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  1. #211
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    Quote Originally Posted by ChocoTaco369 View Post
    You understand you're arguing with yourself, right? You understand that just like you can modify your "CI," you can modify your "CO" too, right? I can't spend all day arguing with someone that won't listen, or worse, knows it but just wants to cause problems.
    Given a change in "CI"
    Your body will modify "CO" for you,
    I told you that over 8 months ago

    that's what your thyroid is for.


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    Last edited by dilberryhoundog; 10-14-2013 at 11:01 AM.
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  2. #212
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    Quote Originally Posted by dilberryhoundog View Post
    No excessive circulating FFA's are the RESULT of insulin resistance and more so T2 diabetes.

    What happens is the body is still running glucogenisis and lipolysis (releasing FFA's and glucose) even tho BG had been spiked by a carb meal. A person with IR has a delayed insulin response, the insulin can't turn off lipolysis if it's not there. .

    Medbio/insulin & glucagon (Google it I can't link it on my phone)


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    Not really. the effects of excess FFAs on the insulin receptor mediated signaling pathways in adipose tissue, liver, and skeletal muscle as well as the pro-inflammatory status induced by the toxic effects of excess FFAs in the liver and adipose tissues cause insulin resistance. The FFA induced down regulation of insulin signaling pathways results in activation of several kinases involved in stress response; such as JNK, and suppressors of cytokine signaling-3. JNK activity is also regulated by FFAs and is an important regulator of insulin resistance.

    See: Randle cycle
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  3. #213
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    Quote Originally Posted by dilberryhoundog View Post
    Given a change in "CI"
    Your body will modify "CO" for you,
    I told you that over 8 months ago

    that's what your thyroid is for.


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    So as long as my thyroid is functioning fine, my CO will automatically meet my CI? So I should be able to eat 5,000 calories a day and it'll maintain the same weight as if I eat 2,500 calories a day? The thyroid just negates 2,500 calories out of nowhere?
    Don't put your trust in anyone on this forum, including me. You are the key to your own success.

  4. #214
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    Quote Originally Posted by Derpamix View Post
    Not really. the effects of excess FFAs on the insulin receptor mediated signaling pathways in adipose tissue, liver, and skeletal muscle as well as the pro-inflammatory status induced by the toxic effects of excess FFAs in the liver and adipose tissues cause insulin resistance. The FFA induced down regulation of insulin signaling pathways results in activation of several kinases involved in stress response; such as JNK, and suppressors of cytokine signaling-3. JNK activity is also regulated by FFAs and is an important regulator of insulin resistance.

    See: Randle cycle
    Of course it's gunna be stressful, their BG levels are off the charts.

    Did you google the medbio site, it's written by a professor of biology.



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  5. #215
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    Quote Originally Posted by dilberryhoundog View Post
    Of course it's gunna be stressful, their BG levels are off the charts.

    Did you google the medbio site, it's written by a professor of biology.



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    I will now
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  6. #216
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    Quote Originally Posted by ChocoTaco369 View Post
    So as long as my thyroid is functioning fine, my CO will automatically meet my CI? So I should be able to eat 5,000 calories a day and it'll maintain the same weight as if I eat 2,500 calories a day? The thyroid just negates 2,500 calories out of nowhere?
    Nope that will make you fat, if you eat 1500 cals and you normally burn 2500 your thyroid will turn you down to a CO burning somewhere close to 1500 eventually.

    Hypothyroid has much more room to move than hyperthyroid


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    Last edited by dilberryhoundog; 10-14-2013 at 11:21 AM.
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  7. #217
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    Quote Originally Posted by dilberryhoundog View Post
    Nope that will make you fat, if you eat 1500 cals and you normally burn 2500 your thyroid will turn you down somewhere close to 1500 eventually.

    Hypo has much more room to move than hyper

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    I cannot figure out what you're trying to say at all.
    Don't put your trust in anyone on this forum, including me. You are the key to your own success.

  8. #218
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    Quote Originally Posted by Derpamix View Post
    I will now
    Read the section on "diabetes, development and causes"


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  9. #219
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    Quote Originally Posted by Derpamix View Post
    I will now
    Of course there will be a marked increase in circulating FFAs with the complete absence of insulin and the increased rate of lipolysis. It didn't touch on a cause though, as I did. In this case it's a never-ending stress cycle with the increased FFAs from insulin resistance further atrophying b cells.
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  10. #220
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    Quote Originally Posted by dilberryhoundog View Post
    Read the section on "diabetes, development and causes"


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    Oh, I only saw: Diabetes; metabolism in the absence of insulin.
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