
Originally Posted by
Health Divas
I see we are getting mixed responses regarding women and fasting. Ori Hofmekler wrote this:
Female-specific responses to fasting raise an interesting scientific phenomenon. Researchers have been finding evidence that there is indeed a tradeoff between virility and longevity of organisms.
Apparently the same genes that promote human longevity may trigger biological mechanisms that suppress female reproductive capacity.
Hence, fasting and intense exercise protocols, known to promote longevity, also lower estrogen level and thereby modulate body composition and suppress female reproductive capacity. This is apparently part of an early adaption mechanism to primordial conditions of food scarcity and hardship, which requires increased strength and durability on the account of reproductivity. Hence, hard conditions are not biologically suitable times for pregnancy and child bearing.
I discussed this issue with Dr. Marc Mattson, Prof. of Neurosciences at Johns Hopkins University a few years ago. According to Mattson, women who fast or are on calorie restriction, have the tendency to get leaner, become increasingly addicted to physical exercise, and lose their menstrual cycle. Nonetheless, they seem to gain substantial improvements in all main biological markers of longevity – i.e. increased insulin sensitivity, increased GH secretion, improved lipid profile, improved anti-inflammatory cytokine profile, improved cognitive function, etc.
Note that fasting triggers the longevity gene SIRT-1, which regulates mitochondrial energy production along with the gene transcription promoter protein PGC-1α, which increases mitochondrial biogenesis and density in the muscle. Yes, mitochondrial energy utilization efficiency is a key to longevity.
One of the most notable benefits of fasting is its profound anti-inflammatory effect. Fasting increases production of anti-inflammatory cytokines while suppressing pro-inflammatory cytokines such as TNF-α and IL-6. Note that pro-inflammatory cytokines produced by fat cells (adipokines) are associated with insulin resistance, obesity, metabolic syndrome, and a shorter life span; whereas anti-inflammatory cytokines, such as adiponectin and IL-15, are associated with improved insulin sensitivity, increased thermogenesis, decreased fat storage, increased muscle regeneration and increased life span.
Finally, in view of the current epidemic of excess estrogen in females and males, caused by estrogenic chemicals and foods (such as petrochemicals and soy), fasting and IF can be used as an effective therapeutic strategy to balance estrogen and prevent related metabolic disorders and cancer.
Summary Points
Don't blindly trust human studies on IF as some of these show misleading results due to major design flaws.
Don't even think about intermittent fasting if you eat the typical American portions of high glycemic junk food.
When following an IF regimen you need to make it low glycemic and high in protein and fiber. Eat whole foods, possibly high in dairy and whey protein, along with nutrient dense antioxidant foods.
Adjust your fuel food according to your specific condition and type of training.
Your intermittent fasting regimen must make sense. The length of your fasting intervals should be optimized to yield maximum biological impact. What really counts is your net fasting time (period between meals minus digestion time.) It takes your body roughly 5-8 hours to fully digest a meal and shift into a fasting mode. Three to six hours of "not eating" between meals will not be sufficient to put your body in a fasting mode and therefore will fail to get you the results you're looking for.
The female-specific response to fasting or intermittent fasting is no different than the female response to intense exercise. There is indeed a tradeoff between benefits and side effects. And the question "should women fast" raises the same issues as the question "should women exercise intensely".
Do you ladies agree with this????????????