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December 28, 2011

How to Interpret Advanced Cholesterol Test Results

By Mark Sisson
73 Comments

After last week’s post on interpreting traditional lipid tests, I promised a follow-up post on interpreting the advanced VAP and NMR Lipoprofile tests that provide measurements of particle size and all the various sub-fractions of HDL and LDL particles. I even hinted that it might be worth bypassing the traditional test entirely and going straight to the advanced stuff if you were going to get your cholesterol measured anyway, because of the greater accuracy and more detailed picture of your lipids the VAP and NMR tests provide.

Well, I’m going to have to reevaluate my stance on the matter and rethink that original suggestion. Recent evidence shows and commentary from researchers concludes that the various advanced lipoprotein particle classification tests can produce wildly disparate results on the same samples to the point of rendering them unreliable (sound familiar?), especially if we’re going to be evaluating our health based on the results. A 2009 systematic review found that the available LDL subfraction literature “does not provide adequate data about comparability in terms of test performance to choose one or another method to serve as a standard nor are data on comparability in terms of predicting CVD outcomes.” In short, it could – and probably does – have diagnostic value, but there are no real standards for measurement or analysis that would allow us to use the information. Yet.

The only study with a full text available examined four different methods for testing LDL subfraction size. Authors took blood samples from 10 females and 30 males, all healthy and ranging from ages 23 through 61 years, which were then sent out to the labs for testing. Four samples from each person (taken one after the other without any lag time in between) were sent out. Each lab used a different type of LDL fractionation and particle size analysis:

  1. LDL Segmented Gradient Gel Electrophoresis – separates LDL particles into 7 subfractions by size and shape
  2. Vertical Auto Profile-11, or VAP – separates LDL particles into 6 subfractions by size, LDL-1 (most buoyant) through LDL-6 (least buoyant)
  3. NMR Lipoprofile – separates LDL particles into A (large, fluffy, buoyant) or B (small, dense)
  4. Quantimetrix Lipoprint LDL System (sounds like a drug from a Philip K. Dick novel), or tube gel electrophoresis – analyzes lipoprotein sizes and assigns either a normal (less than 5.5), intermediate risk (5.5 to 8.5), or atherogenic (over 8.5) “LDLSF score”

The results “varied considerably among the methods.” According to tube gel electrophoresis, 79% of the people sampled fell into large, fluffy pattern A LDL, while VAP found that only 8% of samples were pattern A. Both VAP and NMR stuck 54% of the people into pattern B, but tube gel electrophoresis classified just 5% (two people) as pattern B. As for type A/B (a roughly equal mix of small, dense LDL and fluffy LDL), VAP classified 2.5 times more samples as A/B than did tube gel electrophoresis and gradiant gel electrophoresis (NMR doesn’t do A/B). For a nice visual of the discrepancies, check out the LDL phenotype distribution data in graph form.

When all was said and done, the four methods agreed on the classification of a mere three people whose lipids they measured. NMR matched the other methods the most and VAP the least, for what it’s worth.

And while it’s true that LDL-C measurements were very different across the different methodologies (as this graph shows), the within-patient relative measurement of LDL-C was maintained across all methodologies; the same was not true for LDL particle size measurements.

I think determining LDL particle size will be helpful in assessing a person’s risk for heart disease. I just don’t think we can use the tests that are currently available to do it, not reliably at least. Which do you choose – VAP or NMR or one of the electrophoresis methods? According to the data, NMR’s more likely to put you in pattern A than VAP, but that’s an indictment of the variability in accuracy of the various methods. Relying on that is just trying to game the system. It might be more or less reliable than VAP, but we can’t know that yet.

Beyond the traditional lipid tests, however, there is a measure that’s worth looking into: Apolipoprotein B.

