Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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Tag: hormones

3 Ways to Regulate Insulin That Have Nothing to Do with Food

Today’s guest post is served by a good friend of Mark’s Daily Apple, Dr. Sarah Ballantyne, PhD, or as you might know her—The Paleo Mom.  

Regulating blood sugar levels is a key feature of any health-promoting diet [15, 20] . High blood sugar levels after eating are a major stimulator of reactive oxygen species (ROS), which are chemically reactive molecules that have important roles in cell signaling (the complex communication between and within cells) and in homeostasis (maintenance of a stable environment inside and outside the cell). But ROS are also potent signals for inflammation and stimulate the production of proinflammatory cytokines (chemical messengers), and also injure cells and tissue. As a result, chronic high blood sugar levels can cause serious damage throughout the body, including to blood vessels and vital organs. This is why diabetes (chronical hyperglycemia) is associated with higher risk of stroke, cardiovascular disease, vision problems, kidney disease, and nerve damage.

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Dear Mark: High T, More Wives? Plus Testosterone for Women and the Best Primal Roux

For today’s edition of Dear Mark, I’m answering three questions from readers. First, I respond to a reader wondering which direction the arrow of casuality points in the married Swahili man/testosterone level study I discussed last week. Are high testosterone levels in polygamous Swahili men a cause or consequence of having more than one wife? Second, what’s the deal with testosterone in women? Do they need it as much as men do? And last but not least, what’s the best gluten-free, Primal-friendly flour to use for making a roux?

Let’s go:

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10 Tips to Boost Your Serotonin

Serotonin is a major regulator of mood and depression risk. These are important, vital roles, to be sure. Your mood describes how you experience and interpret the world. If it’s consistently bad, you’regoing to have a rough time. Yet, serotonin is much more than the “feel-good hormone.” It also influences sexual desire and helps us remember. It’s the precursor to melatonin, the neurotransmitter that allows us to sleep.

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Dear Mark: Hiking and Body Composition, Hiding Liver, Unconventional Testosterone Boosters, Cooked/Cooled/Reheated Potatoes, and Sirtuins

For today’s edition of Dear Mark, I’m answering five questions from readers. First up, why isn’t hiking giving one reader the shifts in body comp they expected? Two, is there actually a way to mask the flavor of liver? Then I discuss a few unconventional testosterone boosters, followed by a brief treatment of the cooked, then cooled, then reheated potato. And finally, are there any dietary activators of sirtuin proteins?

Let’s go:

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Dear Mark: Isometrics and Yoga for Seniors, Plus How Aging Affects Recovery

For today’s edition of Dear Mark, I’m answering a few questions about exercising for seniors. Last week’s post drew a lot of comments, and a few questions about how seniors should train. First, I’ll explore isometrics as an alternative for building strength and power. Can you get away with only trying to move weight? Next, I show how yoga can be an effective strength-builder in older adults. Then, I discuss how aging affects recovery. Many people notice that their recovery time goes way up the older they get. I’ve noticed it myself. Why does it happen?

Let’s go:

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Dear Mark: Do I Need to Eat More, Testosterone Levels, HRV and Carbs

For today’s edition of Dear Mark, I’m answering three reader questions. First, if things are going well on a relatively low-calorie intake, should you just keep on keepin’ on or should you increase food intake to “get ahead” of your needs? Next, what’s the deal with a study showing a high-carb diet is better for testosterone levels than a high-protein one? What does this mean for your Primal way of eating? And finally, can an improvement in heart rate variability after a carb refeed indicate a greater need for carbs?

Let’s go:

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Health Perspective for Every Stage of Life: Part 2

Last week I took up the subject of health through the varying stages of life. What does health mean to us? How should we develop it or live it within the scheme of the different stages we go through as logistical events and developmental maturity shift the focus and parameters of our lives? How do our major milestones challenge our approach to well-being? Let’s pick up that topic again and finish off the discussion. I hope you’ll share your own thoughts on how differing stages of life influenced your thinking about health and what approaches fit the times best for you.

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Dear Mark: Ketosis and Testosterone, Dehydration Hormesis, and Isomalto-Oligosaccharides

For today’s edition of Dear Mark, I’m answering three questions. The first one concerns a potentially combative and controversial topic: ketogenic diets. What’s the deal with their effect on testosterone? You can find keto anecdotes across the web both inspiring and flaccid, but what, if anything, does the science say? Next, might there be a way to derive beneficial hormetic effects from acute bouts of dehydration? It seems like every other stressor can actually make a person stronger, so perhaps an otherwise wholly negative one like dehydration might as well. And finally, is the prebiotic fiber known as isomalto-oligosaccharide safe and/or good to eat?

Let’s go:

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Dear Mark: Diet for Alzheimer’s, and the Role of Competitiveness in Modern Life

For today’s edition of Dear Mark, we’ve got just two questions, but they’re meaty ones. The first concerns a new study seeming to claim that all the foods we hold dear on the Primal eating plan — or at least a big portion of them — cause Alzheimer’s disease. Could it be true, or is the study, which is an epidemiological massage of existing data, maybe not quite so definitive as that? Also, what if we had a study showing that exact opposite: that following a Primal lifestyle (not just diet) could actually reverse Alzheimer’s-associated cognitive decline? Then, I discuss the role of competitiveness in life. Having been a top endurance athlete, I know a little bit about the subject. What does it mean these days, though?

Let’s go:

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Why Some Like It Hot

We’ve explored the health benefits of cold (water) exposure. What about heat?

I decided to explore the health benefits of acute heat exposure in the form of saunas, baths, and steam rooms for one main reason: the sauna is a near-universal human tradition, and I’m always curious about those. Indigenous peoples of North America had the sweat lodge, those of Central America the temazcal. The Romans had the thermae, which they picked up and refined from the Greeks. Other famous traditions include Finnish saunas, Russian banyas, Turkish hammams, Japanese sentó (or the natural spring-fed onsen), and the Korean jjimjilbang. Are all these many billions of people across time and space sitting in heated rooms for the heck of it?

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