Leptin Reset Experiment starts today - Jack Kruse style page 1366

[MamaGrok]

I have NO IDEA what she tested to give me the diagnosis of leaky gut, and I am still looking for a way to figure out if it is healing, healed, etc. I think if I understand my reading of this thread correctly (and Dr. Kruse's site) that the VAP can be used. I think if you have mostly large "A type" LDLs versus "B type" LDLs then you don't have leaky gut and if it is the other way around then you DO have a leaky gut. BUT, my previous doctor never did a VAP or NMR on me, so I have no clue how she arrived at the diagnosis.

Please someone correct me if that is not how you can diagnose leaky gut...

Also, how come you want to avoid EVOO? I prefer the CO, pastured butter, ghee too. Just curious.

EVOO=omega 6. Avoid till omega 6:3 ratio is closer to 2:1 or 1:1.

HDL 89
Trig. 75
hsCRP 2

Can I assume LS ness?

My HDL is >80. Trig <100. Ratios show pattern A (will have VAP soon).

Yet my biggest, most persistent problem is abdominal distension. IDK what to think!

[Snauzoo]

EVOO=omega 6. Avoid till omega 6:3 ratio is closer to 2:1 or 1:1.



My HDL is >80. Trig <100. Ratios show pattern A (will have VAP soon).

Yet my biggest, most persistent problem is abdominal distension. IDK what to think!

That is really baffling I agree. I would be tempted to get an ultrasound.

[kkcarlton]

I've been having 4 eggs and 2 oz of some kind of meat. That puts me around 46-48oz of protein dependent on the meat.

According to myfitnesspal.com, 4 large eggs have 24 grams of protein. Then I chose 2 ounces of 80/20 ground beef, which has 10 grams of protein for a total of 34 grams. How are you figuring the grams of protein in what you are eating. It seems low.

[kathylu]

Isabell, I'm at a similar point as you are. I wondered if I have leaky gut, so I did a VAP, HS CRP, and RT3/FT3 and learned how to attempt to hack the results. I saw that my HDL was at 68, and...

Dr. K says "...down around 40 is a marker for leaky gut". And more, "A high HDL is a sign of good liver function. Remember that HDL particles actually bind inflammatory endotoxin particles to increase our immunity from oxidation from many sources. This is why a high HDL level confers general health and well being across the board." Moreover, VLDL and chylomicrons also protect us from inflammatory damage as well. This biologic process is at the seat of why we see higher cholesterol levels in the face of cellular stress or infection."

Hmm. I still wondered, so I went off all dairy, wheat, nightshades, grains, eggs, all in a test to see how I did. I am also coming at this with an autoimmune angle and these are all irritants. I had started the Leptin Reset two weeks earlier and really chowed down on the coconut oil and bone broths, both heal leaky gut. I figured I'd give it the best shot I can. Experimentation and observation.

Other test to compare are HS CRP and Thyroid screening.

Kruse again, "The increased secretion of TSH from the pituitary has a major effect on out liver too. It is pro-inflammatory because it causes the liver to make HS-CRP (Highly Sensitive . HS-CRP is what we used to measure baseline inflammation in patients. It is called an acute phase reactant protein. High CRP levels are known to walk hand and hand with the development of atherosclerosis. The increased CRP produces multitudes or pro inflammatory chemicals body wide, because they activate immune cells like Mast cells. Mast cells and other immune cells, are the factories of pro inflammatory chemicals and they stimulate more inflammation in the plaques of atheromas in blood vessels to rupture and cause disease.

More Kruse: "If you read about nightshades, they cause issues similar to a leaky gut. So if you re read my VAP= Leaky gut post you will see that I use the VAP as a proxy to see if the gut is leaky. Most people doing a reset all have really bad HDL levels. This means the liver is not as good a filter as it could be. IE the gut is leaky to more inflammation than it need be. This is also why the HS CRP is higher. It tells us that the plasma is more oxidative to our systems. And this fosters leptin resistance. Therefore, during the reset we want to do everything possible to eliminate inflammation and that is why you should avoid the nightshades. And if you happen to get a lipid panel on your reset……and as a female your HDL is above 60, or as a male above 70, then I say you can eat nightshades on the reset. In my six years of doing this I have not seen a LR person who fit that bill as yet."


K: "High TSH levels are not good signs. This is why hypothyroidism is correlated with heart disease and many autoimmune conditions. Hashimoto’s thyroiditis is an epidemic in America and in my view is a sign of a constant assault of the intestinal brush border of our gut that eventually overwhelms it and then floods the portal circulation with inflammation. This results in a liver response that, over time, goes from favorable (particle A LDL size with high HDL) to a very unfavorable particle B size dominated by sdLDL and low HDL and a high HS CRP. This then sets the stage for disease propagation in many sites of the body."


My autoimmune issues (possible Lyme infection) has it's own set of pathways which I'm struggling to learn. But I feel like my Leaky Gut is being addressed if need be. It's good basic human nutrition. And those broths are so good!!!!

