I never said anything about disastrous metabolic damage, but rather malabsorption, which would actually be somewhat protective, as not as much hits the bloodstream. It could well be an adaption to keep us from getting too much. But if you can't absorb it then it goes on into the gut where it is fermented by bacteria. This is a different set of problems. There's the classic gut reaction, diarrhea/constipation/gas/pain and then it's also been linked to depression, anxiety, aches, fatigue and so on. And if you'll look at what I actually wrote you would see that the levels that a person can absorb vary, some being able to handle more than others. And women tend to be more susceptible than men, so you personally have that advantage. As for the intelligence of mother nature, I don't disagree. But up until recently most populations didn't have access to the levels of fructose now available to most. Not just in the form of HFCS and other processed foods, but fruit wasn't a constant. Even when it was available it was doubtful that there was enough for everyone to eat 4-5 pieces of fruit daily for months at a time. Gorging on fruit for a day or two then leveling out your consumption (which is a more likely scenario than gorging every day all year long) isn't likely to result in serious issues. Following are some links that go further into detail about what I' saying. And yes, in a research setting people were ingesting fructose in a liquid form, as it's much more efficient and one can control how much fructose a person actually ingests. But for those with FM eating an apple will have the same effect as downing a HFCS sweetened drink.
https://sites.google.com/site/fructmal/research
http://www.wjgnet.com/1007-9327/13/5687.pdf



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