dairy is fine and even healthy if you tolerate it." But what exactly does that mean? How do you know if it's "not okay"? You could be reacting poorly to the lactose, the casein, the ...

Measuring Ketones: What, When, Why, and How

June 30 2020 - Keto is unique compared to other diets because there is an objective marker that tells you if you’re on the right track. With an easy at-home test, you can confirm that you are, in fact, in a state ...

How to Foster Healthy Body Image in Children

October 06 2020 - I belong to a ladies' trail running community online. These women are cool, badass humans who perform amazing feats with their bodies. Last month, someone asked the group if they ever struggle with bo...

Brain Benefits of Playing Instruments

December 02 2020 - One of my biggest inspirations was my late father, Laurence Sisson. He supported our family as a painter, primarily water color paintings of New England nature scenes. His work ethic was insane as was...

Learning Through Play: 101 Ways To Keep Young Minds Occupied At Home

March 31 2020 - Parents, right off the bat, let me say that there is no right way to be feeling about the current situation. Relief, anxiety, excitement, dread are all normal. We’re all figuring this out as we go a...

25 Ways to Improve Your Insulin Sensitivity

April 01 2015 - Insulin does a lot of important things for us. It pulls glucose from the blood and fritters it away into our cells to be burned for energy or stored as glycogen. It prevents hyperglycemic toxicity to...

12 Daily Habits for Primal Well-Being

September 11 2018 - Most longtime readers of this blog could probably rattle off a dozen daily habits based on the inviolable Primal Laws. That's not exciting, though. Let's consider the basics just that: basics you s...

Doctors as Middlemen?: Direct-to-Consumer Online Testing Services and Other Consumer Health Trends

January 18 2011 - An alarming new health trend has medical professionals scurrying around issuing dire warnings of impending doom and death. As a recent piece in the Wall Street Journal relays, consumers are taking the...

15 Alternatives to Sitting Meditation

November 10 2015 - No longer the sole province of the hemp-swathed sprouting enthusiast, meditation's popularity has exploded across our collective faces. Tech companies have embraced mindfulness meditation as the ulti...

How to Establish a Healthy Gut in Your Primal Baby

May 07 2014 - Yes, folks: it's another post about the gut. But today's advice is geared toward all the Primal babies out there in preconception, in utero, and in diapers. Because for the first few years, they're p...

Adaptogen Effects: American and Asian Ginseng

June 22 2017 - I’ve been using adaptogens for quite some time, but in the last year I've been experimenting a little more with them. You may have caught my mention of a few adaptogenic varieties in one version o...

Top 10 True Old Wives’ Tales

February 12 2008 - - We spent last Tuesday explaining why the top 10 health myths were...well...myths. Today we present you the top 10 health-based old wives' tales that actually are true. (more…)

7 Childhood Activities that Can Make You Healthier and Happier

August 19 2015 - Both my kids are grown now, but I still enjoy thinking back on the days when they were little. I can still see them covered in sand while digging on the beach, waiting enthusiastically for the next wa...

Dear Mark: Better Rest, and a Parent’s Nightmare: Tablets and Pickiness

January 29 2018 - For today's edition of Dear Mark, I'm answering two questions from readers. First, does "better rest" exist? I think it does, and I give the two "types" of rest I find to be the most effective. Second...

10 Alternative Therapies for ADD & ADHD

December 27 2017 - A few months back, I put together an article on alternative therapies for depression. Many readers  showed a lot of interest in some of the emerging non-drug treatments in that field, and, more impor...

How to Foster Healthy Body Image in Children

October 06 2020 - I belong to a ladies' trail running community online. These women are cool, badass humans who perform amazing feats with their bodies. Last month, someone asked the group if they ever struggle with bo...

Brain Benefits of Playing Instruments

December 02 2020 - One of my biggest inspirations was my late father, Laurence Sisson. He supported our family as a painter, primarily water color paintings of New England nature scenes. His work ethic was insane as was...

Heritage Turkey and Mashed Parsnips

November 10 2019 - Thanksgiving is only a couple weeks away and in the United States this means one thing: turkey. Few other foods seem to dominate a holiday like this bird with a mind-boggling demand of 45+ million tur...

I Am Finally on the Right Path to Optimum Health and Happiness

February 22 2013 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

I Thought I Was Cursed to Live a Sort of Half Life

June 30 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

From Bedridden to Radiance: How I Used a Holistic Lifestyle to Heal From a Near-Death Accident

October 19 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

3 More Primal Blueprint Tales of Transformation

November 12 2010 - It's time for another healthy dose of inspiration from Mark's Daily Apple readers that took control of their health and turned their lives around. Many thanks to Jason, Marti and Dan for sharing their...

The Way I Used to Live Life Was Slowly Destroying Me

December 19 2014 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

Finding Balance After A Lifelong Eating Disorder

August 25 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

My Transformation Was Bigger Than Me

September 20 2013 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

The More You Seek, The More You Find

November 17 2017 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

Jimmy Moore: Livin’ La Vida Low-Carb & Lovin’ It

March 13 2007 - Apples: I'm very pleased to bring you a can't-miss interview with everyone's favorite low-carb blogger, low-carb rock star Jimmy Moore of Livin' La Vida Low-Carb. Jimmy's wildly popular blog (and new ...

Dear Mark: Acrylamide, Sprint Alternatives, Gynoid Fat, and Adult Bed Sharing

January 21 2013 - In this week's edition of Dear Mark, I'll be covering three wide-ranging topics. First is acrylamide, the french fry toxin, the coffee carcinogen, the rat destroyer. It appears in almost every starchy...

15 Reasons Not to Trust That Latest Nutritional Study

April 06 2016 - Nutritional studies are often the best we've got. Without them, we'd be plucking anecdotes from a swirling vortex of hearsay, old wives' tales, and prejudices. Some actionable information would defini...

25 Ways to Improve Your Insulin Sensitivity

April 01 2015 - Insulin does a lot of important things for us. It pulls glucose from the blood and fritters it away into our cells to be burned for energy or stored as glycogen. It prevents hyperglycemic toxicity to...

Can Exposure to Non-Primal Foods Actually Help?

March 15 2016 - Are we shortchanging ourselves by complete elimination of potentially allergenic or sensitizing foods like wheat, peanuts, or dairy? Do we become even more sensitive to "bad" foods by avoiding them e...

Reader Response: Fast Food Indulgence, Dirty Marketing Tricks and Personal Responsibility

March 06 2008 - In response to last month's post about Carl Jr.’s fat fetish, conversation got going about occasional fast food indulgence (the temptations, the how-to’s, etc.) as well as whether we were placing ...

Dear Mark: Exercise and Gut Diversity; Pregnancy and Calories

June 16 2014 - For today's edition of Dear Mark, we've got a two-parter. First up is a discussion of the latest (and only) exercise and gut flora study. It's been making the rounds and even I gave it a brief mention...

The Not So Definitive Guide to Diet Soda

January 26 2011 - Before I begin, I want to make something clear: this is not your standard definitive guide to whatever. I'd like to be able to issue a proclamation regarding diet soda that stands the test of time imm...

What We Get Wrong About Childhood Obesity

November 20 2019 - Weight Watchers (recently rebranded to WW) put out an app for kids and teens who want to lose weight a few months ago. It's called Kurbo, and it assigns "traffic light" color codes to different foods....

How to Recover from Holiday Overindulgence

November 30 2020 - So, you overdid it...or just ate something that doesn't work with your body. Maybe you didn’t binge per se but you abandoned the original plan and now you're feeling the pain. You ate, maybe more th...

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