For today’s edition of Dear Mark, we’ve got a three-parter. First I discuss the effect of aloe vera on gut function. Is there evidence that it’s a panacea for intestinal permeability, as so often is claimed? Next, I help an extremely active reader who’s considering switching to one meal a day to lose the last few stubborn pounds of body fat figure out what his next move should be. And finally, I explore the evidence for a connection between the herbicide glyphosate and celiac disease.