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Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

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January 15, 2008

Drink up: Red Wine Ingredient Reduces Signs of Aging

By Worker Bee
18 Comments

Finally, the excuse you were looking for to hit the bottle: Researchers from Sirtris Pharmaceuticals this week announced that a derivative of an ingredient in red wine may help reverse the signs of aging!

The ingredient in question is resveratol, a naturally occurring substance in wine, that stimulates a gene known as SIRT1. In previous studies, the SIRT1 gene has been found to increase the lifespan of rodents, but this is the first study to test the theory in humans.

For the study, researchers assigned 67 diabetic patients to receive doses of a proprietary form of the resveratol drug known as SRT501 in either 2,500 or 5,000 milligram (huge amounts) liquid doses. At the end of the 28 day study period, the researchers reported that SRT501 “significantly reduced blood sugar in 67 diabetic patients as compared with a placebo group.” In addition to the positive outcomes, the groups experienced no adverse effects.

Commenting on the high doses needed for the drug to produce significant results, the researchers noted that resveratol was not a very potent molecule. They say, however, that the drug appeared to be five times easier for the body to use than naturally occurring resveratol (so I guess drinking ourselves into oblivion isn’t going to stave off the Grim Reaper after all!) With that being said, they are currently testing other compounds – some of which are 1,000 times more potent than resveratol – to better stimulate the SIRT1 gene.

via Wired Med-Tech

WTL photos Flickr Photo (CC)

Further Reading:

Smart Fuel: Wine

Not Every Vice is a Bad Vice

Dumb Little Man: 8 Straight Benefits of Red Wine

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TAGS:  Aging, prevention

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8 Comments on "Drink up: Red Wine Ingredient Reduces Signs of Aging"

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Judy
Judy
9 years 3 months ago

Ah, now, I think I’ll pour myself a glass on that note!

skylar
skylar
9 years 3 months ago

The healthy ingredient in red wine is resveratrol and resveratrol is a very healthy antioxidant. It is in the Master Formula in abundance, I think fir me that kind of separates this formula from all the others out there.

Randy Thomas
Randy Thomas
8 years 8 months ago
Of course drug companys are jumping on the resveratrol bandwagon, claiming their ‘synthetic’ is far more powerful that the natural…Why? because they cannot PATENT a natural substance to rake-in the profits! As for synthetic versions of natural substances..well known that that natural vitamin E is absorbed 3X better than synthetic, natural estrogen worked great for years until a drug company patented a synthetic version, which caused more side effects. Drug companies fight natural supplements, until evidence becomes overwhelming…Then they tweak a molecule or two, to be able to patent it, and spend millions to promote it, to rake in big… Read more »
oliver
7 years 9 months ago

nice send me more

oliver
7 years 9 months ago

nice i love it

R G
R G
7 years 2 months ago

There’s something called japanese knotweed or maybe knoxweed, and it has much higher levels of resveratol without, of course, the alcohol. Supplement companies extract it from this. I don’t know any particular brands, but I’d certainly prefer this route to wine.

Mike
Mike
5 years 1 month ago

What is your take on Grape seed extract? I buy it from Vitamin Shoppe and it appears to be natural, but now I wonder if I’m getting the maximum bang for the buck.

Ebba
Ebba
3 years 4 months ago

I have seen scin care products containing resveratol as an anti-aging component. Does the skin really absorb it from the outside?

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