For today’s edition of Dear Mark, I’m answering three questions. The first one concerns a potentially combative and controversial topic: ketogenic diets. What’s the deal with their effect on testosterone? You can find keto anecdotes across the web both inspiring and flaccid, but what, if anything, does the science say? Next, might there be a way to derive beneficial hormetic effects from acute bouts of dehydration? It seems like every other stressor can actually make a person stronger, so perhaps an otherwise wholly negative one like dehydration might as well. And finally, is the prebiotic fiber known as isomalto-oligosaccharide safe and/or good to eat?