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A Beginner’s Guide to Reading Scientific Research

December 05 2019 - Scientific journal articles can be incredibly intimidating to read, even for other scientists. Heck, I have a Ph.D. in a research science and have authored scientific papers, but sometimes I look at a...

Research Suggests Exercise Motivation Associated with Body Weight

January 31 2008 - New research conducted by researchers at Mount Allison University in New Brunswick, Canada suggests that thinner people are more motivated to exercise than their heavier peers. In a study initially...

Is the Paleo Diet Supported by Scientific Research?

July 01 2015 - People constantly demand proof for the efficacy of the Primal eating plan. And I'm glad they do. The Primal Blueprint makes sense on an intuitive level, and those success stories we see every Friday ...

Dear Mark: Latest in Gene Expression Research

May 24 2010 - One of my favorite topics, as many of you know, is epigenetics. It’s the burgeoning area of science that has blown apart the traditional nature-nurture dichotomy by examining the lifestyle-induced a...

Omega-3 for Health: What the Latest Research Shows

August 02 2018 - It's been a long time since I published the Definitive Guide to Fish Oils. Oh sure, here and there I've cited some research supporting the beneficial effects of fish fat, but it almost goes without...

Is the Paleo Diet Supported by Scientific Research? – Part 2

July 07 2015 - Last week, I countered claims that "paleo gots no science" with summaries of five recent (and not so recent) papers supporting the paleo/Primal approach to diet. The reception to that post was strong...

The Best of 2017: Research Insights and Other Breakthroughs

December 20 2017 - Each year is fuller than the last. More and more scientific papers are published each year, and that trend is only quickening. The same trend goes for books, products, businesses. Humans are incredibl...

7 Mistakes to Avoid When You’re Reading Research

December 17 2019 - A couple weeks ago I wrote a post about how to read scientific research papers. That covered what to do. Today I’m going to tell you what NOT to do as a consumer of research studies. The followin...

Metabolism and Menopause: What Does Research Suggest Is the Best Dietary Strategy?

August 01 2018 - After my recent post on keto for women, I got a lot of feedback. One of the most common themes: "But what about menopause?" I heard from dozens of women in both the comment section and in emails who w...

Gender Bias in Medical Research: How It Operates and Why It Matters

October 17 2017 - Some months ago the issue of gender bias in medical research came up on the comment board. It was certainly an issue I'd occasionally read about. But I'm also a proponent of lifestyle design and inter...

Is the Paleo Diet Supported by Scientific Research?

July 01 2015 - People constantly demand proof for the efficacy of the Primal eating plan. And I'm glad they do. The Primal Blueprint makes sense on an intuitive level, and those success stories we see every Friday ...

Dear Mark: Latest in Gene Expression Research

May 24 2010 - One of my favorite topics, as many of you know, is epigenetics. It’s the burgeoning area of science that has blown apart the traditional nature-nurture dichotomy by examining the lifestyle-induced a...

Omega-3 for Health: What the Latest Research Shows

August 02 2018 - It's been a long time since I published the Definitive Guide to Fish Oils. Oh sure, here and there I've cited some research supporting the beneficial effects of fish fat, but it almost goes without...

Is the Paleo Diet Supported by Scientific Research? – Part 2

July 07 2015 - Last week, I countered claims that "paleo gots no science" with summaries of five recent (and not so recent) papers supporting the paleo/Primal approach to diet. The reception to that post was strong...

7 Mistakes to Avoid When You’re Reading Research

December 17 2019 - A couple weeks ago I wrote a post about how to read scientific research papers. That covered what to do. Today I’m going to tell you what NOT to do as a consumer of research studies. The followin...

Metabolism and Menopause: What Does Research Suggest Is the Best Dietary Strategy?

August 01 2018 - After my recent post on keto for women, I got a lot of feedback. One of the most common themes: "But what about menopause?" I heard from dozens of women in both the comment section and in emails who w...

Weighing the Evidence: Science and Anecdote in Nutrition Studies

September 14 2009 - I was a science major (biology) in college, yet I have always been a little suspicious of the use of the “scientific method” when it comes to biological systems – especially humans. I guess it s...

Do Artificial Sweeteners Cause an Insulin Spike?

