Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

Tell Me More
Stay Connected

Search Results

You Searched for liver

Dear Mark: Saturated Fat More Harmful to Liver Than Sugar?

June 04 2018 - For today's Dear Mark, I'm answering just one question from a reader. What are we to make of the new study purporting to show that saturated fat is the most harmful substance a liver can encounter? Sh...

Dear Mark: Folate Retention in Beans, Seeds, and Greens, Blended Liver Folate, No Vegetable/Fruit Full Study

March 26 2018 - For today's edition of Dear Mark, I'm answering three questions. You guys had more questions about folate. Since it's such an important vitamin, I answer those first. Then I discuss the study mentione...

Dear Mark: Vitamin B and Lung Cancer, Folate Stability in Liver, and Less DNA Damage on No Produce

March 19 2018 - For today's edition of Dear Mark, I'm answering three questions from readers. First, what do I make of the recent study showing a link between lung cancer in men and supplementation with vitamin B6 an...

Grilled Chicken Livers with Herb Butter

September 16 2017 - Liver is one of the most nutrient dense foods on the planet. A little bit is all you need to get a healthy dose of the vitamin A, copper, folate and zinc that liver offers. So, serving liver as an app...

Dear Mark: Erythritol and Weight Gain, Chicken Liver and Arsenic, and Tips for Laptops in the Sun

May 15 2017 - For today's edition of Dear Mark, I'm answering three questions from readers. First, is erythritol, one of the more common sugar alcohols, linked to weight gain? According to a new study, it is. What ...

Dear Mark: Superfoods, Plants for Pollution, Raw Liver Danger, and Irradiated ‘tsticles

May 01 2017 - For today's edition of Dear Mark, I'm addressing four questions and comments from readers. First up, do I subscribe to the idea of superfoods? If so, what do I like? If no, what do I consider "super"?...

Dear Mark: Hiking and Body Composition, Hiding Liver, Unconventional Testosterone Boosters, Cooked/Cooled/Reheated Potatoes, and Sirtuins

April 24 2017 - For today's edition of Dear Mark, I'm answering five questions from readers. First up, why isn't hiking giving one reader the shifts in body comp they expected? Two, is there actually a way to mask th...

Dear Mark: Alcohol and LDL, Liverwurst, Coffee and Milk, Kid Snacks, and High Carb Questions

April 17 2017 - For today's edition of Dear Mark, I'm answering 14 questions. The first concerns the effect of alcohol intake on LDL. Does it increase it or lower it (or both)? Next, what's the best liverwurst to eat...

Dear Mark: Coffee Alternatives for Liver Health, Vitamin C, Gelatin vs Collagen, NAC, My Favorite Way to Cook Greens, and Potato Starch Breading

April 10 2017 - For today's edition of Dear Mark, I'm answering several questions. First, if a person can't have coffee but wants the benefits it provides to liver health, what else can they try? Next, what role does...

Chicken Liver Stir-Fry

October 01 2016 - Chicken liver cooks quickly, making liver an ideal, if rarely used, protein for stir-fries. In this stir-fry recipe, chicken liver is a main ingredient. The meaty flavor gives an otherwise light dish ...

Dear Mark: Saturated Fat More Harmful to Liver Than Sugar?

June 04 2018 - For today's Dear Mark, I'm answering just one question from a reader. What are we to make of the new study purporting to show that saturated fat is the most harmful substance a liver can encounter? Sh...

Dear Mark: Folate Retention in Beans, Seeds, and Greens, Blended Liver Folate, No Vegetable/Fruit Full Study

March 26 2018 - For today's edition of Dear Mark, I'm answering three questions. You guys had more questions about folate. Since it's such an important vitamin, I answer those first. Then I discuss the study mentione...

Dear Mark: Vitamin B and Lung Cancer, Folate Stability in Liver, and Less DNA Damage on No Produce

March 19 2018 - For today's edition of Dear Mark, I'm answering three questions from readers. First, what do I make of the recent study showing a link between lung cancer in men and supplementation with vitamin B6 an...