Apolipoprotein B is a protein residing in LDL particles. In fact, every single LDL particle has a single ApoB, making ApoB an effective measurement of LDL particle count. By all accounts I could find, ApoB is reliable and accurate. Every LDL particle has one ApoB, and along with TC:HD ratio, ApoB count is a strong predictor of heart disease risk (again, with the caveat that these studies are on populations leading a decidedly unPrimal and highly inflammatory lifestyle). If you have a lot of ApoB, you have a lot of LDL particles, which could mean the LDL receptor activity is down-regulated. Or, it could mean you’re losing weight, which can affect lipid values in multiple ways. Or, it could mean that today was a particularly “high ApoB day” and that getting it tested next week will give a different result – simply due to natural fluctuations. You just don’t know.

What I’d really like to see is a little high-def moving graphical representation of your arterial health. Like, instead of getting a single snapshot of the state of your blood lipids, you’d go into the doctor’s office and strap on a non-invasive device (which, if required for its operation, applies the perfect dose of ionizing radiation to provoke a hormetic response, rather than a pathogenic one) that monitors your blood lipid activity. You’d wear it for maybe a week, during which time it would monitor your blood, download the data, and give you a play-by-play summary of what exactly happened in your body. It would even convert it into visual form, so you could watch a nice Pixar-quality video at the end showing cartoon LDL particles with frowny faces oxidizing (or not), interacting with receptors (or not), happy-faced ones delivering cholesterol to be turned into sex hormones, increasing because thyroid health is compromised and LDL receptors down-regulate, decreasing because they’re making more deliveries to cells (good), decreasing because you had a stressful four days of no sleep and low-nutrient junk food and the resulting systemic inflammation was oxidizing them and they ended up as atherosclerotic plaque and no longer in your bloodstream to be measured. Such a device would be great and truly useful.

We don’t have that (yet), but what we do have, while imperfect, isn’t totally useless. Using a traditional lipid test and ApoB, we can still get clues. Next time we talk about this stuff, I’ll go over some strategies for responding to these numbers – if any response is warranted.

Thanks for reading, and be sure to leave a comment in the comment board telling us of your experience with advanced lipid tests, especially if you’ve had several done using different methods (did they agree with each other?).

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73 Comments on "How to Interpret Advanced Cholesterol Test Results"

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Grokitmus Primal
4 years 9 months ago

This is why we need the Primal philosophy. It helps us cut through the details and BS and puts sensible decisions within the grasp of mortal man. No wonder we’re all so easily baffled by BS.

PaleoDentist
4 years 9 months ago

Many of us are interested in the amount of large , fluffy, buoyant LDL particles vs the less buoyant/dense particles. since the latter are associated with artherosclerosis. I think what ever test was used (no matter how inconsistent the results between various tests) we should stick to one test and track the progress. so far I had 2 tests in the past 12 months, time for a third. is this a plausible strategy???

Arty
Arty
4 years 9 months ago

This is why I focus on triglycerides and VLDL.

EZ
4 years 9 months ago

Its all so irritating, so often these tests they use to prescribe dangerous medications are useless because they cannot get the same results twice in a row! So CW says go ahead and take that messed up medication but we need to advocate for ourselves more and believe them less and this shows that. I think I will just listen to my body more and the doctor less.

Arty
Arty
4 years 9 months ago

Statins do not work on particle size anyways. So if someone has 260 total cholesterol but with 30 triglycerides, most or probably ALL of the particles are billowy, fluffy.

So one would start taking drugs to literally RUIN someones perfect health!

Uncephalized
Uncephalized
4 years 9 months ago

This is why you should focus on the basics: quality food, quality sleep, lots of activity (including plenty of play!), and quality, real-life social interactions with people you care about.

The rest is fluff. Health is quality of life, not a number on a lab test.

Mike
Mike
4 years 9 months ago

That’s right. Mark has gone too deep, so that we don’t have to (Thankyou, Mark).

Paul
Paul
4 years 8 months ago

Amen, do the right things and f**k the
rest!!

