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	<title>Comments on: The Age of Antidepressants?</title>
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	<link>http://www.marksdailyapple.com/the-age-of-antidepressants/</link>
	<description>Serving up health and fitness insights (daily, of course) with a side of irreverence.</description>
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		<title>By: Lee</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-471128</link>
		<dc:creator>Lee</dc:creator>
		<pubDate>Tue, 03 Nov 2009 08:37:29 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-471128</guid>
		<description>It&#039;s all about money, the kick backs Dr&#039;s get for pushing one drug or another in an effort to boost Big Pharma&#039;s bottom line.</description>
		<content:encoded><![CDATA[<p>It&#8217;s all about money, the kick backs Dr&#8217;s get for pushing one drug or another in an effort to boost Big Pharma&#8217;s bottom line.</p>
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		<title>By: Diet and Depression &#124; How to Combat Depression with a Healthy Diet &#124; Mark's Daily Apple</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-466359</link>
		<dc:creator>Diet and Depression &#124; How to Combat Depression with a Healthy Diet &#124; Mark's Daily Apple</dc:creator>
		<pubDate>Mon, 19 Oct 2009 16:15:00 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-466359</guid>
		<description>[...] or replace their conventional treatments for depression. Since our post a few weeks ago on antidepressants, I’ve gotten a slew of emails asking me about the role of nutrition in mental health. In response [...]</description>
		<content:encoded><![CDATA[<p>[...] or replace their conventional treatments for depression. Since our post a few weeks ago on antidepressants, I’ve gotten a slew of emails asking me about the role of nutrition in mental health. In response [...]</p>
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		<title>By: Tue, Oct 6th &#8211; CrossFit Ireland - Great People. Great Fitness.</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-463216</link>
		<dc:creator>Tue, Oct 6th &#8211; CrossFit Ireland - Great People. Great Fitness.</dc:creator>
		<pubDate>Mon, 05 Oct 2009 23:02:38 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-463216</guid>
		<description>[...] Crystal Meth Lattes Are Bad For You - Mike Mahler The Age of Anti-Depressants? - Mark [...]</description>
		<content:encoded><![CDATA[<p>[...] Crystal Meth Lattes Are Bad For You &#8211; Mike Mahler The Age of Anti-Depressants? &#8211; Mark [...]</p>
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		<title>By: Brendon</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-459185</link>
		<dc:creator>Brendon</dc:creator>
		<pubDate>Wed, 16 Sep 2009 19:51:36 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-459185</guid>
		<description>Mark, I have read how white flour and sugar can lead to chromium depletion and how milk interferes with chromium absorption. Low levels of chromium, as you know, can be linked to depression. 

I have struggled, and continue to do so, with &quot;the blues&quot; and anxiety throughout the ups and downs of life. I truly believe that most cases of depression can be overcome with a clean &quot;paleo&quot; diet and plenty of vitamin D.

Thanks for all your great information!

Brendon</description>
		<content:encoded><![CDATA[<p>Mark, I have read how white flour and sugar can lead to chromium depletion and how milk interferes with chromium absorption. Low levels of chromium, as you know, can be linked to depression. </p>
<p>I have struggled, and continue to do so, with &#8220;the blues&#8221; and anxiety throughout the ups and downs of life. I truly believe that most cases of depression can be overcome with a clean &#8220;paleo&#8221; diet and plenty of vitamin D.</p>
<p>Thanks for all your great information!</p>
<p>Brendon</p>
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		<title>By: Trinkwasser</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-458589</link>
		<dc:creator>Trinkwasser</dc:creator>
		<pubDate>Mon, 14 Sep 2009 15:55:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-458589</guid>
		<description>Excellent point! Many cases of &quot;treatment resistant&quot; depression resolve when thyroid is adequately treated, and often thyroid *should* be treated at numbers many doctors regard as normal (like TSH 0f 3 or 5, or subclinically low T3 or T4)

There are somewhere around 50 - 100 chemicals which work as or modify the effects of neurotransmitters, and many of them respond to problems with the endocrine system via the hypothalamic-pituitary axis.

My &quot;depression&quot; is endemic to one side of the family and is more related to hibernation than suicidality. I&#039;ve been on and off various meds for years. Curiously (or not) discovering the blood glucose swinging from (mostly) nearly diabetic to nearly hypoglycemic several times a day and sitting on that has made a spectacular improvement to the depression and ADD, as has (probably) adding more Omega 3 and sat fats: maybe Vitamin D3 also.