Dear Mark: Erythritol and Weight Gain, Chicken Liver and Arsenic, and Tips for Laptops in the Sun

May 15 2017 - For today's edition of Dear Mark, I'm answering three questions from readers. First, is erythritol, one of the more common sugar alcohols, linked to weight gain? According to a new study, it is. What ...

Dear Mark: Superfoods, Plants for Pollution, Raw Liver Danger, and Irradiated ‘tsticles

May 01 2017 - For today's edition of Dear Mark, I'm addressing four questions and comments from readers. First up, do I subscribe to the idea of superfoods? If so, what do I like? If no, what do I consider "super"?...

Dear Mark: Hiking and Body Composition, Hiding Liver, Unconventional Testosterone Boosters, Cooked/Cooled/Reheated Potatoes, and Sirtuins

April 24 2017 - For today's edition of Dear Mark, I'm answering five questions from readers. First up, why isn't hiking giving one reader the shifts in body comp they expected? Two, is there actually a way to mask th...

Dear Mark: Alcohol and LDL, Liverwurst, Coffee and Milk, Kid Snacks, and High Carb Questions

April 17 2017 - For today's edition of Dear Mark, I'm answering 14 questions. The first concerns the effect of alcohol intake on LDL. Does it increase it or lower it (or both)? Next, what's the best liverwurst to eat...

Dear Mark: Coffee Alternatives for Liver Health, Vitamin C, Gelatin vs Collagen, NAC, My Favorite Way to Cook Greens, and Potato Starch Breading

April 10 2017 - For today's edition of Dear Mark, I'm answering several questions. First, if a person can't have coffee but wants the benefits it provides to liver health, what else can they try? Next, what role does...

Liver, Lobster and Locusts: How Bizarre Foods Win Acceptance

February 26 2015 - Way back in 2008 I published an article titled Insects: Not Just for Breakfast Anymore, and periodically since then I've advocated for bugs as food. It makes sense on so many levels, so I was thrilled...

Dear Mark: Liver for Babies, Flax Seed, and MCTs with Fruit

April 07 2014 - For today's Dear Mark, I've got a three-parter. First I discuss the suitability and proper dosage of grass fed beef liver for babies and toddlers. It's definitely a good choice, but you do have to kee...

Dear Mark: Hiking and Body Composition, Hiding Liver, Unconventional Testosterone Boosters, Cooked/Cooled/Reheated Potatoes, and Sirtuins

April 24 2017 - For today's edition of Dear Mark, I'm answering five questions from readers. First up, why isn't hiking giving one reader the shifts in body comp they expected? Two, is there actually a way to mask th...

What Causes Slow Post-Workout Recovery—and What Can You Do About It?

July 18 2018 - One of the biggest mistakes I see among people who exercise is they forget this core truth: we get fitter not from training, but from recovering from training. This doesn't just occur in beginners eit...

11 (Non-Dietary) Actions That Enhance Insulin Sensitivity

May 17 2018 - Insulin does a lot of important things for us. It pulls glucose from the blood and fritters it away into our cells to be burned for energy or stored as glycogen. It prevents hyperglycemic toxicity to ...

5 Studies I’d Like to See

March 27 2018 - Imagine money is no object. Imagine you wield absolute control over the scientific community and can direct it to run whichever study you desire. If you can dream it up, they'll get the subjects, prod...

Can Keto Actually Work For Hard-Training Endurance or Power/Strength Athletes?

March 21 2018 - Keto is red hot these days, and it’s not going away anytime soon. Call it the latest dietary fad, but keep in mind a great insight Robb Wolf told Joe Rogan on his podcast: keto was “likely the de...

Primal Action Point: 5 Fitness Recovery Techniques

January 19 2018 - Fitness recovery isn't only about rest. Certain techniques offer faster, more effective recovery after endurance or high intensity training—a big plus for those who compete or follow more intensive ...

Do “Dominant” Neurotransmitters Impact Training? (and a Giveaway)

January 18 2018 - Last year I was talking with Brad Kearns and Dave Dolle when Dave said something really interesting: he was using neurotransmitter analysis to build personalized training programs for his athletes. ...

Top 10 Paleo Apps

November 09 2017 - "Apps aren't paleo, Sisson. Grok waited for days for aurochs to wander within spear-chucking range, not overnight for the release of the iPhone X." True. But this is the world we live in. These are th...