Andy
Andy
4 years 9 months ago
Thanks Mark – good info for me. I had a VAP test done after 6 weeks strict primal. LDL 183, Pattern A, HDL 47, VLDL 16, TG 60, LP(a) 4, ApoB 126, Apo AI 129, Apo Ratio is .98. As mentioned above, every single LDL particle has a single ApoB particle, but this doesn’t state which marker is the one to look at – if my ApoB is the right measurement my LDL is lower that expected which means my TC is lower and therefore TC:HD is better. If the LDL is the right measurement, then, well, I’m in trouble…… Read more »
mm
mm
3 years 6 months ago

Andy, I was so glad to hear vitamin E helps lower ApoB!!! I looked at the article you linked but did not see that good information. Do you know if its been shown that plain alpha tocopherol (vit. E) or one with mixed tocopherols, and/or mixed tocotrienols is most useful for lowering ApoB?

Colleen
4 years 9 months ago
Your timing of both these posts was amazing. That day we had just got our results back. since going primal our results went from perfect CW results to not so perfect CW results. I am in the health field and used to interpret results for people in a wellness program and any LDL over 140 I suggested they get it down closer to 100 or else the doc might put them on meds. Now my LDL is 143. I decided from reading these posts and investigating on the web that I am not going to worry, if I am eatting… Read more »
moreporkplease
moreporkplease
4 years 8 months ago

Hi Colleen,

You are wise! Btw, I just watched a Danish special based on a new study that argued none of these numbers mean much for women who still have their periods. This study suggested that the better association was your Omega balance. Women with better Omega balances were thinner and had lower rates of heart issues, but the study only looked at 180 women.

Colleen
4 years 8 months ago

I am old and wise, no longer have those messy ol periods, yay!!!! but traded those in for those damn night sweats and sleepless nites hmmmmmm
Yes, will watch my omega balances, thanks

Issabeau
Issabeau
2 years 7 months ago

Those periods become quite tolerant when on a primal diet.
I used to be in pain to the point of passing out and had my period for 5 days +.

Now I don’t even feel when it starts and they’re gone by the 3rd day evening.

I used to have irregular menstruation, but since primal it’s right on time every 28th day between 8 am-10 am it starts and leaves by the 3rd day around 6-8 pm.
I love it.

Dr.Ron
4 years 9 months ago
I’m so happy you retracted your initial support of these tests. As a physician who sees a ton of these results, especially since I take care of a highly insulin resistant population, I can tell you that discordant results have left both my patients and myself confused. Most importantly they have not added value to using the more standard lipid profile test which as you know can be more refined through the use of non-HDL scores, TC/HDL ratios and TG/HDL ratios as well to evaluate the effects of a primal or low carb diet. When I have patients go primal… Read more »
moreporkplease
moreporkplease
4 years 8 months ago

Ty, Dr. Ron. I also wish Mark would admit women exist. It’s important. Women are different – our numbers are different – these tests apply differently to us – they need to be interpreted differently – but alas in the Paleo world no one will admit that women exist.

We are different! Vive la difference! When will a paleo person speak honestly about women’s health?

Mary Jo
Mary Jo
4 years 9 months ago
This is so frustrating for me, I have been VLC for about 18 months, lost 40# and was on a statin prior to this. I have been off of the statin for 6 months before this test was performed. BTW my HDL increased when I went off of the statin. These are my latest numbers – My doctor can’t interpret these, I have to get an appt with a lipidologist just to find out what this result means. Cholesterol – 299 mg/dl Cholesterol/HDL – 3.4 Crea .62 mg/dl Glucose 105 mg/dl HDL – 88 mg/dl HDL Particles – 42.5 (15332984)… Read more »
Leo
Leo
4 years 8 months ago

Because your HDL is excellent over 60 is very good and your Trig are only 61(150 is considered normal) don’t be concerned, that’s the least of your problems.
Your glucose is a little high if it’s at fasting. Non-Diabetic fasting blood glucose ranges from 70 to 90. Of course no one agrees with these numbers.
For the real information (not ADA) on everything related to diabetes an more check Dr.Richard K Bernstein’s “Diabetes Solution” is worth reading.
Good Health to You~

