I read through Griff's threads and one of them pointed to this article: Better Know Your Triglyceride/HDL Ratio if You Want to Prevent a Heart Attack
The article indicates that the most important indications for heart desease are HDL/TC and tri/HDL. My numbers are .26 and .60 respectively. These are considered ideal.
So how is my health at risk?
I already understood that ratios are "more" important than TC . This is stated in various articles. However, I'm concerned that even though TC is perhaps "less" important, that it could still be a risk factor if it gets too high. As I see my TC creeping closer to 300, I'm concerned. Kniffgill said that above 400 could be a risk factor, but I cannot confirm this.
I'm trying to figure out if TC, by itself, provides any meaningful information at all. At what point, if any, is high TC a concern?
That's what I'm trying to figure out. Your ratios are fantastic. Get a more detailed test (I think it's called a VAP test?). Get a direct measurement of your LDL, because low trigs can throw off the calculation. And find out whether your LDL is Pattern A or B. I'm guessing with your HDL and trigs where they are, that your LDL is the fluffy, bouyant type (I'm pretty sure that's Pattern A), which is benign.
It does look like a pattern of rising TC, but there's some debate as to whether that is as important as the other factors. There are parts of your diet you can dial in to bring it back down, which have been posted by people who know more about it than I do.
You say fluffy LDL is benign with great authority but no one knows this for sure. Peter Attia presents compelling evidence that it is total LDL-P which drives CVD regardless of particle size. Here is a quote from his blog:
Begin Quote
Summary
At first glance it would seem that patients with smaller LDL particles are at greater risk for atherosclerosis than patients with large LDL particles, all things equal.* Hence, this idea that Pattern A is “good” and Pattern “B” is bad has become quite popular.
To address this question, however, one must look at changes in cardiovascular events or direct markers of atherosclerosis (e.g., IMT) while holding LDL-P constant and then again holding LDL size constant.* Only when you do this can you see that the relationship between size and event vanishes.* The only thing that matters is the number of LDL particles – large, small, or mixed.
“A particle is a particle is a particle.”* If you don’t know the number, you don’t know the risk.
End Quote
Last edited by Artbuc; 08-08-2012 at 02:45 PM.
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