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Thread: Warning against Ketogenic diets during pregnancy

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  1. #1
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    Warning against Ketogenic diets during pregnancy

    There are studies done that found that if women are on a ketogenic diet during pregnancy the gene expression on the baby is changed as the baby thinks it is going into a starvation environment and changes their metabolism permanently to store fat. Ketogenic diets over long periods of time can also cause your t3/t4 ratio out of whack which screws up your thyroid.

    Final Note: Primal/Paleo does not have to be ketogenic
    Primal since March 2011

    Female/29 years old/5' 1"/130ish lbs

  2. #2
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    I suppose if Grok's mate was PG and only ate meat, it would account for the *thrifty gene* we keep hearing about?

  3. #3
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    Quote Originally Posted by Nady View Post
    I suppose if Grok's mate was PG and only ate meat, it would account for the *thrifty gene* we keep hearing about?
    Seems very plausible. I'm glad I found that out before hand because I'll certainly make a point to eat a lot more carbs then I do now when I'm pregnant (since now I only eat >100g a couple days a week, with some days <50)
    Primal since March 2011

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  4. #4
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    Quote Originally Posted by activia View Post
    There are studies done that found that if women are on a ketogenic diet during pregnancy the gene expression on the baby is changed as the baby thinks it is going into a starvation environment and changes their metabolism permanently to store fat. Ketogenic diets over long periods of time can also cause your t3/t4 ratio out of whack which screws up your thyroid.

    Final Note: Primal/Paleo does not have to be ketogenic
    Hi, do you have any links for the studies? When I googled I didn't have much luck. I do keep my carbs above100 anyway (due to an already-screwed-up thyroid) and have increased it to be over 150 now. So it's not a concern for me, but I'm pregnant and am curious about it. Thanks!

  5. #5
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    Quote Originally Posted by Jen AlcesAlces View Post
    Hi, do you have any links for the studies? When I googled I didn't have much luck. I do keep my carbs above100 anyway (due to an already-screwed-up thyroid) and have increased it to be over 150 now. So it's not a concern for me, but I'm pregnant and am curious about it. Thanks!
    Sorry Chris said it during a podcast. I'd have to listen to it again to catch the exact details enabling me to find the study. It's possible it wasnt done on humans? He's just starting to get transcripts and links to the studies in his podcasts.. and this is an older one that hasnt yet been transcribed, hopefully soon. After I'm done listening to this one I'll get back to that one and see if I can find out more details for ya. Or you can listen yourself and add to this thread

    Low cholesterol is associated with higher risk of death in women
    Primal since March 2011

    Female/29 years old/5' 1"/130ish lbs

  6. #6
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    Yeah, where are you getting that info from?

  7. #7
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    maybe this is it?
    http://ep.physoc.org/content/55/2/83.full.pdf

    I'm still working on it.. I am running it now, its about mid way so it will probably be about 20 min
    Primal since March 2011

    Female/29 years old/5' 1"/130ish lbs

  8. #8
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    Hi,
    I just googled, and found this page Ketogenic Diet For Pregnancy | LIVESTRONG.COM
    It only mentions diabetic ketoacidosis, and says "No studies have specifically tested the effects of ketosis during pregnancy" This article was dated July 14, 2011

  9. #9
    I would find this much more compelling if the linked studies had actually examined the effects of low blood sugar on the development of the fetus. The speculation on a link between ketones and epigenetic programming is an interesting thought, but I don't see any evidence that it's actually true. Which is important when it comes to making scientific claims.

  10. #10
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    Quote Originally Posted by gcbcb View Post
    I would find this much more compelling if the linked studies had actually examined the effects of low blood sugar on the development of the fetus. The speculation on a link between ketones and epigenetic programming is an interesting thought, but I don't see any evidence that it's actually true. Which is important when it comes to making scientific claims.
    Marcus Pembrey's research has shown that epigenetic modifications are inherited and it can take a few generations for them to disappear if the stimulus that caused them disappears from the environment. He's found that the grandchildren of Brits who lived through rationing in World War 2 as young children are more likely to be obese than those whose grandparents didn't go through that experience.

    Research in epigenetics is very much in its infancy. We can only speculate on what the long-term consequences of radical changes in our diet will be.

    An absence of scientific evidence to prove that an extreme diet is not safe is not good enough for me. I want strong scientific evidence that it is safe for my ancestral group and demographic before I'll even consider any extreme diet.
    Last edited by paleo-bunny; 03-07-2012 at 05:46 AM. Reason: grammar
    F 5 ft 3. HW: 196 lbs. Primal SW (May 2011): 182 lbs (42% BF)... W June '12: 160 lbs (29% BF) (UK size 12, US size 8). GW: ~24% BF - have ditched the scales til I fit into a pair of UK size 10 bootcut jeans. Currently aligning towards 'The Perfect Health Diet' having swapped some fat for potatoes.

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