Mary Jo
Mary Jo
4 years 8 months ago

I am one of those people whose fasting glucose is the highest if the day. My glucose actually goes down after I eat. My A1C number is 4.9

Vasco Névoa
4 years 8 months ago

Mary Jo, I had that problem (reactive hypoglicemia) for about 5 years too. It can get to a debilitating condition, be aware. It is perfectly possible to see the blood glucose go all the way down (way below fasting levels) right after eating, especially when eating a higher glicemic load food like carbs, because your insulin response is disproportional.
I don’t know about you, but in my case the problem was the wrong intestinal flora: I was cured after a full disbiosis (a week of diarrhoea) and recovering with probiotic supplements and foods. (It beats doing fecal transplant!!) 😉

moreporkplease
moreporkplease
4 years 8 months ago

Get off the statins period Mary Jo. Research shows they do nothing – zero, zip, zilch – for women. All these blood numbers have different meaning for women in different life stages – with period, peri-menopause, menopausal.

But no matter what stage you’re in, statins don’t work for women. They just don’t. So get off them ASAP.

Mary Jo
Mary Jo
4 years 8 months ago

As I stated in my post, I have been off of the drugs for 6 months. Since then my numbers have gone astray, LDL rising alot.
That is why I had the particle test done to determine what particle size I have.

Steven
4 years 8 months ago

Your TC and LDL-C could be high if you are one of those people in which long-term VLC diets depress the thyroid. The depressed thyroid down regulates the LDL receptor, keeps cholesterol in the blood for longer and then the liver synthesises more.

Burn
4 years 9 months ago

Interesting that the subfraction tests aren’t so accurate. I just got one done using the gel electrophoresis method, not surprisingly my LDL size was nearly all in the top 2 categories. Can’t wait for the next installment!

Leo
Leo
4 years 8 months ago

Wow, Mark!
Just when I thought I knew “everything” you give a cause to stop and question … At my last doctor visit he brought up the subject of cholesterol (idiotic hoax). I asked him; how’s my triglycerides and HDL ? To which his reply was, very good.

You think I’ll be taking that poison?
For me, I strive to keep my triglycerides 75 or lower the better. HDL 60 of higher, higher the better and A1C under 5, between 4.6 to 4.9 is my goal. A very low carb diet works for me.

BTW I really loved your last book…

Colin Gordon
Colin Gordon
4 years 8 months ago

Thank you for all of this information Mark! I’ve been trying to research VAP and NMR tests for a while and this post was extremely helpful.

I’m a “hardgainer” and have been eating generally 18-24 eggs a day (the best quality eggs I can find). This scared the daylights out of my doctor who recommended that I get my cholesterol tested, but I’d prefer to analyze the results on my own rather than blindly follow someone else’s advice.

Steven
4 years 8 months ago

Very few people looking at research take the ‘dietary cholesterol increases serum cholesterol’ idea seriously. Even the new dietary guidelines for Australians made no mention of it

Bill
Bill
4 years 8 months ago

Age 35, male, 185lbs, low bf%

TC = 506
HDL 30
LDL 450
Tri 131

Paleo 1 year+
http://paleohacks.com/questions/86169/hack-my-ridiculous-blood-work-450-ldl-updated#axzz1hrpZUJug

Should I take statins?

Arty
Arty
4 years 8 months ago

You work out like mad? Then refeed carbs for the muscles?
You do this often?

DThalman
DThalman
4 years 8 months ago

try lowering carbs

Peter
Peter
4 years 8 months ago

@Bill @Mary Jo,
Paul Jaminet at perfecthealthdiet.com did a blog series earlier this year about high LDL on Paleo diets. I highly recommend reading the series.
Best of luck!

