Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

Tell Me More
Stay Connected

Tag: research analysis

Autism: A Brain or Whole-Body Disorder?

You could say this post is a long time coming. In the last few years, I’ve lost count of the huge number of emails I get from parents with kids who have special needs either asking for advice or explaining how The Primal Blueprint has made a significant difference for their children. These are parents who love their kids for all their abilities and differences and who want to explore every reasonable lifestyle intervention they can to make their kids’ lives everything they can and should be.

I’ll state the obvious here. I’m not a disability expert, but I’ve been moved and motivated by these parents’ emails. From a general health perspective, I’ve wondered how our modern lives could be contributing to the epidemic. Likewise, I’m curious how research can illuminate potential benefits of lifestyle interventions. What is the biological picture behind the dysfunction in these conditions, and how can biology be harnessed to restore functioning? A recent approach focused on the whole brain and whole body is asking those exact questions – and finding answers.

Read More

Is It Time to Retire the Low-Carb Diet “Fad”?

This is another special guest post from our favorite study-dismantler, Denise Minger. Read all of her previous Mark’s Daily Apple articles here, here, here, here and here, and pay her website a visit. Thanks, Denise, for clearing up the confusion once again!

Sweden is a land of many wonders – most of which put the USA to shame. They’ve got fjords, ABBA, and caviar in a tube. And while Americans get arrested for things like DUIs and stealing socks from Walmart, Swedes get arrested for the more admirable feat of smuggling butter.

Read More

Are Humans Hard-Wired to Be Optimistic?

If you ask most people, they’ll pretty much agree that optimism is better than pessimism. Oh, you might get one or two who laugh at the cockeyed optimists and their naivete about the world and its harsh, grim realities, but when you get down to it, optimists feel good about their lot in life, while pessimists feel bad about where they and the world are headed. Feeling good is a good, desirable state of being. Feeling bad about the future, well, just feels bad. Which would you rather experience?

Exactly.

Read More

Will Eating Red Meat Kill You?

This is another special guest post from our favorite study-dismantler, Denise Minger. Read all of her previous Mark’s Daily Apple articles here, here, here and here, pay her website a visit, and stay tuned for her upcoming book “Death by Food Pyramid” due out later this year.

We’re already 74 days into the new year, which can only mean one thing: it’s high time for our latest episode of Science Says Meat Will Kill You, complete with a brand new study and commercial-free viral media coverage! Have a seat and tune in (or at least set your DVR for later viewing).

If you haven’t had at least one family member, coworker, or soon-to-be-unfriended Facebook acquaintance send you this study as a reminder that you’re killing yourself, you’re either really lucky or your inbox is broken. Thanks to an observational study called Red Meat Consumption and Mortality freshly pressed in the Archives of Internal Medicine, a slew of bold headlines exploded across every conceivable media outlet this week:

Read More

The “Asian Paradox”: How Can Asians Eat So Much Rice and Not Gain Weight?

How the Primal community loves the concept of a dietary paradox. How we eagerly point to its various manifestations as supportive evidence for our way of eating, living, and moving. You know the French Paradox and how it confounds the experts. To mention all those smug surrender monkeys with their brie and their butter and their duck confit and their Gauloises and their seeming imperviousness to heart attacks is to make Dean Ornish binge on bran and pull out tuft after tuft of frizzy hair. And then there’s the lesser-known Israeli Paradox, which attempts to answer why Israelis have skyrocketing rates of heart disease despite a skyrocketing intake of “healthy” omega-6 fatty acids. In its wake, Walter Willet might be found weeping into a mug of safflower oil. There’s even an American Paradox – those who ate the most saturated fat had the least coronary heart disease – that had the minds of researchers thoroughly boggled.

Read More

Dear Mark: Fat Causes Brain Damage?

It feels good to get back to our regularly scheduled Monday morning programming. “Dear Mark” is a way for me to keep my finger on the pulse of the community, to respond quickly and directly to any issues that may arise. I try to keep abreast of all this stuff, but there’s a lot, and some will inevitably slip through the cracks. When that happens, you guys pick up the slack and keep me honest and informed. These Mondays give me a chance to respond to the things I would have otherwise missed or put off until another time. Thanks for that.

This past week, I received a massive influx of emails from readers worried about the results of a new study. I figured it was a good idea to address it. Here are a few of the messages:

Read More

What is Inflammation?

Inflammation is one of those words that people use without really thinking about its actual meaning. So today we’re going to take a bit of a break from the blood lipid series to cover inflammation. In later posts, I’ll dig deeper into how the inflammatory response works with stuff like exercise and heart disease, but for now, I’ll just get the basics out there.

Existence is suffering, according to certain schools of thought. I don’t know that I’d go quite that far, but I would emphatically state that anyone who spends a modicum of sentient time in the space time continuum we call existence is gonna experience some unpleasantness. A bump on the knee, a bacterial infection, an acute injury, a persistent illness, a death of a loved one, a broken heart. It’s a big and often angry world that doesn’t necessarily care about you, and something’s gotta give. When that happens and the sanctity of our bodies is interrupted by pain, injury, or illness, our bodies respond with inflammation.

Read More

How to Interpret Advanced Cholesterol Test Results

After last week’s post on interpreting traditional lipid tests, I promised a follow-up post on interpreting the advanced VAP and NMR Lipoprofile tests that provide measurements of particle size and all the various sub-fractions of HDL and LDL particles. I even hinted that it might be worth bypassing the traditional test entirely and going straight to the advanced stuff if you were going to get your cholesterol measured anyway, because of the greater accuracy and more detailed picture of your lipids the VAP and NMR tests provide.

Read More

How to Interpret Cholesterol Test Results

Before we get into the big job of interpreting cholesterol numbers, let’s review what cholesterol actually is.

Cholesterol is cholesterol: a waxy steroid of fat that serves as an essential structural component of cellular membranes and in the production of steroid hormones, vitamin D, and bile acids. Contrary to what the terminology indicates, there’s actually only one “type” of cholesterol in the human body, and it’s called, quite simply, cholesterol. What we think of when we use the word “cholesterol” is actually a lipoprotein – a fatty conglomerate of protein and lipids that delivers cholesterol and fat and fat-soluble nutrients to different parts of the body. It’s not just free cholesterol floating around in your blood; it’s cholesterol bound up by lipoproteins.

Read More

Does a High-Fat Diet Cause Type 2 Diabetes?

This is a special guest post from Denise Minger (thank you, Denise!). When fear-inducing news headlines hit the papers (and airwaves and iPads…) –  High-Fat Diet Linked to Breast Cancer, Eating Whole Grains Will Help You Live Longer, Fish Oil Linked to Prostate Cancer – she’s the person to go to for an honest and entertaining critique of the research. In the last week I’ve received an untold number of emails from inquiring Mark’s Daily Apple readers about this latest health news “bombshell”. So, naturally, Denise…

It’s that time again. Your inbox is filling up with emails from your low-fat friends. Your mom left four voicemails ordering you to throw away your bacon now (and clean your room while you’re at it). Your diet-savvy coworker left a Yahoo! News article on your desk, weighted in place with a muffin. This just in: High-fat diets cause diabetes—and researchers have proof, doggonit!

Read More

Join Over 300,000 Subscribers!

Signup and get:

Primal Blueprint Fitness plus 7 other eBooks
7-Day Course on Primal Fundamentals
Special Offers and More!