February 03 2011 - The notion that artificial sweeteners (and sweet tastes in general) might produce an insulin response is one of those murky memes that winds itself around the blogs, but it's never stated one way or t...

Homeopathy is (Mostly) Hogwash

January 25 2011 - On the docket today: a meaty, slippery, jam-packed can of worms. Makes you just lick your lips in anticipation, doesn’t it? Last week’s direct to consumer health testing post got this one going. I...

What’s Up With Your Gut? – Beneficial Bacteria and Good Digestive Health

April 20 2010 - Everyone knows (well, not everyone, but anyone who’s probably reading this) how crucial the early days of an infant’s life are for establishing good habits and healthy patterns for the rest of its...

Research Suggests Exercise Motivation Associated with Body Weight

January 31 2008 - New research conducted by researchers at Mount Allison University in New Brunswick, Canada suggests that thinner people are more motivated to exercise than their heavier peers. In a study initially...

Is the Paleo Diet Supported by Scientific Research? – Part 2

July 07 2015 - Last week, I countered claims that "paleo gots no science" with summaries of five recent (and not so recent) papers supporting the paleo/Primal approach to diet. The reception to that post was strong...

High Fat and Healthy: The Maasai Keep on Walking

July 21 2008 - Reader Peter emailed this new study today after he saw a discussion in which I was participating on Rusty's site (fitnessblackbook.com) regarding the Maasai diet. Investigators in this new study su...

Dear Mark: Leg Fatigue, Too Much Muscle Meat, Starch Persorption, and Hadza Study Author Responds

April 28 2014 - For today's edition of Dear Mark, we've got four questions. First is a question from a reader who exemplifies the "between a rock and a hard place" situation inherent to chronic cardio. Second, I addr...

Lessons Learned from Life in Space

March 02 2011 - They’re among the most studied individuals on the planet, so unique in their circumstances that an exclusive branch of medicine has been devoted to them, indeed a new subcategory of physiology itsel...

The Evidence Continues to Mount Against Chronic Cardio

July 09 2013 - It's been awhile since I did a post on chronic cardio. I had a good string of them going several years ago, and I thought I'd done a good job explaining why I was so opposed to excessive endurance tra...

The Fit Brain

August 20 2010 - You love the runner’s high, chiseled physique, steady energy, knock-out sleep, and that alluring post-workout glow. And, sure, there’s always the extraordinary cardiovascular benefit, cancer deter...

Do Foam Rollers Really Work?

April 19 2016 - I own a foam roller. Every fitness facility I've visited in the last three years has hosted a large arsenal of foam rollers, lacrosse balls, and other instruments of fascial torture. The CrossFitter ...

15 Reasons Not to Trust That Latest Nutritional Study

April 06 2016 - Nutritional studies are often the best we've got. Without them, we'd be plucking anecdotes from a swirling vortex of hearsay, old wives' tales, and prejudices. Some actionable information would defini...

Workout in a Pill?

August 30 2008 - As you probably already know, we here at MDA are all about making informed decisions that produce the best results with a minimal amount of effort. For example, what's the point in running yourself to...

A Beginner’s Guide to Reading Scientific Research

December 05 2019 - Scientific journal articles can be incredibly intimidating to read, even for other scientists. Heck, I have a Ph.D. in a research science and have authored scientific papers, but sometimes I look at a...

7 Mistakes to Avoid When You’re Reading Research

December 17 2019 - A couple weeks ago I wrote a post about how to read scientific research papers. That covered what to do. Today I’m going to tell you what NOT to do as a consumer of research studies. The followin...

Gender Bias in Medical Research: How It Operates and Why It Matters

October 17 2017 - Some months ago the issue of gender bias in medical research came up on the comment board. It was certainly an issue I'd occasionally read about. But I'm also a proponent of lifestyle design and inter...

The Health Paradox Paradox

May 31 2016 - A paradox is an observation that contradicts a previously-held assumption about reality. But assuming the observation is true, a paradox isn't really a paradox. It's not the new observation that's wro...

The Power of an Enriched Environment

July 23 2010 - In my leptin series a few weeks ago, I hashed out how dietary choices direct leptin levels – as well as leptin sensitivity and leptin resistance. But there’s more to leptin processing than just th...

