Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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August 06, 2017

Weekend Link Love – Edition 463

By Mark Sisson

weekend_linklove in-lineRESEARCH OF THE WEEK

Reducing sugar intake may be the key to reducing health care costs.

In a mouse model of Alzheimer’s, capsaicin (spicy component of hot peppers) improves cognitive function and reduces synapse loss.

Neanderthal genetic introgression may have shaped the modern human brain.

There’s a big link between substance abuse and sleep loss in adolescents.

Lutein, found in spinach, eggs, kale, and avocado (among others), may counter aging’s effect on the brain.

A new technique promises to remove 99% of BPA from water in half an hour.

Humans have been manipulating forest ecologies for at least 45,000 years.

Even sedentary seniors benefit from HIIT.


Episode 180: Elle Russ and Brad Kearns, Part 1: Hosts Elle Russ and Brad Kearns chat about the long-awaited release of the Primal Endurance Online Mastery Course.

Each week, select Mark’s Daily Apple blog posts are prepared as Primal Blueprint Podcasts. Need to catch up on reading, but don’t have the time? Prefer to listen to articles while on the go? Check out the new blog post podcasts below, and subscribe to the Primal Blueprint Podcast here so you never miss an episode.


If we really want to compress morbidity and increase healthy longevity, we need to focus on the fundamentals of the aging process.

How Bret McClellan used the Primal Health Coach cert to launch and maintain a successful health coach business with his wife.


The war on salt is entirely misguided.

Soybean oil is officially heart-healthy!


A message to vegans from a vegan.

The existence of biology may be a fluke of physics, according to a new hypothesis.

What do our microbiomes say about us?

Psilocybin helps people reconnect with the world, not escape it.


How I know we’re doing good things: Elizabeth Resnick explains how the Primal Health Coach certification has ignited her passion, fueled her knowledge, and enhanced her business.

Sometimes I feel like we’re living in a Philip K. Dick novel: Professional cuddling on the rise.

I actually think this could reduce healthcare costs: DIY pharmaceuticals.

I tend to agree: A fast mile is more impressive (and realistic) than a slow marathon.

I need a new sponge: So do you, probably.



One year ago (Aug 6– Aug 12)


I’d like to hop in for a visit just to knock out a few chin ups on marks famous pergola.

– I smell a contest, tribal.

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11 Comments on "Weekend Link Love – Edition 463"


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15 days 5 hours ago

I’ve been taking a macular supplement that contains lutein, trans-zeaxanthin, and meso-zeaxanthin, glad to know it may be helping my brain and lord knows I need all the help with that organ I can get. 🙂

The state of our water supply is a huge concern, looks like we come up with one solution to remove BPA from our water supply, which is awesome, but now we have to come up with solutions to remove the replacements for BPA, a bit discouraging.

14 days 1 hour ago

I have retinitis pigmasosa and was wondering if that supplement helps?

13 days 15 hours ago

I also heard about a report that indicated that our water supply is also contains more and more estrogen, primarily due to the increased use of birth control tablets, which find their way into the water supply – I need to research the truth to this report. testosterone levels have halved for men in the last 20 years, and at this rate will will end up self-destructing.

Elizabeth Resnick
14 days 22 hours ago

First of all, thanks for the shoutout:) Couldn’t be more thrilled with the Primal Health Coach program…love everything about it! And the piece by Melody Schoenfeld (about vegans) was so right on. As a former vegetarian/vegan who now feels amazing living a primal lifestyle, I agree that we all need to get along! Oh and Mel Joulwan’s coleslaw recipe sounds great, but I am way too lazy to make my own mayo now that I can just order it from Primal Kitchen!

14 days 20 hours ago

Fundamentals of Aging… got to the profanity and stopped reading. Writers should not assume puking 8th grade profanity on people is just fine because it’s the internet. It’s uncivil and inconsiderate. If you’re mouth is in the gutter so is your brain. Not interested.

14 days 10 hours ago

It’s unfortunate you allowed your pearl-clutching to keep you from reading and considering some profound and interesting information. Especially considering the swear word was quoted from a poem by Robert Conquest, who himself was paraphrasing Shakespeare.

14 days 8 hours ago
“Robert Conquest, a historian of Soviet Russia and a poet, once summarized Shakespeare’s 28-line poem, The Seven Ages of Man,’ in five lines.” Gratuitous profanity is one thing but sometimes within context it can be used to make a point. The author of the article introduces us to Leonard Hayflick, a famous gerontologists who postulates that a tremendous amount of money and effort is spent on trying to correct the symptoms of disease and aging rather than identifying the source causes. You could contact Robert Conquest and let him know you were offended by his intended-to-be-humorous offering, but he died… Read more »
14 days 6 hours ago

In principle I agree with Tuba. Anyone who can’t keep from spewing profanity in order to make a point is seriously in need of expanding their vocabulary. I’m not interested in reading that sort of thing either. The article in question, however, was actually not that bad. I’ve seen much worse.

Gentleman Jak
14 days 7 hours ago

I was actually having a discussion with someone over Twitter the other day about running shorter distances versus 5k and higher. My general sentiment is similar to Mark’s. I would much rather have a fast 1 mile run as opposed to working on longer distances.

My reasons are two-fold. First, it’s easier on the joints. Second, if something is really going to chase me for over a mile, then I’ll just stand and fight. No point dying AND being exhausted.

Have Jerky Will Travel
Have Jerky Will Travel
14 days 5 hours ago

Re: Humans manipulating forest ecologies.

Not just in the tropics…also in the Sierra Nevada.

El marquisio
El marquisio
13 days 2 hours ago
Ok this is off topic but I wanted to say this somewhere, here are the things I dislike in Primal lifestyle: The barefoot thing is exaggerated (but I like to walk barefoot in the grass every once in a while to get this connection with the earth- isn’t called earthling or something like that?) The stand-up desk, no. I sit and I move regularly. The PB stance on this has evolved by the way. The low carb aspect: I eat bread and plenty of carbs every day (rice, potatoes, wheat flour based things) and I love it, low carb just… Read more »