Marks Daily Apple
Serving up health and fitness insights (daily, of course) with a side of irreverence.

Mark's Daily Apple

1 Feb

Big Pharma: Bad Science AND Bad Business

As promised, we’ve been hot on the trail of Big Pharma lately, passing along every bit of damning truth we can find. This Sunday’s LATimes carried an article we call an “essential read” for anyone who’s been following and cursing the industry’s exploitation of the American public.

The strategy that has made the pharmaceutical industry one of the wealthiest and most powerful on Earth is finally starting to betray it. Beginning in just a few weeks, and continuing over the next several years, some of the biggest-selling and most profitable drugs in history will lose their patent protection. …The real problem is that the industry’s scientists have hit a dry spell. They are not discovering enough new drugs to replace the aging standbys. Last year, the U.S. Food and Drug Administration approved just 19 new medicines, according to preliminary data, the fewest since 1983. Lost in all the hand-wringing on Wall Street is a recognition of how the industry got itself into this fix in the first place. For 25 years, the drug industry has imitated the basic business model of Hollywood. Pharmaceutical executives, like movie moguls, have focused on creating blockbusters. …The strategy had a flaw that executives have long ignored: It required extraordinary amounts of promotion at the expense of scientific creativity. To make the strategy work, the drug industry put its marketers in charge; scientists were given a back seat. Is it any wonder that executives at many companies have watched their pipelines of new drugs slow to a trickle?

via LA Times

Keep reading…

31 Jan

The Role of Lean Muscle Mass and Organ Reserve in Aging

There’s been a lot in the news lately about the question of longevity. This past week an article discussed the role of exercise in “biological aging,” the relative age of a person based on biomarkers (determined by telomere length in this study), rather than simple chronology.

To add to this discussion, I want to offer up a medically accepted dimension of biological aging that hasn’t gotten as much press lately. Lean muscle mass in happy tandem with organ reserve are two defining characteristics of both good health and longevity.

Have you ever heard someone say that a person died of “old age” or “natural causes”? Essentially, the person died as a result of the logical end of the aging process, the diminishment of organ reserve and corresponding muscle mass that supported his/her physical functioning.

Keep reading…

31 Jan

Research Suggests Exercise Motivation Associated with Body Weight

New research conducted by researchers at Mount Allison University in New Brunswick, Canada suggests that thinner people are more motivated to exercise than their heavier peers.

In a study initially devised to determine how much rats are willing to pay for an opportunity to exercise, the researchers found that slimmer rats were more motivated to work out than their larger peers. In addition, the more weight the rat lost, the more motivated it was to hop on the wheel, so much so that some of the rats in the study quite literally exercised and starved themselves to death (a phenomenon that also occurs in our society in the form of activity- or exercise-anorexia).

Keep reading…

31 Jan

Low Carb, High Protein Diet Reduces Seizure Rate in Epilepsy Sufferers

A study in the February issue of Epilepsia suggests that a low-carbohydrate, high-protein diet can significantly reduce the number of seizures in adult epileptics.

For almost a century, physicians have prescribed low carbohydrate diets to control epilepsy in children. Among the more popular diets is the ketogenic diet, which requires a period of initial fasting, followed by a diet that severely restricts carbohydrate intake and reduces fluid intake.

In the most recent study to test the value of similar diets on adults, researchers from the Johns Hopkins University School of Medicine in Baltimore assigned 30 epileptic adults ranging in age from 18 to 53 year to follow a “modified Atkins diet” that restricted carbohydrate intake to about 15 grams per day. In order to qualify for the program, participants had to have tried at least two anticonvulsant medications without success and have logged an average of 10 seizures per week.

Keep reading…

30 Jan

The Definitive Guide to Cholesterol

That makes it easy.

With all the talk of fighting, battling, combating and beating cholesterol into submission, you’d think it had a black plastic body suit and James Earl Jones’ voice. Big Pharma has, dutifully created quite an arsenal for our supposed defense, and the medical community has been a willing faction, delivering the rhetoric that would incite us all to pick up arms. Now if only we could put down the Big Macs. And the Ding Dongs, HoHos, Twinkies and…you get the point.

Keep reading…

© 2015 Mark's Daily Apple

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