Actually, insulin is still pretty much a proximal cause and not the root of the issue: high (fasting) insulin is caused by hepatic insulin resistance, which is caused by the ingestion of toxins like excess fructose and PUFAs. Additionally, PUFAs and hyper-palatable modern foods interfere with satiety and appetite signalling. I'm sure repletion or deficiency of micronutrients also plays a role. It's really too complex to adequately sum up in a nice, short aphorism, but one of the better summaries I've seen is Chris Kresser's: Avoid toxins. Nourish the body. Eat real food.



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