nutmeggs, I'm interested to know what other in-the-thyroid-know folks have to say about your skyrocketing antibodies. IDK squat about thyroid minutiae, but I have a feeling I'll need to in the near future.
Owl, THANK YOU for posting that the post-leptin RX explains how the RS works. I'm way behind in reading the blogs (have to go very slowly when I'm inbrain-fog and/or low energy states, which seems to be most of the time lately ), but I just glanced through those portions. So glad to read the explanation finally!
So please correct me if I'm wrong, but I want to summarize what I read to be sure I understand it.
In biological history, circadian (once a day) & ultradian (several times a day, like sleep cycles & elimination & eating) rhythms are the most primitive way to regulate certain functions like appetite & energy use or storage (fat maintenance, gain, or loss). More biologically simple creatures use amount of food consumed in relation to the sun's rising and setting to determine whether enough food seems to be available, and whether energy should be stored or burned, and whether appetite should be up- or down-regulated.
We're advanced! (woohoo!) People have a (relatively speaking) new hormone called leptin that is made by the fat cells and tells the leptin receptors at the brain & muscles & liver whether or not there is enough fat for a rainy day, or whether we need to stop moving & eat more to build up the backup supply. It's an upgrade. But like all upgrades, it's a bit less stable than the most basic model, and it can go awry when feeding becomes grossly departed from what is biologically natural for us.
At that point (and I've forgotten why this happens; will review later - does the onslaught of massive amounts of carbs make insulin tell leptin to tell the brain "MAKE MORE FAT! MAKE MORE FAT!"?), our leptin receptors are being bombarded by leptin and just get tired of it and say SHUT UP ALREADY! and no longer pay any attention to what leptin has to say. So whether the leptin is high or low, it doesn't matter, b/c the receptors are sticking their fingers in their ears and saying La la la la la I can't heeeeeaaaarrrrr you!!!
BUT - says Dr. Kruse - there is a backup plan. When a newfangled signal like leptin no longer makes sense to the brain, it reverts to using older biological mechanisms for the functions needed. So the body reverts to using circadian & ultradian rhythms to regulate fat storage. That means that *when* you eat how much tells your body how much fat to store. So eating a big ol' breakfast signals your body that plenty of food is available and fat stores do not need to be increased. (Since I forget why there's so much leptin in the first place, I don't quite follow why this tells the brain to start making less of it ... maybe the low carb diet has already down-regulated the amount of leptin produced, but it didn't matter b/c the receptors were still ignoring it. But what is it that now makes them unplug their ears? Maybe just enough time of the combination of low-carb + the signal from the food timing that tells the brain "Food is not in short supply now"?)
Now you can lose fat. And gain energy. Hurrah!
Corrections welcome! I'm trying to pull all these bits and pieces to understand what's going on. This makes me realize that my really irregular sleep patterns are REALLY holding me back. I'm getting enough sleep each day by just staying in bed when sleep is interrupted (whether by a child, staying up late, mid-night waking, or waking too dang early not my fault at all), but my breakfast is all. over. the.map, any time from 7:30 to 11am.