In the Ancestral Health videos (search youtube) there are many talks on the effects of inflammation. Mark also has a good number of blogs. Sorry I don't have references. In general, Inflammation prevents the stomach, colon, etc from absorbing the nutrients you feed yourself, either in foods or supplements. It also prevents the saiety signals from occuring. You eat more and become obese but at the same time you become malnurished from lack of nutrients. Simultaneously you will probably develop either autoimmune diseases or gut diseases.
"When the search for truth is confused with political advocacy, the pursuit of knowledge is reduced to the quest for power." - Alston Chase