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	<title>Comments on: Vytorin: Big Blow for Big Pharma</title>
	<atom:link href="http://www.marksdailyapple.com/vytorin/feed/" rel="self" type="application/rss+xml" />
	<link>http://www.marksdailyapple.com/vytorin/</link>
	<description>Serving up health and fitness insights (daily, of course) with a side of irreverence.</description>
	<pubDate>Sat, 06 Sep 2008 22:13:54 +0000</pubDate>
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		<title>By: Mark&#8217;s Daily Apple &#187; Blog Archive &#187; Where Have All the Studies Gone?</title>
		<link>http://www.marksdailyapple.com/vytorin/#comment-23937</link>
		<dc:creator>Mark&#8217;s Daily Apple &#187; Blog Archive &#187; Where Have All the Studies Gone?</dc:creator>
		<pubDate>Fri, 18 Jan 2008 20:20:23 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/vytorin/#comment-23937</guid>
		<description>[...] Vytorin: Big Blow for Big Pharma [...]</description>
		<content:encoded><![CDATA[<p>[...] Vytorin: Big Blow for Big Pharma [...]</p>
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		<title>By: Migraineur</title>
		<link>http://www.marksdailyapple.com/vytorin/#comment-23895</link>
		<dc:creator>Migraineur</dc:creator>
		<pubDate>Fri, 18 Jan 2008 16:32:35 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/vytorin/#comment-23895</guid>
		<description>Kevin - actually, the all-cause death rate is lowest among people whose cholesterol is between 180 and 220.  So your doctor is in error by isolating a single factor - heart health - and ignoring other health factors that Mark described in the main post, such as liver, muscle, and nervous system health, as well as cancer risk.

How much over 200 were you?</description>
		<content:encoded><![CDATA[<p>Kevin - actually, the all-cause death rate is lowest among people whose cholesterol is between 180 and 220.  So your doctor is in error by isolating a single factor - heart health - and ignoring other health factors that Mark described in the main post, such as liver, muscle, and nervous system health, as well as cancer risk.</p>
<p>How much over 200 were you?</p>
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		<title>By: Kevin Burnett</title>
		<link>http://www.marksdailyapple.com/vytorin/#comment-23761</link>
		<dc:creator>Kevin Burnett</dc:creator>
		<pubDate>Thu, 17 Jan 2008 20:41:07 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/vytorin/#comment-23761</guid>
		<description>Mark,

No worries, I'm tough.
So, that's the million dollar question - does having a lowered number actually do anything for me on an individual level.  My doctor was quite clear on the fact that he could not tell me that having a lower number would help me at all.  He says that accross a broad population it is pretty safe to say that lower numbers = better heart health, but in my case it may not make any difference.  That said, in his opinion, keeping the number down through the use of a statin was less risky (assuming I tolerate the drug well - I'm tested twice a year to make sure of this) than having it above 200.
So I may be taking it for nothing, but at this point it's a bet I'm willing to take.
Thanks for the great information.</description>
		<content:encoded><![CDATA[<p>Mark,</p>
<p>No worries, I&#8217;m tough.<br />
So, that&#8217;s the million dollar question - does having a lowered number actually do anything for me on an individual level.  My doctor was quite clear on the fact that he could not tell me that having a lower number would help me at all.  He says that accross a broad population it is pretty safe to say that lower numbers = better heart health, but in my case it may not make any difference.  That said, in his opinion, keeping the number down through the use of a statin was less risky (assuming I tolerate the drug well - I&#8217;m tested twice a year to make sure of this) than having it above 200.<br />
So I may be taking it for nothing, but at this point it&#8217;s a bet I&#8217;m willing to take.<br />
Thanks for the great information.</p>
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		<title>By: Mark Sisson</title>
		<link>http://www.marksdailyapple.com/vytorin/#comment-23734</link>
		<dc:creator>Mark Sisson</dc:creator>
		<pubDate>Thu, 17 Jan 2008 17:32:55 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/vytorin/#comment-23734</guid>
		<description>Kevin,

Warning: "tough love" ahead.

My whole point is that your cholesterol levels are irrelevant in the big health picture. I think you and your doctor have bought into the mistaken idea that low cholesterol is somehow better than high cholesterol and that any number totaling over 200 needs to be aggressively dealth with. It ain't necessarily so. I would suggest that if you were eating right and exercising appropriately, your body hit the exact numbers it needed and that's where it wanted to stay. There is no magic to having artifically low numbers (produced by taking statin drugs). And the side effects of the statins out weigh the possible benefits (those minor benefits are probably just a mild anti-inflammatory effect - not the lowered cholesterol). So in many regards, you CAN always do it with diet and exercise - if you pick the right ones.</description>
		<content:encoded><![CDATA[<p>Kevin,</p>
<p>Warning: &#8220;tough love&#8221; ahead.</p>
<p>My whole point is that your cholesterol levels are irrelevant in the big health picture. I think you and your doctor have bought into the mistaken idea that low cholesterol is somehow better than high cholesterol and that any number totaling over 200 needs to be aggressively dealth with. It ain&#8217;t necessarily so. I would suggest that if you were eating right and exercising appropriately, your body hit the exact numbers it needed and that&#8217;s where it wanted to stay. There is no magic to having artifically low numbers (produced by taking statin drugs). And the side effects of the statins out weigh the possible benefits (those minor benefits are probably just a mild anti-inflammatory effect - not the lowered cholesterol). So in many regards, you CAN always do it with diet and exercise - if you pick the right ones.</p>
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		<title>By: Kevin Burnett</title>
		<link>http://www.marksdailyapple.com/vytorin/#comment-23669</link>
		<dc:creator>Kevin Burnett</dc:creator>
		<pubDate>Thu, 17 Jan 2008 04:53:31 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/vytorin/#comment-23669</guid>
		<description>I'm of mixed feeling on this one.  Obviously these two drugs are suspect at best and the companies should be fined in a big way, but I do feel that cholesterol lowering drugs have their place.  In my case I was over 200 total cholesterol with a low HDL before I hit age 40.  I was working out 8 to 12 hours a week and eating very, very well (pretty much like you describe on this website) and yet my numbers were not good.
I ended up on a low dose statin and within 6 months I was down to a "healthy" number.
You cannot always do it with exercise and nutrition alone.</description>
		<content:encoded><![CDATA[<p>I&#8217;m of mixed feeling on this one.  Obviously these two drugs are suspect at best and the companies should be fined in a big way, but I do feel that cholesterol lowering drugs have their place.  In my case I was over 200 total cholesterol with a low HDL before I hit age 40.  I was working out 8 to 12 hours a week and eating very, very well (pretty much like you describe on this website) and yet my numbers were not good.<br />
I ended up on a low dose statin and within 6 months I was down to a &#8220;healthy&#8221; number.<br />
You cannot always do it with exercise and nutrition alone.</p>
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		<title>By: Aaron</title>
		<link>http://www.marksdailyapple.com/vytorin/#comment-23635</link>
		<dc:creator>Aaron</dc:creator>
		<pubDate>Wed, 16 Jan 2008 23:22:38 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/vytorin/#comment-23635</guid>
		<description>Follow the Flickr photo link towards the bottom of the post to shed a little light on the image.</description>
		<content:encoded><![CDATA[<p>Follow the Flickr photo link towards the bottom of the post to shed a little light on the image.</p>
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