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Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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January 24, 2007

The Buckler Brief

By Elliott

EVERYTHING YOU EVER WANTED TO KNOW ABOUT: DMAE, or dimethylaminoethanol (die-meth-ell-amino-eth-an-ell)

WHAT IT IS: DMAE is a precursor to acetylcholine, a neurotransmitter. DMAE is found naturally in fish, and you’ll find it in high-quality multivitamins as well.

WHAT IT DOES: Scientists believe that DMAE becomes methylated to choline inside the brain (this basically means it’s converted). Choline, a nutrient considered by the U.S. Government to be essential for human health, serves many important functions, most notably in the brain. In fact, it’s believed that a deficiency in choline is associated with dementia, Alzheimer’s disease and other types of mental debility. Drugs that help acetylcholine uptake are already widely used in Alzheimer’s studies. Hence, many scientists believe DMAE may support healthy brain function.

STUDIES SHOW: Studies show that DMAE can become methylated into choline. Scientists have already proven that DMAE converts to choline in the liver, making DMAE an important nutrient for liver health. Studies also have shown that DMAE may undergo a similar process in the brain, and it is believed that supplementing with DMAE serves a potentially vital role in brain health. DMAE has been shown to have what are known as “nootropic” effects. Nootropics are a class of drugs that have brain-boosting properties. (From the Greek noos, mind, and tropos, bend: mind-bending.) Studies of nootropics, including DMAE, show increased alertness, mental function, calm, and relaxation.

WHY WE LIKE IT: DMAE is a safe, gentle, non-drug nootropic. The potential benefits of DMAE include improved cognition, memory, mood, circulation, and alertness.
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