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Thread: Thanks for the advice on beta-carotene in multi-vites :-) page

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    kuno1chi's Avatar
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    Primal Fuel


    klcarbaugh ,


    I'm having trouble finding the thread in which you gave me this advice, but I did check the mult-vite I had been taking, and it had a lot of beta-carotene in it.


    Stopped taking it for a few days...my OA-type hip pain is now gone. Who woulda thunk it???


    The bottle was lmost empty; I threw it out, and am shopping for a new one :-D


    Thanks for saving me from waddling around. That was deeply disturbing...


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    Thanks, Maba!!!

    Thanks to you also for sharing this information with me. I feel so very much better now.


    Amazing number of little land-mines out there, huh?


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    I was beginning to question myself about not taking the pre-natals. Your testimony convinces me that I'm doing the right thing after all.


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    maba,


    We're all here to help each other, right?


    If I can find a good multi without the synthetic beta-carotene, I'll be sure and post it here for you. In the meantime, I'm eating a lot more of those good dark-green leafies :-D


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    Your welcome kuni1chi!


    Actually I don't think that hardly any vitamins are synthetic. The thing about beta carotene is it is just 1 carotenoid instead of the multiple ones you find together naturally in a carrot or something. Beta is the easiest to extract and therefore the most profitable.


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    maba's Avatar
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    Katie, I stopped my pre-natals about 2 months ago and recently started taking 800mg of Folic Acid. And the husband sends me an article this morning that just came out in JAMA. I'm copying only the gist of it here. I'm yet to read the entire paper, but I'm thoroughly confused! I'm trying to get pregnant and want to make sure I get all the vitamins I need w/o pre-natals.


    Cancer Incidence and Mortality After Treatment With Folic Acid and Vitamin B12


    Context

    Recently, concern has been raised about the safety of folic acid, particularly in relation to cancer risk.


    Objective

    To evaluate effects of treatment with B vitamins on cancer outcomes and all-cause mortality in 2 randomized controlled trials.


    Design, Setting, and Participants

    Combined analysis and extended follow-up of participants from 2 randomized, double-blind, placebo-controlled clinical trials (Norwegian

    Vitamin Trial and Western Norway B Vitamin Intervention Trial). A total of

    6837 patients with ischemic heart disease were treated with B vitamins or placebo between

    1998 and 2005, and were followed up through December 31, 2007.


    Interventions

    Oral treatment with folic acid (0.8 mg/d) plus vitamin B12 (0.4 mg/d)

    and vitamin B6 (40 mg/d) (n=1708); folic acid (0.8 mg/d) plus vitamin B12 (0.4 mg/d)

    (n=1703); vitamin B6 alone (40 mg/d) (n=1705); or placebo (n=1721).


    Main Outcome Measures

    Cancer incidence, cancer mortality, and all-cause

    mortality.


    Results

    During study treatment, median serum folate concentration increased more than 6-fold among participants given folic acid. After a median 39 months of treatment and an additional 38 months of posttrial observational follow-up, 341 participants

    (10.0%) who received folic acid plus vitamin B12 vs 288 participants (8.4%) who did not receive such treatment were diagnosed with cancer (hazard ratio [HR], 1.21; 95% confidence interval [CI], 1.03-1.41; P=.02). A total of 136 (4.0%) who received

    folic acid plus vitamin B12 vs 100 (2.9%) who did not receive such treatment died from cancer (HR, 1.38; 95% CI, 1.07-1.79; P=.01). A total of 548 patients (16.1%) who received folic acid plus vitamin B12 vs 473 (13.8%) who did not receive such treatment

    died from any cause (HR, 1.18; 95% CI, 1.04-1.33; P=.01). Results were mainly driven by increased lung cancer incidence in participants who received folic acid plus vitamin B12. Vitamin B6 treatment was not associated with any significant effects.


    Conclusion

    Treatment with folic acid plus vitamin B12 was associated with increased cancer outcomes and all-cause mortality in patients with ischemic heart disease in Norway, where there is no folic acid fortification of foods.


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