IF this was placebo effect then how come different drugs have markedly different effects - and how come with a rational diet I am maintaining on 1/6 of my original dose? (I tried 1/12 of the dose but started slowing down again so it&#039;s not entirely driven by the high/low BG and hyperinsulinemia but controlling that has had major knock-on effects)

There are such a bunch of physical as well as mental stressors in modern life, including but not limited to crap diets and overexposure to environmental toxins, that finding the cause and dealing effectively with it may be hard. In many cases drugs are necessary but like statins they are used to medicate away the effects of an inappropriate diet/lifestyle instead of being limited to those who genuinely need them, or in the case of SSRIs for hypothyroid to cover up the actual cause of the problem</description>
		<content:encoded><![CDATA[<p>Excellent point! Many cases of &#8220;treatment resistant&#8221; depression resolve when thyroid is adequately treated, and often thyroid *should* be treated at numbers many doctors regard as normal (like TSH 0f 3 or 5, or subclinically low T3 or T4)</p>
<p>There are somewhere around 50 &#8211; 100 chemicals which work as or modify the effects of neurotransmitters, and many of them respond to problems with the endocrine system via the hypothalamic-pituitary axis.</p>
<p>My &#8220;depression&#8221; is endemic to one side of the family and is more related to hibernation than suicidality. I&#8217;ve been on and off various meds for years. Curiously (or not) discovering the blood glucose swinging from (mostly) nearly diabetic to nearly hypoglycemic several times a day and sitting on that has made a spectacular improvement to the depression and ADD, as has (probably) adding more Omega 3 and sat fats: maybe Vitamin D3 also.</p>
<p>IF this was placebo effect then how come different drugs have markedly different effects &#8211; and how come with a rational diet I am maintaining on 1/6 of my original dose? (I tried 1/12 of the dose but started slowing down again so it&#8217;s not entirely driven by the high/low BG and hyperinsulinemia but controlling that has had major knock-on effects)</p>
<p>There are such a bunch of physical as well as mental stressors in modern life, including but not limited to crap diets and overexposure to environmental toxins, that finding the cause and dealing effectively with it may be hard. In many cases drugs are necessary but like statins they are used to medicate away the effects of an inappropriate diet/lifestyle instead of being limited to those who genuinely need them, or in the case of SSRIs for hypothyroid to cover up the actual cause of the problem</p>
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		<title>By: PapaG44</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-458581</link>
		<dc:creator>PapaG44</dc:creator>
		<pubDate>Mon, 14 Sep 2009 14:46:43 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-458581</guid>
		<description>This is a great book that has helped me immensely.</description>
		<content:encoded><![CDATA[<p>This is a great book that has helped me immensely.</p>
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		<title>By: Mark Tyrrell</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-458534</link>
		<dc:creator>Mark Tyrrell</dc:creator>
		<pubDate>Mon, 14 Sep 2009 10:54:54 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-458534</guid>
		<description>The crazy thing is that antidepressants are little more effective than placebos in lifting the symptoms of depression about a third of people using placebos or antidepressants will notice some symptom reduction. 

Added to the fact that there has been a ten fold increase in the incidence of depression over the last fifty years (because we are living differently) 

There are basic emotional needs as well as the physical ones that Mark describes http://unk.com/t/3</description>
		<content:encoded><![CDATA[<p>The crazy thing is that antidepressants are little more effective than placebos in lifting the symptoms of depression about a third of people using placebos or antidepressants will notice some symptom reduction. </p>
<p>Added to the fact that there has been a ten fold increase in the incidence of depression over the last fifty years (because we are living differently) </p>
<p>There are basic emotional needs as well as the physical ones that Mark describes <a href="http://unk.com/t/3" rel="nofollow">http://unk.com/t/3</a></p>
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		<title>By: Anon</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-458473</link>
		<dc:creator>Anon</dc:creator>
		<pubDate>Mon, 14 Sep 2009 05:46:11 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-458473</guid>
		<description>I think this post handled the issue sensitively and I appreciate that. 

However, the complete Big Pharma bashing is uncalled for. Medicine--pharmaceuticals--saves peoples&#039; lives. My father&#039;s life expectancy has doubled because of the drugs that were created, tested, and distributed by so-called Big Pharma. What drugs? Chemotherapy drugs. Not to mention steroids, anti-nausea medications, vitamins, and pain killers that allow him to continue working full time despite having an extremely painful and aggressive form of cancer. 

Sure, there are problems in the system, but don&#039;t forget that real good is done for society by a lot of the people who work for these companies. Researchers spend their lives trying to make things better for the rest of us. The business side mishandles things, especially things that are human and not financial, but the industry as a whole is getting too much flack on here. 

I know the point of this post wasn&#039;t that all pharmaceuticals are bad. I just wanted to inject a reminder that the pharmaceutical industry is not black-and-white. Like most other things in life, it is extremely complex. But I willingly accept the flaws in order to receive the benefits. (Well, that&#039;s not entirely true, as I support a massive overhaul of the system, but for all intents, it&#039;s how it plays out in my real life.) 

