For your perusal.

Which brings me to a fascinating new paper by Ian Spreadbury of the Gastrointestinal Diseases Research Unit at Queen's University in Ontario, Canada. It provides what I believe could -- and probably should -- become the dominant index for deciding which foods to eat and which to avoid in pursuit of weight control. Bearing the daunting title, "Comparison with ancestral diets suggests dense acellular carbohydrates promote an inflammatory microbiota, and may be the primary dietary cause of leptin resistance and obesity," the paper lays out the hypothesis that carbohydrate density is probably the most important determinant of whether a food promotes inflammation/obesity or not.

...

Modern food processing is, unfortunately, very good at boosting carbohydrate density. Two of the most powerful ways to do it are isolating and concentrating sugars from plants, and grinding dense seeds into highly compactible flour. In both cases, heat and pressure damage or obliterate the original food's cell walls. To use Spreadbury's terminology, sugar and flour are acellular -- almost wholly lacking in intact cells.