There is so much confusing/conflicting info out there I don't know if I should be worried or not. Sifting through everything, I tend to believe Chris Masterjohn has the best theory. Unfortunately, there is not much we can do to increase LDL receptor activity. We can up regulate thyroid with supplements which may help some people. We can take statins which do increase receptor activity but have bad side effects. We can reduce oxidative stress with lifestyle changes. We can eat healthy foods which contain broad-based anti-oxidants like grass fed organ meats and eggs. I am not going to waste my money on a standard lipid panel because I do not believe the cholesterol numbers mean much of anything. Also, I agree with Masterjohn that LDL particle count and particle size tests are not sufficiently developed/standardized and it is not clear that either measurement adds much predictive value. I do believe high blood sugar is a major source of oxidative stress and I have eliminated that problem by going to a VLC, medium protein diet. Before I made the diet changes, I would guess my BG shot up above 200 after my carb heavy breakfast and stayed around 200 pretty much all day long. I now never let my 1 hour postprandials exceed 135-140. My weight is ideal and I have a vigorous exercise program. I am doing everything I can do except take statins which I am not going to do. My goal is to die healthy.
Originally Posted by Dirlot
Last edited by Artbuc; 11-12-2012 at 02:07 AM.
I wasn't writing particle size off as useless. Just pointing out it isn't as set in stone as some people have made it out to be. Some people (not referring to you) tend to pick and choose when it comes to what they believe is the most important parts of lipid panels if it fits their diet bias. I've even heard large particle size being referred to as "non anthropogenic" which just isn't correct.
Originally Posted by magicmerl