One other thing, totally different from my initial point: GPs prescribing psychiatric medications can be dangerous. My partner has bipolar-1, and his GP put him on an SSRI. It nearly drove him into a manic episode. A psychiatrist would&#039;ve known better.</description>
		<content:encoded><![CDATA[<p>I think this post handled the issue sensitively and I appreciate that. </p>
<p>However, the complete Big Pharma bashing is uncalled for. Medicine&#8211;pharmaceuticals&#8211;saves peoples&#8217; lives. My father&#8217;s life expectancy has doubled because of the drugs that were created, tested, and distributed by so-called Big Pharma. What drugs? Chemotherapy drugs. Not to mention steroids, anti-nausea medications, vitamins, and pain killers that allow him to continue working full time despite having an extremely painful and aggressive form of cancer. </p>
<p>Sure, there are problems in the system, but don&#8217;t forget that real good is done for society by a lot of the people who work for these companies. Researchers spend their lives trying to make things better for the rest of us. The business side mishandles things, especially things that are human and not financial, but the industry as a whole is getting too much flack on here. </p>
<p>I know the point of this post wasn&#8217;t that all pharmaceuticals are bad. I just wanted to inject a reminder that the pharmaceutical industry is not black-and-white. Like most other things in life, it is extremely complex. But I willingly accept the flaws in order to receive the benefits. (Well, that&#8217;s not entirely true, as I support a massive overhaul of the system, but for all intents, it&#8217;s how it plays out in my real life.) </p>
<p>One other thing, totally different from my initial point: GPs prescribing psychiatric medications can be dangerous. My partner has bipolar-1, and his GP put him on an SSRI. It nearly drove him into a manic episode. A psychiatrist would&#8217;ve known better.</p>
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		<title>By: Jayadeep Purushothaman</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-458444</link>
		<dc:creator>Jayadeep Purushothaman</dc:creator>
		<pubDate>Mon, 14 Sep 2009 03:26:48 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-458444</guid>
		<description>I have been on the rough rides of several bouts of Bipolar depression myself and has some history in the family as well. I have seen or heard mostly of the other extreme - where people refuse to admit that there is a problem. So one reason you see more people on meds could be because people are consulting docs for their problems that they would never have admitted earlier.  

I have had a doc induce a manic and a subsequent depression(and a couple of deaths in the family during the time) because of overdoses of anti-depressants. I was on a supposedly life long medication, Lithium, which I have stopped since a while after getting my life in order - a regular exercise program, dumping all junk food and colas and choosing natural foods instead and walking away from two stressful jobs. Also my liver was impacted(but found early) due to side effects of some of the meds I was on. Right now, I guess I know the root causes of my problems and I think I have a handle on it. As many people point out here, it is the treating of the symptoms instead of the real causes the real problem here. But I believe this is a problem that can be treated without meds if the root cause is figured out and in my case nobody helped me find out for a long time till I figured it myself.</description>
		<content:encoded><![CDATA[<p>I have been on the rough rides of several bouts of Bipolar depression myself and has some history in the family as well. I have seen or heard mostly of the other extreme &#8211; where people refuse to admit that there is a problem. So one reason you see more people on meds could be because people are consulting docs for their problems that they would never have admitted earlier.  </p>
<p>I have had a doc induce a manic and a subsequent depression(and a couple of deaths in the family during the time) because of overdoses of anti-depressants. I was on a supposedly life long medication, Lithium, which I have stopped since a while after getting my life in order &#8211; a regular exercise program, dumping all junk food and colas and choosing natural foods instead and walking away from two stressful jobs. Also my liver was impacted(but found early) due to side effects of some of the meds I was on. Right now, I guess I know the root causes of my problems and I think I have a handle on it. As many people point out here, it is the treating of the symptoms instead of the real causes the real problem here. But I believe this is a problem that can be treated without meds if the root cause is figured out and in my case nobody helped me find out for a long time till I figured it myself.</p>
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		<title>By: Bonnie</title>
		<link>http://www.marksdailyapple.com/the-age-of-antidepressants/#comment-458336</link>
		<dc:creator>Bonnie</dc:creator>
		<pubDate>Sun, 13 Sep 2009 17:28:05 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=7977#comment-458336</guid>
		<description>I think you were able to articulate your issues very well in your post.   It is important that while certain things can help some people, only you know what&#039;s going on in your body.

As an acupuncturist I often deal with chronic conditions.  I think your ability to stand up for your body and your needs and remind people they haven&#039;t walked in your shoes is admirable and deserves some acknowledgement.  I wish many of my patient&#039;s could stand up and learn from what you just did.

While there is a lot of misuse and overuse of medications in today&#039;s world, there is a reason pharmaceuticals were manufactured in the first place.   They worked when nothing else did.    Additionally they often worked faster.

There is something to be said for living a life that is satisfying.  That in and of itself can help with your overall health.   We all need to make our OWN choices because owe are the only people who really know our bodies.   I think THAT is a lesson everyone needs to learn and remember.</description>
		<content:encoded><![CDATA[<p>I think you were able to articulate your issues very well in your post.   It is important that while certain things can help some people, only you know what&#8217;s going on in your body.</p>
<p>As an acupuncturist I often deal with chronic conditions.  I think your ability to stand up for your body and your needs and remind people they haven&#8217;t walked in your shoes is admirable and deserves some acknowledgement.  I wish many of my patient&#8217;s could stand up and learn from what you just did.</p>
<p>While there is a lot of misuse and overuse of medications in today&#8217;s world, there is a reason pharmaceuticals were manufactured in the first place.   They worked when nothing else did.    Additionally they often worked faster.</p>
<p>There is something to be said for living a life that is satisfying.  That in and of itself can help with your overall health.   We all need to make our OWN choices because owe are the only people who really know our bodies.   I think THAT is a lesson everyone needs to learn and remember.</p>
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