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Thread: LDL at 357 ng/dl, young, lean athlete on Paleo 7 years page 2

  1. #11
    chingu's Avatar
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    I would like to make an update to this thread about how my doctor is wrong for saying I need to go on statins immediately to prevent another attack of acute pancreatitis.

    Issues in Hyperlipidemic Pancreatitis : Journal of Clinical Gastroenterology The research here shows that cholesterol has no relation to acute pancreatitis. I always had this feeling because I had researched acute pancreatitis thoroughly and had seen no case related to high cholesterol levels (only hypertriglyceridemia) but this research says so outright and has been cited almost 400 times.

    Take your doctor's advice with a grain of salt and always research for yourself.

    Now I'm going to further investigate the atherosclerotic issue, which I was less worried about because it is a longer time horizon issue. Still, I'm left wondering why I had that nearly fatal attack of pancreatitis.

  2. #12
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    Do you have any of these risk factors?

    Acute pancreatitis: MedlinePlus Medical Encyclopedia
    Using low lectin/nightshade free primal to control autoimmune arthritis. (And lost 50 lbs along the way )

    http://www.krispin.com/lectin.html

  3. #13
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    I am also somewhat curious about my doctor's insistence that I have genetic familial hypercholesterolemia because I know my mother has decent cholesterol levels, and I haven't spoken to or seen my father but his doctor was more worried about diabetes than heart disease, many years ago.

    The mutation on the LDLRAP1 is autosomal recessive so it could be possible that neither of them had it, but almost all cases of familial hypercholesterolemia are the result of autosomal dominant allele making it very likely I do not have it. The Canadian medical system makes it hard to get this kind of testing done, so I'm going to go with 23andme at some point.

  4. #14
    chingu's Avatar
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    Quote Originally Posted by jammies View Post
    Do you have any of these risk factors?

    Acute pancreatitis: MedlinePlus Medical Encyclopedia
    I didn't read the link, but I don't drink alcohol, have never had gallstones (that I know of) and I highly doubt my triglycerides were elevated extremely high. The bouts of acute pancreatitis all happened on days where I did intermittent fasting and broke the fast with an enormous meal though, and I did not get my triglycerides checked when I was hospitalized. According to my recent test they are much too low to get pancreatitis from though. I have none of the symptoms of hyperparathyroidism. The rest of the causes are extremely rare.

    There is no figuring out how you got your pancreatitis with the state of medical science around it today, for about 10-20% of cases. 10-20% of cases are just labelled idiopathic and that's it. Usually people don't experience another bout. I haven't had abdominal pain since the three cases I had in the span of two weeks, several months ago.

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    My total cholesterol is 327, with my LDL at 231. I have been diagnosed with FH, but my case is a little unusual, as I was adopted and do not know my bio family's medical history. My cholesterol was first tested when I was 6 years old, and my total was nearly 400. I was given the FH diagnosis based on having such high levels at a young age. This was in the early 90's, so I was put on a low-fat diet. My total cholesterol went down into the high-200's until I went on Paleo last year, and then it shot back up (which may have been due to diet, or simply getting older, I was told).

    The results of my most recent lipid panel showed that my LDL particles are large and "fluffy", which is a good thing. My C-reactive protein results showed average, meaning I am not presenting with inflammation. So, for now I am waiting it out, and seeing if dietary/exercise tweaks will help lower my LDL enough for me to feel safe. I'm also working on modifying my diet to cut down on saturated fats, which I have read may process in the body differently for those with FH.

    I did go on statins last year for 1 month. I can't remember which one, because it was a generic, and I don't remember the name. After 30 days, I had my bloodwork done again, and I had only a tiny drop in my numbers. did not have side effects, but it was a low dose, and one of the "weaker" statins. My cardiologist prescribed a new, stronger statin, but I never took it. I really am nervous about neurological side effects. I have an appointment next month to re-check my numbers, and have the statin debate again.

    There is so little research on FH, it makes this all so difficult. Although I do believe that high cholesterol is not a big issue for most bodies, it is still unclear to me on how it differs in those with FH.

  6. #16
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    Another possibility (other than FH) is hypothyroidism. Definitely get a full thyroid panel (TSH, T4, T3, rT3). TSH and T4 alone won't tell you anything, so make SURE you get all of those tests. I asked for a full thyroid panel when my doctor was away and only got T4 and TSH, so don't make the same mistake I did.

  7. #17
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    Yes she has genetic FH. Her numbers are almost always over 300.

    I'm in Canada too, you just have to push your doctor to get you the testing you want. If you're in an urban area, go see a specialist.

  8. #18
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    Quote Originally Posted by yodiewan View Post
    Another possibility (other than FH) is hypothyroidism. Definitely get a full thyroid panel (TSH, T4, T3, rT3). TSH and T4 alone won't tell you anything, so make SURE you get all of those tests. I asked for a full thyroid panel when my doctor was away and only got T4 and TSH, so don't make the same mistake I did.
    Thanks. I got TSH only and it didn't suggest anything. I'll press my doctor on this.

    My thyroid levels are probably temporarily low right now because I am dieting rather dramatically. I was just doing a protein sparing modified fast for about a week and then I transitioned into a little bit higher calories.

    Is it T3 that plays the most important role in regulation of LDL?

  9. #19
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    My doctor believes I have FH, and if I don't have FH my cholesterol levels are high, so either way I should go on statins. I would like a genetic test to determine I have FH and what subtype. However it is hard getting my doctor to budge on spending the government money for the test (Canada) because he believes that the treatment either way will be the same. Does anyone know if there are differences in treatment approach to extremely high cholesterol that is non-FH, and FH? Or between the different FH subtypes?

    There are three main types of FH for Northern Europeans that cover 95% of cases. My mothers side of the family is Indian but I know for sure her cholesterol is fine. My fathers was fine from what I could remember but I'm not sure (he's the European side).

  10. #20
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    If you think you need statins then you don't understand cholesterol and how it actually works in the body. And if you really want the testing, get another doctor (if yours won't do it.) Statins do NO GOOD for people of your demographic.

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