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	<title>Comments on: Are New Prescription Drugs Safe?</title>
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	<link>http://www.marksdailyapple.com/prescription-drugs-safety/</link>
	<description>Serving up health and fitness insights (daily, of course) with a side of irreverence.</description>
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		<title>By: NNT (Number Needed to Treat) &#124; Mark's Daily Apple</title>
		<link>http://www.marksdailyapple.com/prescription-drugs-safety/#comment-389181</link>
		<dc:creator>NNT (Number Needed to Treat) &#124; Mark's Daily Apple</dc:creator>
		<pubDate>Thu, 21 May 2009 23:35:11 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=1259#comment-389181</guid>
		<description>[...] ready? Let’s take this thing apart! First off, a bit of review. Some weeks ago we brought you perspective on the “harm-benefit” ratio in pharmaceutical testing. With the myriad of, say, cholesterol targeting drugs out there, you’d think that all that [...]</description>
		<content:encoded><![CDATA[<p>[...] ready? Let’s take this thing apart! First off, a bit of review. Some weeks ago we brought you perspective on the “harm-benefit” ratio in pharmaceutical testing. With the myriad of, say, cholesterol targeting drugs out there, you’d think that all that [...]</p>
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		<title>By: Warming up, etc. &#171; No Magic Pill</title>
		<link>http://www.marksdailyapple.com/prescription-drugs-safety/#comment-251549</link>
		<dc:creator>Warming up, etc. &#171; No Magic Pill</dc:creator>
		<pubDate>Wed, 07 Jan 2009 23:01:33 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=1259#comment-251549</guid>
		<description>[...] Zone Diet, eggs, hot fat (not a fetish site link), exercises to avoid at all costs, prescription drugs, some potpourri, reasons to get out of the gym, and how stress makes you fat (* denotes some guest [...]</description>
		<content:encoded><![CDATA[<p>[...] Zone Diet, eggs, hot fat (not a fetish site link), exercises to avoid at all costs, prescription drugs, some potpourri, reasons to get out of the gym, and how stress makes you fat (* denotes some guest [...]</p>
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		<title>By: Curt</title>
		<link>http://www.marksdailyapple.com/prescription-drugs-safety/#comment-127992</link>
		<dc:creator>Curt</dc:creator>
		<pubDate>Tue, 19 Aug 2008 16:37:50 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=1259#comment-127992</guid>
		<description>There are big problems with our drug development and approval process, but making harder and longer to approve drugs is going in the wrong direction.  I Googled drug developement costs - according to the Congressional Office of Technology assessment it cost $359 Million to get a new drug approved.  Newer figures place the cost upwards of $500 Million.  And the process takes 8 to 12 years.  And, only 1 out 5000 compounds that starts preclinical testing actually make it to market.  We need to overhaul the way drugs are developed and brought to market - and not just add more time and cost to the drug development process.  Unfortunately there are too many vested interests, and way too many lawyers that want to sue drug companies with deep pockets using antiquated laws, for me to see any way to reform the system that would actually work.</description>
		<content:encoded><![CDATA[<p>There are big problems with our drug development and approval process, but making harder and longer to approve drugs is going in the wrong direction.  I Googled drug developement costs &#8211; according to the Congressional Office of Technology assessment it cost $359 Million to get a new drug approved.  Newer figures place the cost upwards of $500 Million.  And the process takes 8 to 12 years.  And, only 1 out 5000 compounds that starts preclinical testing actually make it to market.  We need to overhaul the way drugs are developed and brought to market &#8211; and not just add more time and cost to the drug development process.  Unfortunately there are too many vested interests, and way too many lawyers that want to sue drug companies with deep pockets using antiquated laws, for me to see any way to reform the system that would actually work.</p>
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		<title>By: Methuselah - Pay Now Live Later</title>
		<link>http://www.marksdailyapple.com/prescription-drugs-safety/#comment-126248</link>
		<dc:creator>Methuselah - Pay Now Live Later</dc:creator>
		<pubDate>Sun, 17 Aug 2008 16:16:58 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=1259#comment-126248</guid>
		<description>What drives me nuts is that since the pharmas have the money, they drive the reseach agenda. The wealth of information that collects on this and other blogs has very little impact on what research is done even though the likely impact on people&#039;s lives could be greater than the impact of the bottom-line-drive research they do. &lt;a href=&#039;http://paynowlivelater.blogspot.com/2008/07/are-we-underrating-anecdotal.html&#039; rel=&quot;nofollow&quot;&gt;More on that point here&lt;/a&gt;, if you are interested.

Methuselah
&lt;a href=&#039;http://paynowlivelater.blogspot.com&#039; rel=&quot;nofollow&quot;&gt;Pay Now Live Later&lt;/a&gt;</description>
		<content:encoded><![CDATA[<p>What drives me nuts is that since the pharmas have the money, they drive the reseach agenda. The wealth of information that collects on this and other blogs has very little impact on what research is done even though the likely impact on people&#8217;s lives could be greater than the impact of the bottom-line-drive research they do. <a href='http://paynowlivelater.blogspot.com/2008/07/are-we-underrating-anecdotal.html' rel="nofollow">More on that point here</a>, if you are interested.</p>
<p>Methuselah<br />
<a href='http://paynowlivelater.blogspot.com' rel="nofollow">Pay Now Live Later</a></p>
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		<title>By: Dave in Ohio</title>
		<link>http://www.marksdailyapple.com/prescription-drugs-safety/#comment-126183</link>
		<dc:creator>Dave in Ohio</dc:creator>
		<pubDate>Sun, 17 Aug 2008 14:24:33 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=1259#comment-126183</guid>
		<description>I meant &quot;statins&quot;, not &quot;statics&quot;, of course.  Sorry for the error.</description>
		<content:encoded><![CDATA[<p>I meant &#8220;statins&#8221;, not &#8220;statics&#8221;, of course.  Sorry for the error.</p>
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		<title>By: Dave in Ohio</title>
		<link>http://www.marksdailyapple.com/prescription-drugs-safety/#comment-126173</link>
		<dc:creator>Dave in Ohio</dc:creator>
		<pubDate>Sun, 17 Aug 2008 14:03:09 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/?p=1259#comment-126173</guid>
		<description>I&#039;d say we are all being fleeced, even those of us who don&#039;t take prescription drugs.  A classic case is statics, given to virtually anyone who has their cholesterol checked, and costs about $100 a month.  That&#039;s a lot of healthcare cost right there.  Not to mention it does nothing to help for over 99% of those taking it, but does comes with a plate full of side effects that lowers the quality of life for the patient.</description>
		<content:encoded><![CDATA[<p>I&#8217;d say we are all being fleeced, even those of us who don&#8217;t take prescription drugs.  A classic case is statics, given to virtually anyone who has their cholesterol checked, and costs about $100 a month.  That&#8217;s a lot of healthcare cost right there.  Not to mention it does nothing to help for over 99% of those taking it, but does comes with a plate full of side effects that lowers the quality of life for the patient.</p>
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