9 Factors That Influence Testosterone Levels

September 06 2017 - In the last several weeks testosterone has come up on a pretty regular basis. I've written about it before, of course, but there's something about the novel elements (e.g. solar irradiation for certa...

CrossFit Training: How Going Primal Will Enhance Recovery

August 10 2017 - Exercise is a major stressor. But it's a major acute stressor, rather than a chronic one. It hits us, then it's over, and we recover. When the next session rolls around, we're better/faster/stronger/...

Dear Mark: Women and Violence, Reducing Extra Wine, High Intensity Interval Resting, Phosphatidylserine and Mental Stress, Rethinking Stress

February 05 2018 - For today's edition of Dear Mark, I'm answering five questions from readers. First up, do my recommendations regarding violence and martial arts in last week's "wildness post" also apply to women? Sec...

14 Healthier Ways to Spend Black Friday

November 21 2017 - For most of my life, Thanksgiving was spared the overt commercialization of the other holidays. Christmas has the gifts, Halloween the candy and costumes, Valentine's the chocolates, roses, jewelry, a...

What I’ve Learned from Eating Abroad

October 05 2017 - I've been lucky enough to travel to interesting places. The trips I've taken in the last 10-15 years, during my "Primal period," have been the most meaningful, rewarding, and downright enjoyable beca...

9 Factors That Influence Testosterone Levels

September 06 2017 - In the last several weeks testosterone has come up on a pretty regular basis. I've written about it before, of course, but there's something about the novel elements (e.g. solar irradiation for certa...

Is Keto for Everyone? Cautions, Caveats, and Contraindications

June 21 2017 - In a few months, I'll be releasing a book extolling the virtues of a ketogenic diet. I'm currently several months into a ketogenic experiment, which is going well. I just wrote a Definitive Guide exp...

ACEs and Primal Health

June 08 2017 - It’s fair to say that I gravitate towards tangible, actionable subject matter when it comes to improving my own and others’ health. Things like nutrition, fitness, sleep, hormonal responses, and s...

Dear Mark: Too Much Serotonin and Broccoli Sprouts

June 05 2017 - For today's edition of Dear Mark, I'm answering two questions from readers. The first is more of a comment, but it brought up a few questions for me to address. Is "more serotonin" always a good thing...

Summer Reset: 30 Days, 30 Actions (Plus a 21-Day Staff Challenge AND Giveaway!)

May 31 2017 - At the onset of our annual 21-Day Challenge this past January, I offered up a post that proposed thinking small—"41 Primal Action Items and Individual Experiments for Success in 2017." The idea here...

The Empathy Effect: How Befriending Your Future Self Can Impact Your Health Today

March 28 2017 - You are not the person you were fifteen years ago. The cells that compose your tissues and deliver oxygen have been recycled many times over. Your face has changed. You move differently. You're probab...

Dear Mark: Alternative Therapies Follow-up

February 20 2017 - For today's edition of Dear Mark, I'm answering four questions from last week's "Alternative Therapies" comment board. I asked you for questions and comments about other potential therapies, and you a...

Dear Mark: Erythritol and Weight Gain, Chicken Liver and Arsenic, and Tips for Laptops in the Sun

May 15 2017 - For today's edition of Dear Mark, I'm answering three questions from readers. First, is erythritol, one of the more common sugar alcohols, linked to weight gain? According to a new study, it is. What ...

Dear Mark: Superfoods, Plants for Pollution, Raw Liver Danger, and Irradiated ‘tsticles

May 01 2017 - For today's edition of Dear Mark, I'm addressing four questions and comments from readers. First up, do I subscribe to the idea of superfoods? If so, what do I like? If no, what do I consider "super"?...

Dear Mark: Hiking and Body Composition, Hiding Liver, Unconventional Testosterone Boosters, Cooked/Cooled/Reheated Potatoes, and Sirtuins

April 24 2017 - For today's edition of Dear Mark, I'm answering five questions from readers. First up, why isn't hiking giving one reader the shifts in body comp they expected? Two, is there actually a way to mask th...

