What makes you feel like you have inflammation issues? A true paleo diet is rather anti-inflamatory and shouldn't be causing any issues. Can you provide some more detail?
Honestly protein powder is not the best choice for giving your digestion a "break". If your having digestion issues why don't you try adding some digestive enzymes and HCL to your regime to increase stomach acid and overall digestive health. I'd also consider adding in some fermented foods like kraut into your diet to help boost your healthy gut bacteria (also will help with immune function and inflammation).