As you probably already know, we here at MDA are all about making informed decisions that produce the best results with a minimal amount of effort. For example, what’s the point in running yourself to death when you can achieve better results with a short and intense workout session? In this sense we are all for shortcuts. We love ’em. Why take the long, circuitous path from A to B when you can get there by walking (or sprinting!) a straight line? But we normally discount the effectiveness of pharmaceutical shortcuts. Why? Shortcuts that involve pills usually never work – especially in achieving long term health or fitness goals. Pharma attempts at wellness almost always have a tough time seeing the forest for the trees. Gene expression is much more nuanced enterprise than a pill can account for. In other words, when it comes to popping a pill it is difficult to know what is going on behind the curtain. So when we read about a new pill being developed that chemically mimics the effects of exercise in lab mice, you can imagine how skeptical we were.