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Thread: How/when is dietary fat stored as fat? page

  1. #1
    nickh's Avatar
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    Could someone please explain how dietary fat (IE: fat that you eat) is stored as fat in your body?


    I understand that carbs are stored as fat easily, because insulin causes excess glucose in your blood to be stored as fat in various cells.


    However, I haven't been able to find any explanation of what process(es) cause dietary fat to be stored as fat.


  2. #2
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    http://en.wikipedia.org/wiki/Fatty_acid_metabolism


    Triglycerides break down into three glycerols (which are converted into glucose via gluconeogenesis) and one fatty acid. The glycerol components can of course be stored as adipose tissue when an excess of fat calories are consumed like any other sugar, but fatty acids break down into ketones, which are either used or excreted.


    So triacylglcerol -> three glycerols + one fatty acid -> glucose -> stored body fat


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    From Carnivore Health:

    "An enzyme called ASP (Acylation Stimulating Protein). This little jewel has the ability to directly store fat in the fat cells completely bypassing the glucose and insulin pathways.


    On a zero carb diet, excess fatty acids not immediately needed for energy will be directly stored in the fat cells through ASP. This stored fat will then be called upon as the body needs energy and is mobilized out of the fat cells through Hormone Sensitive Lipase (HSL) which will only allow body fat metabolism if insulin, a hormone, is low, hence ‘hormone sensitive’.


    As long as the total fat stored is equal to the total fat consumed, body fat will not accumulate. However, if, on average, less energy is needed than was stored, not all fat stored by ASP from the ZC meals will be remobilized by HSL and body fat will rise."


    http://www.carnivorehealth.com/main/2009/8/22/a-high-fat-diet-like-really-high-fat.html


    http://conditioningresearch.blogspot.com/2008/04/its-not-just-carbs.html


    Hope this helps!


  4. #4
    MikeGP's Avatar
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    Iceskater, you seem to know your stuff. Good. So people, pay attention, you CANT eat all the fat you want and not gain weight as long as youre "not eating carbs".


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    I'm not a biochemist or whatever, but I agree.

    Relying on fat for calories has benefits over being predominately reliant on carbs. A primary one is that eating more fat leads to great satiety/fullness over time, and hence, you aren't eating as many calories.


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    My take in it is that hopefully, the body will determine how much to eat. All we have to do is make the right foods available.


    If our metabolic hormones are in good working order and we learn to listen to our body, then the body will eat what it needs to achieve optimal health. A body in optimal health will express itself with an optimal weight and optimal fitness, optimal mind, optimal etc.

    “It is a truism that almost any sect, cult, or religion will legislate its creeds into law if it acquires the political power to do so, and will follow it by suppressing opposition, subverting all education to seize early the minds of the young, and by killing, locking up, or driving underground all heretics.”
    —Robert A. Heinlein

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    Tarlach's Avatar
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    [quote]

    So people, pay attention, you CANT eat all the fat you want and not gain weight as long as youre "not eating carbs".
    </blockquote>


    Of course you can and many of us DO.


    Iceskater showed how fat can be stored, not that this results in fat storage. Its not &#39;fat in&#39; - &#39;fat burned&#39;.


    It is quite possible to eat an immense amount of fat and not store any body fat.


    If you have no carbs you run out of glycerol to transport and store fatty acids in adipose tissue (as the glycogen is used elsewhere). It is then impossible to store excess body fat.


    Never mind futile cycling or other metabolic changes from eating ZC.


    It is a hell of a lot more complicated than &#39;burn more fat than you eat&#39;.

    The "Seven Deadly Sins"

    • Grains (wheat/rice/oats etc) . . . . . • Dairy (milk/yogurt/butter/cheese etc) . . . . .• Nightshades (peppers/tomato/eggplant etc)
    • Tubers (potato/arrowroot etc) . . . • Modernly palatable (cashews/olives etc) . . . • Refined foods (salt/sugars etc )
    • Legumes (soy/beans/peas etc)

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    Carbohydrates promote fat storage by providing the materials (glycerol), as well as the hormonal environment (insulin) for fat storage.

    I referred to the bible, GCBC:

    "..burning glucose for fuel is an essential component in the regulation of fat metabolism-storing fat in the fat tissue"


    The more glucose consumed.."the more glycerol phosphate produced, the more fatty acids assembled into triglycerides"-ie glycerol binds 3 fatty acids into a triglyeride=fat storage.


    Also, carbohydrates elevate insulin (allowing fatty acids into the fat cells), which suppresses all other hormones that can promote fat breakdown (but can only do so "when insulin levels are low").


    So blood sugar regulates the "flow of fatty acids in and out of the fat cells."


    However, Carnivore Health points out that glucose can also come from the liver, and other factors:


    "Glucose can go sky high in an instant without any glucose or protein consumption whatsoever, even in the fasting state with whole body glucose deficit running for many hours at a time. Transient changes in insulin resistance, including hormone mediated effects on the various glucose transporter molecules, can raise blood sugar and so can increases in glycolysis in the liver. It is erroneous to infer what is happening to consumed macronutrients based on blood glucose measurements."


    I think calories DO affect fat storage, even while VLC. I think this may be from pre-existing glycogen stores, or glucogenesis from protein? (I havent done research on this point, please feel free to correct me


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    Tarlach's Avatar
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    It is possible to store fat on ZC. It is highly unlikely that you will store excess body fat on ZC. You need to have seriously damaged part of the regulating system.


    If you aren&#39;t restricting calories, the body reaches homeostasis and ignores excess calories. You do not get fat on ZC, even if eating excessive calories.


    http://magicbus.myfreeforum.org/about1484.html

    The "Seven Deadly Sins"

    • Grains (wheat/rice/oats etc) . . . . . • Dairy (milk/yogurt/butter/cheese etc) . . . . .• Nightshades (peppers/tomato/eggplant etc)
    • Tubers (potato/arrowroot etc) . . . • Modernly palatable (cashews/olives etc) . . . • Refined foods (salt/sugars etc )
    • Legumes (soy/beans/peas etc)

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    http://www.dhslides.org/mgr/mgr060509f/f.htm


    the whole thing is very interesting and only 50mins long, but click on "thumbs" and click the one which is at time interval 42:35 for more explanation about how fat is stored


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