Steven
4 years 8 months ago

Apo B is a much better risk factor than LDL-C. LDL-C really plays no part in oxidation and atherosclerosis. Apo B can give you an idea of how many LDL particles you have and therefore the total surface area of the phopholipid membranes. Higher surface areas are exposed to more oxidants. The small, dense may have less cholesterol in more LDL, high surface area. The large, buoyant have more cholesterol in less LDL, low surface area.

rik
rik
4 years 8 months ago

excellent article and series…

Erik
4 years 8 months ago

Great post Mark.

BT
BT
4 years 8 months ago
Great post Mark, I have nothing to say about the tests, but before I went off statins a couple of years ago I did a CAT scan of my heart arteries which revealed I had no plaque that would show up due to the calcium found in fat. The radiation was none too flash but if you need to be sure there is no risk of a heart attack this is the one. •Multidetector computed tomography (MDCT) is used to conduct this examination. There are other reasons than heart disease for a cardiac arrest but this does a good job… Read more »
ellie
ellie
4 years 8 months ago

Can we have more information on the reliability of CAT scans for arterial plaque?

Bodybuilder Meal
4 years 8 months ago

Solid post – I need to get a cholesterol test done or something on general health, even a blood test.

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[…] about this ad : How to Interpret Advanced Cholesterol Test Results | Mark's Daily … Winter storm brewing in SouthwestAn early season winter storm is brewing in the Southwest and is […]

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[…] if you’ve had several done using different methods (did they agree with each other?). Read more: http://www.marksdailyapple.com/how-to-interpret-advanced-cholesterol-test-results/#ixzz1hxr18cYU This entry was posted in cholesterol, heart disease and tagged cholesterol, hdl, ldl, VAP. […]

Alex
Alex
4 years 8 months ago

Great post. Thanks!

Alex
Alex
4 years 8 months ago

Mark,
Have you looked into other ways to measure arterial health? For example, using a tool like the Bio-clip Plus to measure aortic pulse wave velocity? Or the EndoPAT test? Or CIMT ultrasound?
Would love your take on those tests, especially given what you have discovered about the usefulness of the lipid tests.
Thanks.
Alex

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[…] the article here: How to Interpret Advanced Cholesterol Test Results | Mark's Daily …Tags: advanced, follow, interpreting, lipid, lipoprofile, nmr, post, promised, tests, traditional, […]

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4 years 8 months ago

[…] very complete discussion on this type of test, I’m going to refer you to Mark Sisson’s excellent post on the […]

Peter
Peter
4 years 8 months ago
Ughhh, how frustrating. I had a standard panel done last month, numbers came back “high”, so by myself, I went and got both the NMR and VAP profiles down. Just got the results, the interesting thing to note is that my total was 30 points lower, just two weeks after the first test. I need to dig into the results and figure out what they all mean, maybe I’ll post over on the forums to get some feedback. But it’s a bummer to hear that these results could now be meaningless, $195 later 🙁 I love primal living/eating, but do… Read more »
Michele
Michele
3 years 5 days ago

see my comment below

dasbutch
dasbutch
4 years 8 months ago

symbiotic relationships are what makes life thrive here on the globe, earth. if any one species were permitted to expand, it would wipe itself out… everything is in check, life dies for life to live. i.e autotrophs and heterotrophs. isn’t it a great place?
sure glad i’m at the top of the food chain.

dasbutch
dasbutch
4 years 8 months ago

woops, previous post should be on weekend love like

trackback

[…] if you consider my cholestrol levels using a different method (links to one of my favorite primal content websites), I am as healthy as a horse. And in fact, […]

Keith
Keith
4 years 4 months ago

One reason to avoid the VAP test is that once you pay for and take the test, you are on your own to interpret the results. At least I found Atherotech Diagnostic Labs unwilling to discuss results to anyone other than a physician.

Steve
Steve
4 years 3 months ago

I’ve been reading Dr. Peter Attia’s articles on cholesterol, parts 1-7, http://eatingacademy.com/nutrition/the-straight-dope-on-cholesterol-part-vii

From his refresher points, “LDL-P (or apoB) is the best predictor of adverse cardiac events, which has been documented repeatedly in every major cardiovascular risk study.”

