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	<title>Comments on: Spar of the Day: Taking on MSG</title>
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	<link>http://www.marksdailyapple.com/monsodium-glutamate/</link>
	<description>Serving up health and fitness insights (daily, of course) with a side of irreverence.</description>
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		<title>By: Tom</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-498678</link>
		<dc:creator>Tom</dc:creator>
		<pubDate>Thu, 04 Feb 2010 00:21:15 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-498678</guid>
		<description>In response to commenters, and the section &quot;What does it do to the body?&quot; - No reputable scientific research exists which suggest MSG is anything but perfectly safe.

In short, people who suffer from ill effects they attribute to MSG are consistently unable to reproduce those effects in controlled clinical trials.

Here are two paper abstracts and DOI citations supporting this.

Abstract:
71 healthy subjects were treated with placebos and monosodium L-glutamate (MSG) doses of 1.5, 3.0 and 3.15 g/person, which represented a body mass-adjusted dose range of 0.015–0.07 g/kg body weight before a standardized breakfast over 5 days. The study used a rigorous randomized double-blind crossover design that controlled for subjects who had MSG after-tastes. Capsules and specially formulated drinks were used as vehicles for placebo and MSG treatments. Subjects mostly had no responses to placebo (86%) and MSG (85%) treatments. Sensations, previously attributed to MSG, did not occur at a significantly higher rate than did those elicited by placebo treatment. A significant (P &lt; 0.05) negative correlation between MSG dose and after-effects was found. The profound effect of food in negating the effects of large MSG doses was demonstrated. The common practice of extrapolating food-free experimental results to ‘in use’ situations was called into question. An exhaustive review of previous methodologies identified the strong taste of MSG as the factor invalidating most ‘blind’ and ‘double-blind’ claims by previous researchers. The present study led to the conclusion that ‘Chinese Restaurant Syndrome’ is an anecdote applied to a variety of postprandial illnesses; rigorous and realistic scientific evidence linking the syndrome to MSG could not be found.
http://dx.doi.org/10.1016/0278-6915(93)90012-N


Partial Abstract:
Conclusions: MSG has a widespread reputation for eliciting a variety of symptoms, ranging from headache to dry mouth to flushing. Since the first report of the so-called Chinese restaurant syndrome 40 years ago, clinical trials have failed to identify a consistent relationship between the consumption of MSG and the constellation of symptoms that comprise the syndrome. Furthermore, MSG has been described as a trigger for asthma and migraine headache exacerbations, but there are no consistent data to support this relationship. Although there have been reports of an MSG-sensitive subset of the population, this has not been demonstrated in placebo-controlled trials.
http://dx.doi.org/10.1111%2Fj.1745-7599.2006.00160.x</description>
		<content:encoded><![CDATA[<p>In response to commenters, and the section &#8220;What does it do to the body?&#8221; &#8211; No reputable scientific research exists which suggest MSG is anything but perfectly safe.</p>
<p>In short, people who suffer from ill effects they attribute to MSG are consistently unable to reproduce those effects in controlled clinical trials.</p>
<p>Here are two paper abstracts and DOI citations supporting this.</p>
<p>Abstract:<br />
