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Thread: Gluconeogenesis page

  1. #1
    GotPrimal's Avatar
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    This has been a hot topic lately, and Im a bit honored to post here first.


    I think we all could benefit from some sound science exploring this topic.


    The basics, the intermediates, the advanced.


    My first primer question, if someone is in a state of ketosis (around or under 50 carbs a day), when the body uses gluconeogensis to create carbs from protein, does this cause correlated rise in insulin?


  2. #2
    BigBeck89's Avatar
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    I'd assume yes. because without the insulin to shuttle the newly made glycogen to your muscles then


    1: it would never get there


    2: you'd die.


    but I'm just assuming


  3. #3
    GotPrimal's Avatar
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    Not assuming specifically muscles per se, but for the organs that use/"need" carbs on a regular basis.


    Kidneys, Brain..


    Does the body need a spike in insulin for those organis to properly assimilate and use the glycogen created from protein?


    And if the answer is no, is the negative light cast upon gluconeogenesis warranted?


  4. #4
    BigBeck89's Avatar
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    same thing. its never going to leave your bloodstream to go to wherever without insulin


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  6. #6
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    nice video but...


    GNG happens in response to your liver having been depleted of glycogen. As in fasting.


    Insulin is also (one of)the feed back response that spares amino acids. As in stops GNG.


  7. #7
    eva's Avatar
    eva
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    http://books.google.fi/books?id=pjZvmnZpKXsC&pg=PA30&lpg=PA30&dq=gluconeo genesis+and+insulin+in+ketosis&source=bl&ots=nCZyZ rL6tz&sig=ctN9p_CAo_OKekPHmUdxSaucKEg&hl=fi&ei=pGA GS66hHovM-Qas56DGDQ&sa=X&oi=book_result&ct=result&resnum=2&v ed=0CA8Q6AEwATgK#v=onepage&q=gluconeogenesis%20and %20insulin%20in%20ketosis&f=false


    an extremely good read to explain insulin-glucagon metabolism... if you have the patiency to read it ofcourse...

    challenge yourself
    i blog here http://theprimalwoman.blogspot.com/

  8. #8
    chima_p's Avatar
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    @ eva


    Thanks. I will have to find some time over the weekend to read through that.


    Questions I have come across while reading about GNG:


    What level of isulin is considered a "spike"?


    What rate does GNG produce glucose?


    Are we not putting the cart berfore the horse when we talk insulin/blood sugar?


    Are we not turning Insulin into the new cholesterol?


  9. #9
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    Chima, I don't recall if these links specifically answer your questions, but they may help:


    http://www.proteinpower.com/drmike/ketones-and-ketosis/metabolism-and-ketosis/


    http://www.proteinpower.com/drmike/uncategorized/why-do-we-need-glucose/


    More tangentially related, but still interesting and potentially useful:


    http://www.proteinpower.com/drmike/metabolism/metabolic-efficiency/


    http://www.proteinpower.com/drmike/m...d-weight-loss/


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