It seems to be a very thorough discussion thus far.

Jim
Jim
4 years 2 months ago
Not sure about his conclusion. I eat a VERY similar strict primal diet as Dr. Attia. Have been for 2 years. At 40 years old 5’9″ 170 sub 10% BF, my LDL-P is 2081. According to him I am high risk. So what changes should i make? Eat grains? Take drugs? My TC is 302, HDL 70, Trigs 44, LDL size 21.8 and Small LDL-P 160. Don’t buy into his “theory”. These guys don’t get it. There is no one “marker”. All of our bodies are different and we each have different “healthy numbers” My resting HR is also below… Read more »
Mike C
Mike C
4 years 2 months ago

Hmm so is there a bottom line here? Should I even get one of the three tests? NMR, VAP or GGE?

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[…] accuracy and more detailed picture of your lipids the VAP and NMR tests provide. Read more: http://www.marksdailyapple.com/how-to-interpret-advanced-cholesterol-test-results/#ixzz24Bz3mujI Share this:TwitterFacebookLike this:LikeBe the first to like […]

anthony
anthony
4 years 2 days ago

Well, FWIW, after one year of Wheat Belly, and I mean assiduously followed, along with x1 per week HIT with the addition of x1 per week Japanese Sword , every single one of my NMR parameters, save for triglycerides, was “worse” than the previous measurement. Same lab on each measurement occasion.

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[…] How to Interpet Advanced Cholesterol Test Results – Once you finally convince your doctor to order the tests, here’s how to figure out what’s going on. […]

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3 years 9 months ago

[…] How to Interpet Advanced Cholesterol Test Results – Once we finally remonstrate your alloy to sequence a tests, here’s how to figure out what’s going on. […]

Sally
Sally
3 years 8 months ago
Had particle size test done, but I find it difficult to comprehend results. I need to know if I need to see a preventative medicine cardiologist. Thanks. LDL Particle Number (NMRLIP) 1674 nmol/L (NOTE) — REFERENCE VALUE — Low: 2000 LDL Cholesterol (NMRLIP) 96 mg/dL (NOTE) — REFERENCE VALUE — Optimal: 190 HDL Cholesterol (NMRLIP) 50 mg/dL (NOTE) — REFERENCE VALUE — Desirable: >= 40 Triglycerides (NMRLIP) 96 mg/dL (NOTE) — REFERENCE VALUE — Desirable: <150 Total Cholesterol (NMRLIP) 165 mg/dL (NOTE) — REFERENCE VALUE — Desirable: 34.9 Intermediate: 34.9 – 26.7 High Risk: <26.7 Small LDL-P (NMRLIP) 951 nmol/L… Read more »
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[…] How to Interpret Advanced Cholesterol Test Results | Mark's Daily Apple A lot of the tests we get that are similar don't produce similar results according to Mark Sisson on the link above. Here's another site: https://www.directlabs.com/resources…s/default.aspx And one more:VAP Cholesterol Test – The VAP Cholesterol Test Detects High Cholesterol google_ad_client = 'ca-pub-7147593545947707'; google_ad_channel = '1500886191'; google_override_format = 'true'; google_ad_width = 600; google_ad_height = 250; google_ad_type = 'text_image'; google_color_link = '#0000CC'; google_color_url = '#990100'; google_language = 'en'; google_ad_region= "test"; __________________ View hitcheca's full Diabetes Forum profile here. […]
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[…] back to the numbers themselves. They tell a story – a large part of your story. That said, know the numbers you should prioritize. Bond over lab sheets. Talk technical stuff where it’s […]

Michele
Michele
3 years 5 days ago

What everyone should be most worried about are their homocysteine and/or hs-CRP levels, both of which measure the inflammation in your body – the main culprit of CVD. Without a high inflammatory process, your blood vessel lining is good to go and your cholesterol values don’t mean a thing. Most persons observing a Paleo lifestyle should have very good homocysteine and/or hs-CRP levels. If not, then you can investigate your LDL particle sizes.