Martin

I guess I'm the exception then. My HDL has ranged from 87 to 91 on the last 4 tests, but I have a massive, unrelenting candida infection! HS CRP is 1.6 so inflammation is present. I've been fighting it for over a year, but it keeps coming back. Of course, I eat lots of fermented veggies, bone broth and coconut oil. I finally had to resort to taking diflucan 4 days per week. That keeps the symptoms low, but is not a cure. Diflucan is fungistatic, not fungicidal. I live my life as if I had leaky gut, even though the tests do not indicate that I do. However, after reading Dr. K's info, I did put small amounts of nightshades back in my diet for variety. I was missing those tomatoes and peppers....

[Shijin13]

According to myfitnesspal.com, 4 large eggs have 24 grams of protein. Then I chose 2 ounces of 80/20 ground beef, which has 10 grams of protein for a total of 34 grams. How are you figuring the grams of protein in what you are eating. It seems low.

FYI you're responding to a spambot.

[kkcarlton]

FYI you're responding to a spambot.

DUH! So sorry...apparently I am not fully awake yet.

[Shijin13]

DUH! So sorry...apparently I am not fully awake yet.

Sometimes it takes a while to recogonize their patterns. When they start quoting you from earlier posts or they keep quoting the same posts it becomes obvious.

[DigitalSurgeon]

I guess I'm the exception then. My HDL has ranged from 87 to 91 on the last 4 tests, but I have a massive, unrelenting candida infection! HS CRP is 1.6 so inflammation is present. I've been fighting it for over a year, but it keeps coming back. Of course, I eat lots of fermented veggies, bone broth and coconut oil. I finally had to resort to taking diflucan 4 days per week. That keeps the symptoms low, but is not a cure. Diflucan is fungistatic, not fungicidal. I live my life as if I had leaky gut, even though the tests do not indicate that I do. However, after reading Dr. K's info, I did put small amounts of nightshades back in my diet for variety. I was missing those tomatoes and peppers....

this makes a great point for the thread......just because the HDL was good does not mean all is well......this is why testing paints a fuller picture. the back round CRP told you to keep digging. And Candida is a a very very common problem in this country because of the carb loving people in america is met with the SAD template. Now I would have told you diflucan is a great idea but since you have had trouble getting rid of it you might need an ID consult to wipe it out with a multi drug platform. Then with a sterilized gut you rebuild your flora. I also would have made coconut oil a huge part of your bone broths because it is anti- fungal for the most part. I also would have suggest a complete nightshade free situation for 6-12 months while you rebuild your flora. I might have had you in with a provider who understands constant surveillance with a GI fx testing platform. Candida takes a while to get rid of but you will never sniff optimal if you have it!!!! Candida also subverts your hormonal response more so than many other opportunist infection because it is commonly associated with women who are LR. The LR fosters IL-6 and this protects the fungi environment in the gut. This is why you need to go nuclear to get rid of it.

There is also the same faction of people in paleo that are trying to push up carb levels to just ridiculous levels and say its just fine. When people get there they are still struggling and they want answer that the carb guru's just cant answer. One can tolerate a very high carb template provided the gut is fixed, your D levels are great and you are very LS and you exercise properly........then I am completely on board. One problem........that makes up less than 5% of the population that comes into my office. CONTEXT!!!! IS KEY

[PrimalPam]

this makes a great point for the thread......just because the HDL was good does not mean all is well......this is why testing paints a fuller picture. the back round CRP told you to keep digging. And Candida is a a very very common problem in this country because of the carb loving people in america is met with the SAD template. There is also the same faction of people in paleo that are trying to push up carb levels to just ridiculous levels and say its just fine. When people get there they are still struggling and they want answer that the carb guru's just cant answer. One can tolerate a very high carb template provided the gut is fixed, your D levels are great and you are very LS and you exercise properly........then I am completely on board. One problem........that makes up less than 5% of the population that comes into my office. CONTEXT!!!! IS KEY

This would be a great blog topic for you, Dr. Kruse. Would love to see your expanded thoughts on this topic. I believe candida is a bigger problem than we realize, as just doing a search for "Low Carb Flu" will yield thousands of results. I had a terrible sort throad and lost my voice for 3 days when I truly went LC, which I'm now certain was a candida die-off infection.

And your views that tolerating carbs once a person is LS and the gut is fixed, etc., is also fascinating.

[colleencoble]

Very sad to receive an email just now that Dr. John Lowe died on the 9th of a head injury. His protocol for T3 changed my life. His wife said that he just completed a forward to a book titled 'Recovering with T3' by Paul Robinson and a forward for the book, The Hormone Zone, by Dr. John Robinson. He also conducted an interview for Dr. Mark Swanson that will soon be published. And finally, he was also working to complete his own book, 'Safely Getting Well With Thyroid Hormone' and was preparing to have it in print within a few weeks. I hope it makes it. I'd like to read it.