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Tell Me Something I Don’t Know

Posted By Mark Sisson On December 18, 2006 @ 8:11 pm In Big Pharma,Health,Women's Health | Comments Disabled

HRT is all over the news again. This, from Newsday [7]:

“Statistics from a major study revealing that rates of the most common form of breast cancer dropped dramatically between 2002 and 2003 are being greeted with applause and skepticism as the medical and advocacy communities digest the news.”

Yes, it’s a tough one to chew. In brief, cases of estrogen-receptor positive breast cancer (which accounts for nearly 3/4 of breast cancer cases) dropped dramatically from 2002 to 2003. This was the same time that several key studies, including a famous government-funded study (the Women’s Health Initiative [8]), found that hormone replacement therapy (or HRT), particularly that derived from mares – in drugs like Prempro and Premarin – was linked to a significant increase in breast cancer risk.

It makes sense. Estrogen is a powerful hormone and using it in drug therapy has been and continues to be a risky proposition. A dramatic drop in estrogen-receptor breast cancer cases, occurring in tandem with the much-publicized discontinued use of HRT by millions of women, isn’t something I think the drug industry or medical community ought to be stumped by. These are highly-trained, intelligent individuals, and frankly, I think the situation is quite clear. What’s to digest? In one year – the same year in which Prempro saw its sales cut by half – breast cancer rates dropped by over 7%; for women over age 50, the rate was 12%.

This is why it is so important to be critical of any drug therapy that is recommended to us, especially for treating health matters that are either part of aging or can be prevented or better addressed through lifestyle choices. Blood pressure pills and cholesterol-lowering pills and arthritis prescriptions can help, but as we see with the HRT scandal (and last year’s Vioxx and Celebrex disasters), there are always side effects. There are always unintended consequences.

This doesn’t mean you ought to toss your medications if there is a legitimate need for them; but arm yourself with knowledge, be ruthlessly critical of everything that anyone recommends to you, and consider whether there are safer, more natural alternatives. The alternatives are often not as easy in the short term, but they’re certainly easier than painful and even fatal side effects down the road.

Technorati Tags: HRT [9], hormone replacement therapy [10], estrogen [11], breast cancer [12], estrogen receptor positive [13], Premarin [14], Prempro [15], Newsday [16], drug side effects [17], pharmaceuticals [18]


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[7] Newsday: http://www.newsday.com/news/health/ny-hscanc1218,0,1769322.story?coll=ny-leadhealthnews-headlines

[8] Women’s Health Initiative: http://www.cwhn.ca/resources/menopause/hrt-glance.html

[9] HRT: http://technorati.com/tag/HRT

[10] hormone replacement therapy: http://technorati.com/tag/hormone+replacement+therapy

[11] estrogen: http://technorati.com/tag/estrogen

[12] breast cancer: http://technorati.com/tag/breast+cancer

[13] estrogen receptor positive: http://technorati.com/tag/estrogen+receptor+positive

[14] Premarin: http://technorati.com/tag/Premarin

[15] Prempro: http://technorati.com/tag/Prempro

[16] Newsday: http://technorati.com/tag/Newsday

[17] drug side effects: http://technorati.com/tag/drug+side+effects

[18] pharmaceuticals : http://technorati.com/tag/pharmaceuticals

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