Clinical context.... for the large majority of people cholesterol is a worthless number. I would consider anything from 140-300 within normal limits. As you probably realize this is debatable and is my own opinion based on current evidence. Each person is an individual and wile 150 may be fine for one person it could be the culprit for depressive disorders in another. Also recognize that total cholestorol can vary by up to 30 points from one test to the next so you would need repeated draws just like with BP. Currently the best evidence seems to be pointing towards LDL particle number and inflammatory markers such as CRP for evaluating risk.