I canít imagine how DRís replacing some of his fruit intake with sugar would increase his BUN and transferrin saturation. Do you have an explanatory mechanism for your hypothesis on that?
I think youíre probably right re: DRís triglyceride numbers and it reveals how amazingly complex diet, the human body and nature in general are.
Here are some of Harley's suboptimal numbers that I noticed:
- low B12 ("Vegetarians, vegans and the elderly are at high risk of developing vitamin B12 deficiency through changes in their diets, according to a review of scientific studies"--http://www.medicalnewstoday.com/articles/263626.php, which low HCL in the stomach can contribute to--http://ods.od.nih.gov/factsheets/VitaminB12-QuickFacts/; DR is using B12 injections to compensate)
- low chloride
- high bicarbonate (can be caused by chloride depletion, which his numbers show, due to deficiency in acidic gastric juice (HCL) http://www.anaesthesiamcq.com/AcidBaseBook/ab7_2.php; which is a symptom of pernicious anemia, which fits with his numbers and which Harley has reported having)
- usually low protein and low urea (indicating that he is not consuming much bioavailable protein)
- low zinc (which can contribute to oxidative stress and low testosterone)
- suboptimal testosterone
- elevated folate - an indicator of inflammatory bowel disease (DR reported having Crohn's disease in the past)
- sometimes high phosphate (an indicator of oxidative stress)
- sometimes low transferrin saturation with moderate ferritin (an indicator of oxidative stress)
- low cortisol (an indicator of adrenal insufficiency, which can occur with chronic oxidative stress)
- usually elevated lactate dehydrogenase (possibly due to his long-distance biking)
(Note: I'm not saying that the above illness indications necessarily mean that DR has them to the extent that they would be clinically diagnosed. Further investigation would be needed and it would be helpful if we could see all his numbers over time to get a better sense of which are flukes and which are chronic issues.)