Yeah I just got introduced to them today by The Healthy Skeptic and it all looks great. Tons of great information with.... valid citations. Wahoo! *raccoon dance*
My one beef is that it has yet to be demonstrated that methionine has anywhere near the effect on mTOR in humans as it does in mice. And since humans were primarily meat eaters for a long time it would make sense to have some sort of a smart feedback mechanism AND also to be able to utilize protein to our benefit far exceeding any downsides to increased mTOR from say, 20% energy rather than 10%. I bet that insulin levels and cholesterol levels tie into it as well and so I wouldn't just say 200 calories from protein and that's that. A high fat, low carb low protein diet is either seriously low in nutrients or seriously high in omega 6 so I'm having a hard time calling that "optimal". If all else fails I would just use gelatin which doesn't have methionine and the most nutrient-dense protein sources.
Stabbing conventional wisdom in its face.
Anyone who wants to talk nutrition should PM me!