Meet Mark

Let me introduce myself. My name is Mark Sisson. I’m 63 years young. I live and work in Malibu, California. In a past life I was a professional marathoner and triathlete. Now my life goal is to help 100 million people get healthy. I started this blog in 2006 to empower people to take full responsibility for their own health and enjoyment of life by investigating, discussing, and critically rethinking everything we’ve assumed to be true about health and wellness...

Tell Me More
Stay Connected
April 05, 2008

Resveratrol Does It Again

By Worker Bee
19 Comments

Seriously, how can we not love this stuff? The potent little antioxidant has been hailed for years as anti-inflammatory, anti-atherogenic and even anti-cancer. And, as for the cancer part, the news just keeps getting better. Research out of the University of Rochester Medical Center shows that resveratrol is doubly effective in treating the exceptionally problematic pancreatic cancer.

[Resveratrol] can help destroy pancreatic cancer cells by reaching to the cell’s core energy source, or mitochondria, and crippling its function. The discovery is critical because, like the cell nucleus, the mitochondria contains its own DNA and has the ability to continuously supply the cell with energy when functioning properly. Stopping the energy flow theoretically stops the cancer. …The new study also showed that when the pancreatic cancer cells were doubly assaulted — pre-treated with the antioxidant, resveratrol, and irradiated — the combination induced a type of cell death called apoptosis, an important goal of cancer therapy. In fact, the research suggests resveratrol not only reaches its intended target, injuring the nexus of malignant cells, but at the same time protects normal tissue from the harmful effects of radiation.

via Science Daily

In the words of lead author, Paul Okunieff, “Resveratrol seems to have a therapeutic gain by making tumor cells more sensitive to radiation and making normal tissue less sensitive.” Resveratrol’s sabotage of the cell’s energy flow is also especially important for chemotherapy because it decreases the cell’s ability to simply “pump” out administered chemotherapy treatment.

The results themselves are fascinating and promising for those who face the difficulty of a pancreatic cancer diagnosis. But we also found ourselves talking about the broader context of this research: the power of a natural antioxidant as a complementary therapy with a conventional treatment.

We talk a lot about the role of exercise and diet/supplementation in prevention here, which makes sense. No one wants to find themselves faced with a critical diagnosis to begin with. But there’s a whole new branch of research unfolding that hopes to harness the best of traditional medicine and nutrient potential. We hope to bring you more along this vein in the future.

In the meantime, send us your thoughts and perspectives.

Homemade Flickr Photo (CC)

Further Reading:

Resveratrol Reduces Signs of Aging

Wine Prevents Cavities

Smart Fuel: Wine

Subscribe to Mark’s Daily Apple feeds

Sponsor note:
This post was brought to you by the Damage Control Master Formula, independently proven as the most comprehensive high-potency antioxidant multivitamin available anywhere. With the highest antioxidant per dollar value and a complete anti-aging, stress, and cognition profile, the Master Formula is truly the only multivitamin supplement you will ever need. Toss out the drawers full of dozens of different supplements with questionable potency and efficacy and experience the proven Damage Control difference!

Subscribe to the Newsletter

If you'd like to add an avatar to all of your comments click here!

Leave a Reply

19 Comments on "Resveratrol Does It Again"

avatar

Sort by:   newest | oldest | most voted
Judy
Judy
8 years 5 months ago

My only thought is where’s my corkscrew?

Jen
Jen
8 years 5 months ago

I’ll drink to that as well. I love it when something truly healthy is also a great way to indulge.

Ryan
Ryan
8 years 5 months ago

So what’s the effective dose of resveratol?? We all wanna know!