How Simplifying Your Life Can Help You Refocus on What’s Important

March 14 2013 - Earlier this week I ran across a study that demonstrated a “simple lifestyle” can decrease our contact with toxic endocrine disrupting chemicals. The researchers looked at lifestyle elements like ...

IE: The Power of Intermittent Euphoria

August 23 2012 - A couple of weeks ago I wrote about slow living, the philosophy that encourages us to reclaim our time and consciously approach the way we live. Slow living isn’t as much about pace as it is depth o...

Benefits of Benevolence

December 09 2009 - It’s a message fitting for the season and one that gives a whole new meaning to the adage, to give is to receive. Acts of generosity, research shows, don’t just lead to emotional satisfaction; the...

Nature Tops Nurture? Scientists Wrong Again…

February 08 2008 - They just don't get it. Maybe they never will. Reader Karen was outraged enough to send us a link to a news story on MSNBC that states "Nature tops nurture for heavy kids, study says. Research on t...

Are Infrared Saunas Beneficial?

March 14 2017 - Last month, I installed an infrared sauna in my house. A company offered it to me to try out, and I was willing to give it a go, knowing a little about them already. It also inspired me to dig into t...

Dear Mark: Latest in Gene Expression Research

May 24 2010 - One of my favorite topics, as many of you know, is epigenetics. It’s the burgeoning area of science that has blown apart the traditional nature-nurture dichotomy by examining the lifestyle-induced a...

Is the Paleo Diet Supported by Scientific Research? – Part 2

July 07 2015 - Last week, I countered claims that "paleo gots no science" with summaries of five recent (and not so recent) papers supporting the paleo/Primal approach to diet. The reception to that post was strong...

Holy Cow! – Lessons in Food Respect

December 08 2010 - I love a good cow. Its meat is tasty, filling, and, especially when grass-fed and finished, full of fat-soluble vitamins, protein, and healthy fat. A cow’s organs are highly nutritious and affordabl...

Medical T.V. Is Bad For Your Health

October 15 2010 - Despite our culture’s “problematic” relationship with personal health (yes, I’m straining to be this diplomatic), we sure do like our medical T.V. There’s the news of course, the doctor talk...

Dear Mark: What Are the Health Benefits of Negative Ions?

August 20 2012 - Anyone who's been through a health store has heard about ions. If it's not someone offering samples of ionized water, it's someone selling ionized bracelets. It sounds wacky, woo-woo, crazy, and as if...

The Power of an Enriched Environment

July 23 2010 - In my leptin series a few weeks ago, I hashed out how dietary choices direct leptin levels – as well as leptin sensitivity and leptin resistance. But there’s more to leptin processing than just th...

CDC Report Suggests Americans Get Too Little Sleep

March 04 2008 - A study released Thursday by the U.S. Centers for Disease Control and Prevention (CDC) suggests that Americans are carving out too little time for sleep. Published in the agency’s Morbidity and M...

Cell Phone Health Hazard?

December 08 2009 - It’s become one of those oft-repeated half-truths floating around that people either assume to be unerringly true or completely false. It draws both sides of the spectrum: those that eschew all trad...

Are Humans Hard Wired For A Limited Social Circle?

March 09 2010 - Despite growing insight into neuroscience and the physical limitations of our consciousness, we have the tendency to ascribe a limitlessness to our minds. We readily accept the existence of certain bo...

What is Inflammation?

January 05 2012 - Inflammation is one of those words that people use without really thinking about its actual meaning. So today we're going to take a bit of a break from the blood lipid series to cover inflammation. In...

Chia Flax Hot Pudding

July 25 2015 - This is a guest post by Kelly LeVeque. Kelly is a certified holistic nutritionist, wellness expert and celebrity health coach based in Los Angeles, California. Be Well grew out of Kelly's lifelong pas...

Primal and Keto Collagen Recipes

February 25 2020 - Mark’s said it before: He advocates for collagen to become the fourth macronutrient. Collagen supports collagen-based structures in the body, such as fascia, ligaments, tendons, cartilage, skin, nai...

Caviar Served Three Ways (plus a Primal Blini Recipe)

December 29 2010 - Even if you’ve tried to keep your head buried in the sand and avoid the media headlines this year, the onslaught of bad economic news has been hard to ignore. Unemployment, defaulted mortgages, a ta...

