It depends on your body and any existing sensitivity. I'm neither lactose intolerant nor gluten sensitive, so when I have a cheat meal and eat both these things, I feel like crap immediately only because I overeat, and everything goes on as usual the next day. Others can get horrible inflammation, bloating, etc.
F 28/5'4/100 lbs
"I'm not a psychopath, I'm a high-functioning sociopath; do your research."