Anna
8 years 5 months ago
Sadly, I’m probably going to have to let this great anti-oxidant be a infrequent one. I’d rather get my resveratrol from drinking wine instead of a capsule. But like others have also mentioned in comments on a previous post, I can’t ignore anymore that my tolerance for alcohol is so greatly reduced now. I hadn’t thought about it being due to LC, but that sounds reasonable. Unless it’s at at a party or somewhere really stimulating, one glass of wine at home in the evening will slow me down or put me to sleep on the sofa not long after… Read more »
Sonagi
Sonagi
8 years 5 months ago

Muscadine grapes are very high in resveratrol, and North Carolina Duplin muscadine wine is very affordable at $7.50 a bottle at my local supermarket. A four-ounce glass leaves a mildly sweet taste on the palate after dinner.

Moe
Moe
8 years 5 months ago

Are there any non-alcoholic sources of resveratrol?

Erin
Erin
3 years 2 months ago

grapes and dark chocolate

Derick
Derick
8 years 5 months ago
Resveratrol can help you to lead a long and healthy life so says Dr. Oz. Resveratrol Supplements can help you control your weight naturally by increasing energy, reducing cravings, and limiting your appetite. According to Wikipedia, Consumer Lab, an independent dietary supplement and over the counter products evaluation organization, published a report on 13 November 2007 on the popular resveratrol supplements. The organization reported that there exists a wide range in quality, dose, and price among the 13 resveratrol products evaluated. The actual amount of resveratrol contained in the different brands range from 2.2mg for Revatrol, which claimed to have… Read more »
Nancy S
8 years 5 months ago

I’m in Italy so a good bottle of red wine can be as little as 2 or 3 Euro ($3-5ish). Sign me up!

Doug K
8 years 5 months ago

Nancy, I’m envious.. it seems wine is a lot cheaper everywhere in Europe. In Germany I could get a good S. African red wine for about 5 euro, the same bottle is $10-15 in the USA.

Jean
8 years 5 months ago

I am definetly interested in this superior product but without the alcohol. To actually achieve the results they are talking about, you would need to consume a 1000 bottles of red wine a day. Impossible, right? So check out this website and you can find resveratrol here in its best consumable form.
http://www.marketamerica.com/jeannebauer
health & nutrition, find Isotonix Resveratrol.

trackback

[…] bonus with red? Resveratrol – that super antioxidant, able to combat cancer and reduce signs of aging, among other […]

trackback

[…] bonus with red? Resveratrol – that super antioxidant, able to combat cancer and reduce signs of aging, among other […]

trackback

[…] […]

trackback

[…] Resveratrol gets a lot of publicity for its possible anti-cancer, cardioprotective, and lifespan enhancing qualities, but it’s also gaining steam as a potential photoprotective agent. This study found that once incorporated into skin cells, resveratrol protected them from UV damage. Topical resveratrol seems viable, too, but I can imagine rubbing resveratrol into your sun-exposed skin would get expensive rather quickly. […]

trackback

[…] Resveratrol gets a lot of publicity for its possible anti-cancer, cardioprotective, and lifespan enhancing qualities, but it’s also gaining steam as a potential photoprotective agent. This study found that once incorporated into skin cells, resveratrol protected them from UV damage. Topical resveratrol seems viable, too, but I can imagine rubbing resveratrol into your sun-exposed skin would get expensive rather quickly. […]

trackback

[…] of all, this guy who apparently fabricated a lot of his research on resveratrol, Dipak Das, isn’t the only resveratrol researcher in the world. He’s not even the […]

Gregorio
Gregorio
4 years 8 months ago
The allometric scaling of metabolism models all the results obtained, and the reason for and limitations of caloric restriction’s effects on longevity. It is based upon the electrochemistry and thermodynamics of organic bonds of biomass. It also suggests extant ideas about mitochondrial energy generation and oxidants is preposterous, and that oxidative stress is not an issue in aging, that at the cellular level and smaller oxygen is not an electron donor,but instead an electron acceptor. That means no oxidation, but instead the generation of hydrogen peroxide, the creation of hydrogen and peptide bonds. This is about energy, not chemistry. And… Read more »
trackback
4 years 7 months ago

[…] Wine (organic) – super antioxidant, able to combat cancer and reduce signs of aging, among other feats. Lower carbohydrates the […]

wpDiscuz