trackback

[…] if you consider my cholestrol levels using a different method (links to one of my favorite primal content websites), I am as healthy as a horse. And in fact, […]

Anthony
2 years 8 months ago
As a layman I am trying to grasp the value of the LMR test. I ordered it on my own and I need assistance. I already did the test ratio of TG/HDL 78/55 = 1.3 Sounds good right? Here is LMR report: NMR report shows; LDL-P = 2108 High LDL-C = 171 High HDL -C = 55 TG = 72 Small LDL-P = 588 High TC = 240 HDL-P Total = 29.2 Low LDL size = 21.1 HDL size = 8.6 Low LP – IR Score = 37 Ref Range less than 45 So I am confused. Sounds like a… Read more »
Anthony
2 years 8 months ago

Sorry that was NMR Lipid Profile Test Above.

Carol Gillespie
Carol Gillespie
2 years 8 months ago
Hello! I am a 62-year old woman with the following blood lipids results: Total C = 296 HDH = 66 LDL = 216 Tri – 71 My Tri/HDH-C ratio is .93 so this is pretty good – right? My VAP scores showed a total HDL of 71, with only 19 mg/dl composed of large HDH particles. Close to 52 mg % of total was HDL-3 – smaller and more dense , less protective particles. What about the size of my LDL’s? I follow a very low-carb eating style and feel great- even with my hypothyroidism! I went off statins after… Read more »
paleocrush
2 years 8 months ago
what your doctor needs to look at is non-LDL cholesterol because it’s a better predictor of cardiovascular risk than the rest of the lipid panel. most doctors ignore that number (non-LDL) because they were never taught what it means. it’s all the intermediate particles (size-wise). cholesterol is like a passenger that can either get into either an LDL “car” or an HDL “car”. the problem is not so much the number of passengers but the number of cars — i.e. particle number (LDL-P). you may have high cholesterol but a low particle number. cholesterol is an outdated way of looking… Read more »
paleocrush
2 years 8 months ago

argh 🙂 it was late indeed! by non-LDL I meant non-HDL, of course. (need to quit staying up late)

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[…] levels of cholesterol are fairly consistently associated with lower risks of all-cause mortality, in both women (PDF) and […]

J D
J D
2 years 4 months ago

Had two tests done on same blood sample & same day and sent to separate labs. LDL 89 or so on one lab and 197 on the other! LDLP BAD 2400 or something.

BUT, I have APO-E 2/2 and that is really bad for carbs/sugar. APO-E should be checked.

RKV
RKV
2 years 1 month ago

Kindly suggest on my problem
Age – 36 , Male & I am Veggi

TCholesterol – 284
LDL – 204
HDL – 49
TG – 205
LDL/HDL =4.2
TC/HDL = 5.8
VLDL = 42
GGT = 83
SGPT = 58
Dr asked me to take first Udilive -300mg and then go for test. I did the same above is the result( not much changes ) what i should do now. I am worried at a lot.
Following proper cholesterol free diet since last 2 months.

Christina
Christina
1 year 3 months ago
Hi my name is Christina and I’m a 41 year old mom of 6 kids (2 natural, 4 c-sections) I was finally diagnosed last year with severe Hashimoto’s, Fibromyalgia and Celiac disease by a Naturopath after years of Dr’s telling me my uncontrollable weight gain and numerous other symptoms were all in my head and kept pushing me to take antidepressants. We’ve since discovered a strong genetic link as my Grandmother, Mother, Aunt, and sister all have since been diagnosed with Hashimoto’s and various autoimmune diseases by their Dr’s. since my diagnosis. I have been gluten free for a year,… Read more »
Dave Sill
Dave Sill
1 year 3 days ago

Any update on advanced lipid testing? Is it ready for prime time?

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