Dear Mark: Liver for Babies, Flax Seed, and MCTs with Fruit

April 07 2014 - For today's Dear Mark, I've got a three-parter. First I discuss the suitability and proper dosage of grass fed beef liver for babies and toddlers. It's definitely a good choice, but you do have to kee...

Dear Mark: First Trimester Frustration, Liver Dosage, and NY Times Barefoot Piece

October 29 2012 - Being pregnant is tough - or so I hear. You're tasked with creating a child, with actually building an entire human being bit by bit from scratch. You have to carry that child, even as it grows to sev...

Poor Sleep May Make You (and Your Liver) Fat

March 14 2011 - Ah, sleep. Nothing like a good dose of the stuff, right? Losing even a single wink of your usual forty (or an hour, as the case may be) is enough to throw off an entire day. But do you know who mig...

Think Fatty Liver Is an Alcoholic’s Problem? Think Again

September 21 2007 - Akay Flickr Photo (CC) The BBC reports that fatty liver (as presented in the journal Obesity) is a growing yet silent epidemic affecting adults and, increasingly, children. Between one-quarter and ...

The Pros & Cons of Hormone Replacement Therapy for Primal Women

September 05 2018 - A Primal woman's first reaction to the prospect of taking synthetic hormone replacements for menopause? Probably a healthy dose of skepticism. We in the ancestral health community, after all, tend to ...

What Can Heat Do For Your Health?

August 29 2018 - A few months ago, I explored the benefits and applications of cold therapy. Today, I'm going to talk about the benefits and applications of heat therapy—one of the most ubiquitous and ancestral ther...

What Causes Slow Post-Workout Recovery—and What Can You Do About It?

July 18 2018 - One of the biggest mistakes I see among people who exercise is they forget this core truth: we get fitter not from training, but from recovering from training. This doesn't just occur in beginners eit...

Grilled Chicken Livers with Herb Butter

September 16 2017 - Liver is one of the most nutrient dense foods on the planet. A little bit is all you need to get a healthy dose of the vitamin A, copper, folate and zinc that liver offers. So, serving liver as an app...

Chicken Liver Stir-Fry

October 01 2016 - Chicken liver cooks quickly, making liver an ideal, if rarely used, protein for stir-fries. In this stir-fry recipe, chicken liver is a main ingredient. The meaty flavor gives an otherwise light dish ...

Chicken Livers with Mushrooms and Herbs

August 15 2015 - Chicken livers are not, perhaps, the first thing your eyes are drawn to in the butcher’s case. Most people don’t salivate over a slippery mound of raw livers like they do over a thick steak. Howev...

Bangin’ Liver

May 02 2015 - This is a guest post from Mary Shenouda, Paleo Chef and Lifestyle Coach. Mary, here! You may know me as Mary, The Paleo Chef. Or perhaps you know me as the #EatPlayCrush Girl on Instagram. Or maybe...

Silky-Smooth Chicken Liver Pâté

May 19 2012 - If you’ve only ever had chicken livers fried with onions or chopped up with hardboiled eggs, then it’s time to experience liver in a more decadent way. Not that Grandma’s chopped liver doesn’t...

Pork, Beef and Liver Terrine

August 06 2011 - Leave it to the French to create a dish that tastes and looks incredibly gourmet even though it’s made from not much more than ground meat. Making pâté de terrine does not take extraordinary culin...

Crispy Liver Hash Brown Patties

July 24 2010 - When most people think of beef liver, the next thing that comes to mind is fried onions. While liver and onions is certainly an easy way to serve this particular type of offal, it’s definitely not t...

Cajun Blackened Chicken Livers with Lemon and Garlic

July 10 2010 - In recent years, nose to tail eating has been embraced by celebrity chefs and gourmands, but it’s hardly a new idea. Eating an entire animal, not just the prime cuts of meat, is seen by many as a wa...

Strawberry Spinach and Basil Salad

September 15 2018 - We couldn't think of a better salad to close out the summer season with than this. Simple, fresh, and sweet, it's a perfect accompaniment to an omelet breakfast or a grilled chicken dinner, but it'...

Bacon Pancakes

August 25 2018 - Bacon pancakes sound like a sinful breakfast treat, but these slightly sweet, mostly savory cakes require no repentance. Fluffy, moist and salty with just hint of sweetness, bacon pancakes can be serv...

