I think you mean gout right? But yeah, neither of those are very comparable to the mechanisms associated with celiac disease or gluten intolerance. And yes you have to include gluten intolerance and gluten allergy in your projections. Like I said.... read my replies in the linked thread on this. I don't think you did, or you wouldn't had made that absurd comment on lactose intolerance. So in the case of grains that is my primary concern and as to the evidence to support it.... it is ample IMO.
As to burden of proof.... the epidemiological data I asked you to look for doesnt count? I'll get you started.
Cassidy CM. Nutrition and health in agriculturalists and hunter-gatherers: a case study of two prehistoric populations. in Nutritional Anthropology. Eds Jerome NW et al. 1980 Redgrave Publishing Company, Pleasantville, NY pg 117-145
This study is blogged about here if you can't find the original:
Nutrition and health in agriculturalists and hunter-gatherers » The Blog of Michael R. Eades, M.D.
By no means is this the nail in the coffin on grains, but in combination with what I have already written on gluten and our problems with GMO dwarf, and other epidemiological evidence.... well make up your own mind as to if it is worth eliminating for 30-60 days and finding out if you are one of many that are affected.
So thats grains for you. They exist on a continuum of least likely to be detrimental to most likely and you have to take into account cultivation and preparation. There is ample evidence that as humans they are not necessary for health, and in fact epidemiological evidence seems to support the concept that societies that do not include them are healthier than those that do.
As to PUFA... this is getting long again and I'm now off for a hike, but lets just start with a point that SFA has for the most part been vindicated. So maybe the onus of this one is on the people stating that PUFA should need to replace SFA to make us healthier? I mean this is a concept born of the Key's crap 50+ years ago and the heart health hypothesis. We can pick this up in a bit though. BTW have you tried the search function at the top? Perhaps you can do some reading while I'm gone... this really has all been covered before, which is what makes the whole argument a bit redundant....here is a start for you again:
Is It All Just a “Paleofantasy”? | Mark's Daily Apple
Polyunsaturated Fats: Are They Healthy? | Mark's Daily Apple