71 healthy subjects were treated with placebos and monosodium L-glutamate (MSG) doses of 1.5, 3.0 and 3.15 g/person, which represented a body mass-adjusted dose range of 0.015–0.07 g/kg body weight before a standardized breakfast over 5 days. The study used a rigorous randomized double-blind crossover design that controlled for subjects who had MSG after-tastes. Capsules and specially formulated drinks were used as vehicles for placebo and MSG treatments. Subjects mostly had no responses to placebo (86%) and MSG (85%) treatments. Sensations, previously attributed to MSG, did not occur at a significantly higher rate than did those elicited by placebo treatment. A significant (P &lt; 0.05) negative correlation between MSG dose and after-effects was found. The profound effect of food in negating the effects of large MSG doses was demonstrated. The common practice of extrapolating food-free experimental results to ‘in use’ situations was called into question. An exhaustive review of previous methodologies identified the strong taste of MSG as the factor invalidating most ‘blind’ and ‘double-blind’ claims by previous researchers. The present study led to the conclusion that ‘Chinese Restaurant Syndrome’ is an anecdote applied to a variety of postprandial illnesses; rigorous and realistic scientific evidence linking the syndrome to MSG could not be found.<br />
<a href="http://dx.doi.org/10.1016/0278-6915(93)90012-N" rel="nofollow">http://dx.doi.org/10.1016/0278-6915(93)90012-N</a></p>
<p>Partial Abstract:<br />
Conclusions: MSG has a widespread reputation for eliciting a variety of symptoms, ranging from headache to dry mouth to flushing. Since the first report of the so-called Chinese restaurant syndrome 40 years ago, clinical trials have failed to identify a consistent relationship between the consumption of MSG and the constellation of symptoms that comprise the syndrome. Furthermore, MSG has been described as a trigger for asthma and migraine headache exacerbations, but there are no consistent data to support this relationship. Although there have been reports of an MSG-sensitive subset of the population, this has not been demonstrated in placebo-controlled trials.<br />
<a href="http://dx.doi.org/10.1111%2Fj.1745-7599.2006.00160.x" rel="nofollow">http://dx.doi.org/10.1111%2Fj.1745-7599.2006.00160.x</a></p>
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		<title>By: Jessica</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-497017</link>
		<dc:creator>Jessica</dc:creator>
		<pubDate>Fri, 29 Jan 2010 14:40:22 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-497017</guid>
		<description>I&#039;m on-the-go quite a bit, so sometimes it gets hard to find protein sources...I find myself eating packs of tuna and salmon (I know, ew). Some of them contain &#039;broth&#039; as one of the ingredients, and I have recently heard this could be a source of MSG. Does anyone have any input on this? Am I killing myself with packaged meat?</description>
		<content:encoded><![CDATA[<p>I&#8217;m on-the-go quite a bit, so sometimes it gets hard to find protein sources&#8230;I find myself eating packs of tuna and salmon (I know, ew). Some of them contain &#8216;broth&#8217; as one of the ingredients, and I have recently heard this could be a source of MSG. Does anyone have any input on this? Am I killing myself with packaged meat?</p>
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		<title>By: MRS. GILLIGAN</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-251271</link>
		<dc:creator>MRS. GILLIGAN</dc:creator>
		<pubDate>Wed, 07 Jan 2009 15:08:32 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-251271</guid>
		<description>Thank you for posting about MSG it is the main cause of obesity and I have been writing collage papers on it since I found out that I have what doctors call &quot;high intolerance &quot; I say I am allergic I get 4 symptoms: 1. vomiting(since I was 14 when i ate food with &#039;msg&#039; in it) 2. Diarhea 3. weight gain 4.headaches