It Felt Like a Rebirth Into Living

September 07 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

All Of That Struggle, and Such a Simple Solution

August 31 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

The Missing Piece To My Puzzle (Plus a Recipe—and a Giveaway)

July 20 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

The Entrepreneurial Spirit: Making an Impact As a Primal Health Coach

March 16 2018 - In a newsletter last week, I shared the impetus behind the creation of the Primal Health Coach Institute, the world’s first ancestral health coaching school, and teased you with the promise of mot...

The Inflammation and Pain Caused By AS Was Gone For Good

January 12 2018 - It's Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark's Da...

I Didn’t Get a Migraine That First Week. Or That Second Week. Or Ever Again.

July 07 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

I Didn’t Realize I’d Been Getting in Shape for the Fight of My Life

May 12 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

My “Almost” Success Story

March 31 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

This Really Is a Family Story

February 10 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

My Transformation Was So Miraculous I Went on to Coach 200 Others

January 13 2017 - It’s Friday, everyone! And that means another Primal Blueprint Real Life Story from a Mark's Daily Apple reader. If you have your own success story and would like to share it with me and the Mark’...

Poor Sleep May Make You (and Your Liver) Fat

March 14 2011 - Ah, sleep. Nothing like a good dose of the stuff, right? Losing even a single wink of your usual forty (or an hour, as the case may be) is enough to throw off an entire day. But do you know who mig...

The Definitive Guide to Metabolic Flexibility

September 12 2018 - Metabolic flexibility is the capacity to match fuel oxidation to fuel availability—or switch between burning carbs and burning fat. Someone with great metabolic flexibility can burn carbs when they ...

Dear Mark: Marine Fat Sources, Not Gaining/Losing, Keto Breastfeeding

July 16 2018 - For today's edition of Dear Mark, I'm answering three questions. First, what are some less expensive sources of marine fat high in omega-3s? Is canned salmon a good, safe, effective option? Second, a ...

Fasting versus Carb Restriction: Which Works Better for What Scenarios

June 13 2018 - Both fasting and carb-restriction appear to operate along similar physiological pathways. Both lower carbs. Both increase fat-adaptation. Both have the potential to get you into ketosis. Both lower in...

Is Constant Ketosis Necessary – Or Even Desirable?

September 28 2017 - Good morning, folks. With next week's The Keto Reset Diet release, I've got keto on the mind today—unsurprisingly. I've had a lot of questions lately on duration. As I've mentioned before, a good si...

What Is the Vagus Nerve? (and How Does It Impact Health, Mood and Performance?)

February 16 2017 - In recent years, I’ve regularly vouched for the gut as our long-abused secondary brain. Given what most of us grew up learning in school, it can feel like a mammoth shift. Science and philosophy hav...

Dear Mark: More of Your Challenge Questions Answered

January 23 2017 - For today's edition of Dear Mark, I'm answering 11 questions. I answer questions about nutrient deficiencies and tremors, breastfeeding on the 21-Day Primal Blueprint Challenge, cheating without appa...

Dear Mark: What Does High HDL Mean? and Is Exercise Good or Useless for Weight Loss?

December 26 2016 - Today's edition of Dear Mark is a relatively brief two-parter, but it's a good one. First, I answer a question about HDL. Is higher good? Is higher (sometimes) bad? How does a person make sense of all...

Dear Mark: IGF-1 and Fasting, Ex-CrossFitter Fitness Maintenance, and Barre Training

September 26 2016 - For today's edition of Dear Mark, I'm answering three questions from readers. First, what's the deal with IGF-1, growth hormone, and intermittent fasting? Some people say fasting increases growth horm...

How to Accept Your Body After Significant Weight Loss

September 15 2016 - There are many meaningful reasons people go Primal: they want to improve their fitness, increase their longevity, feel younger, reverse lifestyle conditions, heal hormonal imbalances, enhance fertilit...

Join Over 300,000 Subscribers!

Signup and get:

Primal Blueprint Fitness plus 7 other eBooks
7-Day Course on Primal Fundamentals
Special Offers and More!