Isn't against the grain the same as across it?
I think with any tougher cut of meat, you always want to cut it in a way that ends up with short fibers (I would phrase that as across the grain). If it's a tough meat and you cut in the direction of the grain, you're going to keep the long tough fibers, which could be like eating string.
Zone diet on and off for several years....worked, but too much focus on exact meal composition
Primal since July 2010...skinniest I've ever been and the least stressed about food