Since I cut it out of my diet(I DID NOT change my exercise routine) I dropped 5 dress sizes!! in 2 and half months. 

EASY weight loss program!! 8 pounds in a week. 

**Amy food products** are great(especially for mac n cheese lovers)</description>
		<content:encoded><![CDATA[<p>Thank you for posting about MSG it is the main cause of obesity and I have been writing collage papers on it since I found out that I have what doctors call &#8220;high intolerance &#8221; I say I am allergic I get 4 symptoms: 1. vomiting(since I was 14 when i ate food with &#8216;msg&#8217; in it) 2. Diarhea 3. weight gain 4.headaches</p>
<p>Since I cut it out of my diet(I DID NOT change my exercise routine) I dropped 5 dress sizes!! in 2 and half months. </p>
<p>EASY weight loss program!! 8 pounds in a week. </p>
<p>**Amy food products** are great(especially for mac n cheese lovers)</p>
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	<item>
		<title>By: Mark&#8217;s Daily Apple &#187; Blog Archive &#187; Mystery Meat: Imitation Crab</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-34455</link>
		<dc:creator>Mark&#8217;s Daily Apple &#187; Blog Archive &#187; Mystery Meat: Imitation Crab</dc:creator>
		<pubDate>Wed, 12 Mar 2008 15:20:18 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-34455</guid>
		<description>[...] red hues found in real crab meat. In some cases, manufacturers will also add monosodium glutamate (MSG) to help enhance the [...]</description>
		<content:encoded><![CDATA[<p>[...] red hues found in real crab meat. In some cases, manufacturers will also add monosodium glutamate (MSG) to help enhance the [...]</p>
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		<title>By: Mark&#8217;s Daily Apple &#187; Blog Archive &#187; Getting Canned: Is Canned Soup Really that Bad for you?</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-32828</link>
		<dc:creator>Mark&#8217;s Daily Apple &#187; Blog Archive &#187; Getting Canned: Is Canned Soup Really that Bad for you?</dc:creator>
		<pubDate>Wed, 05 Mar 2008 16:19:22 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-32828</guid>
		<description>[...] have led them in recent years to issue tougher label requirements for foods that contain MSG. The debate over MSG is long and varied, and has been covered by us in the [...]</description>
		<content:encoded><![CDATA[<p>[...] have led them in recent years to issue tougher label requirements for foods that contain MSG. The debate over MSG is long and varied, and has been covered by us in the [...]</p>
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	<item>
		<title>By: Tamara</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-24833</link>
		<dc:creator>Tamara</dc:creator>
		<pubDate>Wed, 23 Jan 2008 17:18:10 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-24833</guid>
		<description>Did anyone else notice the angel and devil drawn into the chemical structure of MSG? Very funny...</description>
		<content:encoded><![CDATA[<p>Did anyone else notice the angel and devil drawn into the chemical structure of MSG? Very funny&#8230;</p>
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	<item>
		<title>By: elena mcraven</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-23934</link>
		<dc:creator>elena mcraven</dc:creator>
		<pubDate>Fri, 18 Jan 2008 20:06:00 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-23934</guid>
		<description>i was suffering for years,with all sorts of symptoms. after eating at a asian resterraunt i had severe headaches,diarea,hives,dizines to the point i could not stand. the doctors found nothing wrong with me. thanks to my husband we figured out it was M.S.G. thank god for the internet. now i read lables, but you need to know what your looking for. it is hidden in so many things. my reactions to M.S.G. were so bad that my now 12 year old gets afraid when i eat.she has seen what it can do first hand.</description>
		<content:encoded><![CDATA[<p>i was suffering for years,with all sorts of symptoms. after eating at a asian resterraunt i had severe headaches,diarea,hives,dizines to the point i could not stand. the doctors found nothing wrong with me. thanks to my husband we figured out it was M.S.G. thank god for the internet. now i read lables, but you need to know what your looking for. it is hidden in so many things. my reactions to M.S.G. were so bad that my now 12 year old gets afraid when i eat.she has seen what it can do first hand.</p>
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		<title>By: Anne Galle</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-22883</link>
		<dc:creator>Anne Galle</dc:creator>
		<pubDate>Fri, 11 Jan 2008 22:38:00 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-22883</guid>
		<description>Healthy definitely tastes best!  MSG and aspartame (like Equal or NutraSweet) make me very ill so I&#039;ve learned to read labels, make more nutritious foods at home, and eat out only at restaurants that don&#039;t use MSG.  My allergies, jumpy nerves and headaches have cleared up.  But even for people who don&#039;t have symptoms, it makes me wonder what these excitotoxins are doing to them? Put it this way: my grandkids don&#039;t get fed MSG. Nuff said.</description>
		<content:encoded><![CDATA[<p>Healthy definitely tastes best!  MSG and aspartame (like Equal or NutraSweet) make me very ill so I&#8217;ve learned to read labels, make more nutritious foods at home, and eat out only at restaurants that don&#8217;t use MSG.  My allergies, jumpy nerves and headaches have cleared up.  But even for people who don&#8217;t have symptoms, it makes me wonder what these excitotoxins are doing to them? Put it this way: my grandkids don&#8217;t get fed MSG. Nuff said.</p>
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		<title>By: Robert Jenkins</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-22832</link>
		<dc:creator>Robert Jenkins</dc:creator>
		<pubDate>Fri, 11 Jan 2008 15:40:23 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-22832</guid>
		<description>I used to use Accent on a lot of foods and never got an migrain or any other semptoms. Maybe it depends if your are senitive to it? Also read about it attacking the nerves, don&#039;t know about that. It did make food taste better.</description>
		<content:encoded><![CDATA[<p>I used to use Accent on a lot of foods and never got an migrain or any other semptoms. Maybe it depends if your are senitive to it? Also read about it attacking the nerves, don&#8217;t know about that. It did make food taste better.</p>
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		<title>By: Migraineur</title>
		<link>http://www.marksdailyapple.com/monsodium-glutamate/#comment-22662</link>
		<dc:creator>Migraineur</dc:creator>
		<pubDate>Thu, 10 Jan 2008 17:05:31 +0000</pubDate>
		<guid isPermaLink="false">http://www.marksdailyapple.com/monsodium-glutamate/#comment-22662</guid>
		<description>Oh, yes, migraineurs are generally advised to stay away from glutamate.</description>
		<content:encoded><![CDATA[<p>Oh, yes, migraineurs are generally advised to stay away from glutamate.</p>
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