Getting Canned: Is Canned Soup Really that Bad for You?

March 05 2008 - Although we’re slowly edging into spring, there’s still enough cold days left on the calendar that are sure to find you reaching for a can of soup. I mean honestly, could a meal be any easier? Sim...

7 Healthy Coffee Ideas for Every Primal Taste

August 09 2017 - Normally, I'm deep in the thick of nutritional research or other heady topics midweek. Today, not so much. I have coffee on the brain after trying a few new concoctions recently. As I've noted in the ...

Primal Egg Coffee: The Best Part of Waking Up?

July 24 2013 - Bulletproof coffee has taken the paleo world by storm. Not me, though. Don't get me wrong. I'm all for people dropping grass-fed butter and coconut/MCT oil into their high-quality coffee, blending ...

I Found My Health—and My Purpose In Life

May 25 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

A Few Simple Lifestyle and Diet Changes Have Transformed my Health

February 24 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

Success Story Follow-Up: Finding My Passion Through Healing

April 08 2019 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

Is Intermittent Fasting Bad for People with Thyroid Issues?

March 04 2020 - Is intermittent fasting a good idea for people with thyroid issues? It's a common question. After all, we know that the thyroid gland is a sensitive barometer of overall caloric sufficiency in the ...

From Bedridden to Radiance: How I Used a Holistic Lifestyle to Heal From a Near-Death Accident

October 19 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

Keto Was a New Way Of Life

March 04 2019 - It's Monday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

Success Story: Traveling the Cancer Journey

May 25 2020 - If you have your own success story and would like to share it with me and the Mark’s Daily Apple community please contact me here. I’ll continue to publish these as long as they keep coming in. Th...

My Energy Is Back, My Brain Isn’t Foggy, and All of My Health Markers Have Improved

July 14 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

Is the Paleo Diet Supported by Scientific Research?

July 01 2015 - People constantly demand proof for the efficacy of the Primal eating plan. And I'm glad they do. The Primal Blueprint makes sense on an intuitive level, and those success stories we see every Friday ...

Research Suggests Exercise Motivation Associated with Body Weight

January 31 2008 - New research conducted by researchers at Mount Allison University in New Brunswick, Canada suggests that thinner people are more motivated to exercise than their heavier peers. In a study initially...

Do Artificial Sweeteners Cause an Insulin Spike?

February 03 2011 - The notion that artificial sweeteners (and sweet tastes in general) might produce an insulin response is one of those murky memes that winds itself around the blogs, but it's never stated one way or t...

The Many Faces of the Sugar Monster

October 25 2008 - Our major qualm with high fructose corn syrup is its overwhelming ubiquity in processed food - which accounts for a significant portion of the average American's daily diet. While we may not fall prey...

Is Central Heating Related to Obesity?

January 31 2011 - Why are so many people in first-world countries so overweight? Why is metabolic syndrome so prevalent? The familiar contenders are diet and exercise - more specifically, the wrong kind of each. Both C...

Dear Mark: Feast or Famine Diet?

December 07 2009 - Among the questions I get from MDA readers are those that ask about timely diet trends – you know, the latest regimens highlighted in the media or promoted by high profile stars and athletes. Some a...

8 Reasons Why Low-Carb Diets Actually Work

December 23 2015 - The popular story of how low-carb diets work goes something like this: Reducing your carbohydrate intake lowers your insulin levels. Since insulin keeps fat locked into adipose tissue, lowering ins...

1 Meal vs. 3 Meals

March 14 2008 - Two collaborative studies (1,2) from the Agricultural Research Service and the National Institute on Aging offer a look at the physiological effects of 3 meals versus 1 meal a day in two crossover gro...

Do Low-Carb Diets Cause Insulin Resistance?

April 28 2015 - A few weeks back in the "How to Improve Your Insulin Sensitivity" post, I apparently dropped a bit of a bombshell: that very low carb diets can induce insulin resistance. Many of you wrote to me askin...

Save a Few Bucks, Gain a Few Pounds

June 15 2008 - The stories are everywhere on news broadcasts, mornings shows, and magazines. Bulk shopping, particularly as it’s defined by stock images of Sam’s Club and Costco, is the key to the current econom...

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